MENG LING MOI

Profile Information

Affiliation: Professor, Department of Developmental Medical Sciences, School of International Health, Graduate School of Medicine, The University of Tokyo
: (Concurrent)Senior Researcher, Pandemic Preparedness, Infection and Advanced Research Center

Degree: PhD Medical Science(Tsukuba University)

Researcher number: 40597499
J-GLOBAL ID: 201301072112487869
researchmap Member ID: B000231069

External link: https://www.development.m.u-tokyo.ac.jp/en/

Research Interests

Research Areas

Research History

Oct, 2023 - Present

Adjunct Instructor, University of Tsukuba
Oct, 2022 - Present

Senior Researcher, The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center
Oct, 2021 - Present

Professor, Department of Developmental Medical Sciences, School of International Health, Graduate School of Medicine, The University of Tokyo
Jan, 2015 - Present

Visiting Fellow, National Institute of Infectious Diseases
Feb, 2020 - Sep, 2021

Professor, Institute of Tropical Medicine Research Field of Microbiology, Nagasaki University
Jan, 2015 - Jan, 2020

Associate Professor, Institute of Tropical Medicine Research Field of Microbiology, Nagasaki University
Apr, 2010 - Dec, 2014

Researcher, Virology 1, National Institute of Infectious Diseases

Education

Apr, 2006 - Mar, 2010

Graduate School of Comprehensive Human Sciences, University of Tsukuba
Apr, 2004 - Mar, 2006

Master's Program in Medical Sciences, University of Tsukuba
Apr, 2003 - Mar, 2004

School of Humanities and Culture, College of Japanese Language and Culture, University of Tsukuba
Mar, 1999 - Feb, 2002

University Putra Malaysia

Committee Memberships

Nov, 2024 - Present

Board Council, Japanese Society of Tropical Medicine
Feb, 2022 - Present

Advisory Board, Advisor, Japan Agency for Medical Research and Development
Dec, 2020 - Present

Advisory board Member, Program for the Development of Next-generation Leading Scientists with Global Insight, Kyoto University.

Awards

Dec, 2020

AMED Director's Award, Japan Agency for Medical Research and Development

MENG LING MOI
Nov, 2019

Female Researcher Prize, Japanese Society of Tropical Medicine, Japanese Society of Tropical Medicine

MENG LING MOI
Oct, 2018

Sugiura Award, Japanese Society of Virology

MENG LING MOI
Feb, 2018

Best Paper Award, Doumonkai, Institute of Tropical Medicine, Nagasaki University

MENG LING MOI
Feb, 2018

Mirai-ni-Habataku Female Researcher Award, Nagasaki University

MENG LING MOI
Dec, 2016

Incentive Prize for Medicine, MSD Life Science Foundation

MENG LING MOI
Apr, 2016

Young Scientist Prize, Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, Ministry of Education, Culture, Sports, Science and Technology

MENG LING MOI
Nov, 2013

Malaysia Japan Academic Conference, Best Poster Award

MENG LING MOI
Mar, 2010

Tsukuba University, Graduate School of Human Sciences, Dean’s Award for Research Excellence

MENG LING MOI

Papers

101

Genomic sequencing and neutralizing serological profiles during acute dengue infection: A 2017 cohort study in Nepal.

Sabita Prajapati, Annie Elong Ngono, Melanie Mc Cauley, Julia Timis, Srijan Shrestha, Anup Bastola, Shrawan Kumar Mandal, Sanjay Ray Yadav, Rajindra Napit, Meng Ling Moi …

bioRxiv : the preprint server for biology, Jun 5, 2024
A tetravalent dengue virus-like particle vaccine induces high levels of neutralizing antibodies and reduces dengue replication in non-human primates.

Daniel Thoresen, Kenta Matsuda, Akane Urakami, Mya Myat Ngwe Tun, Takushi Nomura, Meng Ling Moi, Yuri Watanabe, Momoko Ishikawa, Trang Thi Thu Hau, Hiroyuki Yamamoto …

Journal of virology, 98(5) e0023924, May 14, 2024 Peer-reviewed
Development and validation of cost-effective SYBR Green-based RT-qPCR and its evaluation in a sample pooling strategy for detecting SARS-CoV-2 infection in the Indonesian setting.

Ratika Rahmasari, Muhareva Raekiansyah, Siti Hana Aliyah, Priska Yodi, Fathan Baihaqy, Muhamad Irhamsyah, Kartika Citra Dewi Permata Sari, Herman Suryadi, Meng Ling Moi, Rani Sauriasari

Scientific reports, 14(1) 1817-1817, Jan 20, 2024 Peer-reviewed
Analysis of antiviral drug properties of thymidine kinase of herpes B virus using recombinant herpes simplex virus 1.

Phu Hoang Anh Nguyen, Shuetsu Fukushi, Souichi Yamada, Shizuko Harada, Tomoki Yoshikawa, Hitomi Kinoshita, Madoka Kawahara, Takuma Ogawa, Hideki Ebihara, Meng Ling Moi …

Microbiology spectrum, 12(1) e0309123, Jan 11, 2024 Peer-reviewed
Utility of an In-Vitro Micro-Neutralizing Test in Comparison to a Plaque Reduction Neutralization Test for Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Serology and Drug Screening.

Kazumi Haga, Zhenying Nancy Chen, Misao Himeno, Ryuichi Majima, Meng Ling Moi

Pathogens (Basel, Switzerland), 13(1), Dec 20, 2023 Peer-reviewedLast authorCorresponding author
Role of pre-existing immunity in driving the dengue virus serotype 2 genotype shift in the Philippines: A retrospective analysis of serological data.

Jean Claude Balingit, Mark Pierre S Dimamay, Ryosuke Suzuki, Mami Matsuda, Dalouny Xayavong, Mya Myat Ngwe Tun, Ronald R Matias, Filipinas F Natividad, Meng Ling Moi, Yuki Takamatsu …

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 139 59-68, Nov 27, 2023 Peer-reviewed
Comparative analysis of the susceptibility of Aedes aegypti and Japanese Aedes albopictus to all dengue virus serotypes.

Daisuke Kobayashi, Izumi Kai, Astri Nur Faizah, Meng Ling Moi, Shigeru Tajima, Tomohiko Takasaki, Toshinori Sasaki, Haruhiko Isawa

Tropical medicine and health, 51(1) 61-61, Nov 2, 2023 Peer-reviewed
Pre-existing cross-reactive neutralizing activity against SARS-CoV-2 and seasonal coronaviruses prior to the COVID-19 pandemic (2014-2019) with limited immunity against recent emerging SARS-CoV-2 variants, Vietnam

Thi Thanh Ngan Nguyen, Ee Mei Choo, Yukio Nakamura, Ryuji Suzuki, Takashi Shiina, Tadasu Shin-I, Mizuki Fukuta, Co Thach Nguyen, Thi Thu Thuy Nguyen, Le Khanh Hang Nguyen …

International Journal of Infectious Diseases, 139 109-117, Nov, 2023 Peer-reviewedLast authorCorresponding author
Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases.

Yukio Nakamura, Meng Ling Moi, Takashi Shiina, Tadasu Shin-I, Ryuji Suzuki

Viruses, 15(5), May 17, 2023 Peer-reviewed
Serological Evidence of Zika virus Circulation with Dengue and Chikungunya Infections in Sri Lanka from 2017.

Harshi Abeygoonawardena, Namal Wijesinghe, Varuna Navaratne, Aindralal Balasuriya, Thi Thanh Ngan Nguyen, Meng Ling Moi, Aruna Dharshan De Silva

Journal of global infectious diseases, 15(3) 113-120, 2023
Differential Infectivity of Human Neural Cell Lines by a Dengue Virus Serotype-3 Genotype-III with a Distinct Nonstructural Protein 2A (NS2A) Amino Acid Substitution Isolated from the Cerebrospinal Fluid of a Dengue Encephalitis Patient.

Minh Huong Phu Ly, Co Thach Nguyen, Thanh Vu Nguyen, Thanh Thi Ngan Nguyen, Takeshi Nabeshima, Ferdinard Adungo, Yuki Takamatsu, Nguyen Tien Huy, Thi Quynh Mai Le, Kouichi Morita …

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2023 2635383-2635383, 2023 Peer-reviewedLast authorCorresponding author
Novel Antiviral Efficacy of Hedyotis diffusa and Artemisia capillaris Extracts against Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Infection and Immunoregulatory Cytokine Signatures.

Zhan Qiu Mao, Noboru Minakawa, Meng Ling Moi

Plants (Basel, Switzerland), 11(19), Sep 30, 2022 Peer-reviewedLast authorCorresponding author
Acute-phase Serum Cytokine Levels and Correlation with Clinical Outcomes in Children and Adults with Primary and Secondary Dengue Virus Infection in Myanmar between 2017 and 2019.

Khine Mya Nwe, Mya Myat Ngwe Tun, Theingi Win Myat, Chris Fook Sheng Ng, Moh Moh Htun, Htin Lin, Nang Sarm Hom, Aung Min Soe, Annie Elong Ngono, Shinjiro Hamano …

Pathogens (Basel, Switzerland), 11(5), May 9, 2022 Peer-reviewedLast authorCorresponding author
Corrigendum to "The novel therapeutic target and inhibitory effects of PF-429242 against Zika virus infection" [Antivir. Res. vol 192 (2021) 1-13/105121].

Sandra Kendra Raini, Yuki Takamatsu, Shyam Prakash Dumre, Shuzo Urata, Shusaku Mizukami, Meng Ling Moi, Daisuke Hayasaka, Shingo Inoue, Kouichi Morita, Mya Myat Ngwe Tun

Antiviral research, 199 105245-105245, Mar, 2022
The 2017 Dengue virus 1 outbreak in northern Vietnam was caused by a locally circulating virus group.

Taichiro Takemura, Co Thach Nguyen, Ha Chau Pham, Thuy Trang Nguyen, Vu Mai Phuong Hoang, Le Khanh Hang Nguyen, Takeshi Nabeshima, Thi Thu Thuy Nguyen, Thi Quynh Mai Le, Meng Ling Moi …

Tropical medicine and health, 50(1) 3-3, Jan 4, 2022 Peer-reviewed
Direct Viral RNA Detection of SARS-CoV-2 and DENV in Inactivated Samples by Real-Time RT-qPCR: Implications for Diagnosis in Resource Limited Settings with Flavivirus Co-Circulation.

Zhan Qiu Mao, Mizuki Fukuta, Jean Claude Balingit, Thi Thanh Ngan Nguyen, Co Thach Nguyen, Shingo Inoue, Thi Thu Thuy Nguyen, Le Khanh Hang Nguyen, Noboru Minakawa, Kouichi Morita …

Pathogens (Basel, Switzerland), 10(12), Nov 29, 2021 Peer-reviewedLast authorCorresponding author
Genotype-Dependent Immunogenicity of Dengue Virus Type 2 Asian I and Asian/American Genotypes in Common Marmoset (Callithrix jacchus): Discrepancy in Neutralizing and Infection-Enhancing Antibody Levels between Genotypes.

Nor Azila Muhammad Azami, Meng Ling Moi, Yasushi Ami, Yuriko Suzaki, Satoshi Taniguchi, Shigeru Tajima, Masayuki Saijo, Tomohiko Takasaki, Ichiro Kurane, Chang-Kweng Lim

Microorganisms, 9(11), Oct 21, 2021 Peer-reviewed
Complexities in Case Definition of SARS-CoV-2 Reinfection: Clinical Evidence and Implications in COVID-19 Surveillance and Diagnosis.

Lisa Yamasaki, Meng Ling Moi

Pathogens (Basel, Switzerland), 10(10), Sep 29, 2021 Peer-reviewedLast authorCorresponding author
Discrepancies in Infectivity of Flavivirus and SARS-CoV-2 Clinical Samples: An Improved Assay for Infectious Virus Shedding and Viremia Assessment.

Mizuki Fukuta, Co Thach Nguyen, Thi Thu Thuy Nguyen, Thi Thanh Ngan Nguyen, Thi Bich Hau Vu, Taichiro Takemura, Le Khanh Hang Nguyen, Shingo Inoue, Kouichi Morita, Thi Quynh Mai Le …

International journal of environmental research and public health, 18(18), Sep 18, 2021 Peer-reviewedLast authorCorresponding author
Development and Evaluation of Quantitative Immunoglobulin G Enzyme-Linked Immunosorbent Assay for the Diagnosis of Coronavirus Disease 2019 Using Truncated Recombinant Nucleocapsid Protein as Assay Antigen.

Pierre Nsele Mutantu, Mya Myat Ngwe Tun, Takeshi Nabeshima, Fuxun Yu, Patrick Kakoni Mukadi, Takeshi Tanaka, Masato Tashiro, Ayumi Fujita, Nobuhiro Kanie, Ryosaku Oshiro …

International journal of environmental research and public health, 18(18), Sep 13, 2021 Peer-reviewed

Misc.

Chikungunya

MOI MENG LING

The Jounal of the Japan Medical Association, 152(4) 403-406, Jul, 2023 Lead authorCorresponding author
Dengue

Meng Ling Moi

Oct, 2022
Dengue virus disease protection and dechipering of adaptive immunity for vaccines and therapeuticcs development

MOI MENG LING

72(4) 306-310, Aug, 2021 Lead authorLast authorCorresponding author
Are there virus reproduction in patients without symptoms?

MOI MENG LING

The Japanese journal of nursing arts, 67(9) 962-964, Aug, 2021
Mechanisms of dengue virus infection

Mizuki Fukuta, Meng Ling Moi

Aug, 2021 Last authorCorresponding author
Zika Virus Infection

MOI MENG LING

79(2) 205-210, Feb, 2021 Lead authorCorresponding author
特別企画◎新型コロナウイルス感染症（COVID-19）「新型コロナウイルス感染症に対する検査の考え方

Moi Meng Ling, 森田公一

Jul, 2020 Lead authorCorresponding author
Towards the control of tropical and emerging infectious disease

Kouichi Morita, Moi Meng Ling

WHO Collaboration Center Reports, 18-19, Jun, 2019
Zika Fever

MOI MENG LING

74(4) 510-516, Apr, 2019 Lead authorLast authorCorresponding author
本邦産ヒトスジシマカのデングウイルス感受性

佐々木年則, 小滝徹, 田島茂, モイ・メンリン, 斎藤一三, 林昌宏, 小林大介, 伊澤晴彦, 高崎智彦, 澤邉京子

衛生動物, 70(Suppl.) 49-49, Mar, 2019
【グローバル化・温暖化と感染症対策】節足動物媒介感染症デング熱

Moi Meng Ling, 高崎智彦

小児科臨床, 70(増刊) 2148-2153, Dec, 2017
Current views of Zika virus epidemic

260(6) 528-532, Feb 11, 2017
デング熱患者間におけるフェリチン高値と臨床的および検査上の特徴との関連(Elevated ferritin and its association with clinical and laboratory characteristics among patients with dengue fever)

早川佳代子, 忽那賢志, 大曲貴夫, 竹下望, 金川修造, 山元佳, 加藤康幸, 高崎智彦, モイ・メンリン

感染症学雑誌, 90(臨増) 307-307, Mar, 2016
日本脳炎ウイルス流行株の把握と病原性・ワクチン感受性評価系の確立

中山絵里, 田島茂, 谷ヶ崎和美, 小滝徹, 富川拓海, モイ・メンリン, 林昌宏, 西條政幸, 倉根一郎, 高崎智彦

日本小児科学会雑誌, 120(2) 212-212, Feb, 2016
Recent advances in arbovirus diagnostics

28(3) 104-109, 2016
微生物ABC デングウイルスのウイルス学的特徴

モイメンリン, 高崎智彦

Up-to-date 子どもの感染症, 3(1) 18-23, Jun, 2015
Immunopathogenesis of dengue fever and dengue fever

63(3) 293-298, Mar, 2015
2014年に東京都内で捕集されたヒトスジシマカのデングウイルス保有状況調査

伊澤晴彦, 小林大介, 糸川健太郎, 津田良夫, 前川芳秀, 小川浩平, 佐々木年則, 江尻寛子, 駒形修, 冨田隆史 …

衛生動物, 66(Suppl.) 51-51, Mar, 2015
国内侵入・流行が危惧される昆虫媒介性ウイルス感染症に対する総合的対策の確立に関する研究チクングニアウイルスレプリコンの設計および抗チクングニア剤評価のための霊長類モデルに関する検討

倉根一郎, 林昌宏, 高崎智彦, 鈴木隆二, 網康至, 藤井克樹, モイメンリン, 北浦一孝, 白石顕治, ポサダス・エレラギジェルモ …

国内侵入・流行が危惧される昆虫媒介性ウイルス感染症に対する総合的対策の確立に関する研究平成26年度委託業務成果報告書, 74-78, 2015
国内侵入・流行が危惧される昆虫媒介性ウイルス感染症に対する総合的対策の確立に関する研究マーモセットを用いた再感染デング熱動物モデルの構築

モイメンリン, モイメンリン, 高崎智彦, 倉根一郎, 林昌宏, 網康至, 須崎百合子, 鈴木隆二, 白井顕治, 北浦一孝 …

国内侵入・流行が危惧される昆虫媒介性ウイルス感染症に対する総合的対策の確立に関する研究平成26年度委託業務成果報告書, 57-61, 2015

Teaching Experience

Oct, 2023 - Present

Introduction to career design: realization of own potential at a global scale (University of Tsukuba)
Jun, 2023 - Present

DDMS Advanced Summer Course: Academic Writing, Presentation & Dissertation Defense (School of International Health, Graduate School of Medicine, The University of Tokyo)
Oct, 2021 - Present

Health Science General Course (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo)
Oct, 2021 - Present

DDMS Advanced Course I & II (Graduate School) (School of International Health, Graduate School of Medicine, the University of Tokyo)
Oct, 2021 - Present

School Health (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo.)
Oct, 2021 - Present

Developmental Medical Sciences (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo)
Oct, 2021 - Present

Maternal child health (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo)
Oct, 2021 - Present

Immunology and biological defense (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo)
Oct, 2021 - Present

Infectious Disease (School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo)
Apr, 2019 - Present

Tropical Medicine Intensive Course: Dengue (School of Tropical Medicine and Global Health)
Jun, 2022 - Jun, 2022

International infectious disease control: Global threats of Arboviruses: What next in post-COVID-19 era (Tokyo University of Agriculture and Technology)
Jan, 2015 - Sep, 2021

Virology (Institute of Tropical Medicine, Nagasaki University)

Professional Memberships

Research Projects

Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2024 - Mar, 2027
Study of the development of a comprehensive method to determine pathogen epitopes for the preparation against disease X and potential applications in outbreak prediction

Japan Agency for Medical Research and Development (AMED), Jun, 2023 - Mar, 2026

Yukio Nakamura, Ryuji Suzuki, Laymyint Yoshida
Determination of miRNA biomarkers in the pathogenesis of severe dengue

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023

Moi Meng Ling
Study of neutralizing antibody repertoire in modulating dengue protection for vaccination strategies

Research Program on Emerging and Re-emerging Infectious Disease, AMED, Apr, 2019 - Mar, 2022

Moi Meng Ling
Dengue viral genetic diversity in selected populations in Myanmar

AMED eASIA Joint Research Program (eASIA), AMED, Aug, 2016 - Mar, 2020

Moi Meng Ling
Japan Initiative for Global Research Network on Infectious Diseases (J-GRID). Researches on infectious diseases in Vietnam and their application to the improvement of diagnosis, prevention and treatment

AMED, Apr, 2016 - Mar, 2020

Hirayama Kenji
Investigation of immunologic factors associated with differential disease outcomes in Zika virus infection, Vietnam

Viral Disease and Immunology Research: U.S.-Japan Cooperative Medical Sciences Program Collaborative Awards, AMED, Jun, 2018 - Mar, 2019

Moi Meng Ling
Research Program on Emerging and Re-emerging Infectious Diseases. Research project for comprehensive measures against vector-borne viral infectious diseases which has possibilities of autochthonous epidemics

AMED, Apr, 2016 - Mar, 2019

Lim Chang Kweng
Determination of the role of Fcgamma receptor in antibody-dependent enhancement of dengue virus infection

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

MOI Meng Ling, KURANE Ichiro, TAKASAKI Tomohiko, MORITA Kouichi
Determination of the role of Fcgamma receptor in antibody-dependent enhancement of dengue virus infection

JSPS, Apr, 2013 - Mar, 2016

Moi Meng Ling
Determination of the role of anti-flavivirus antibody in Dengue Infection

Young researcher (B), Grant-in-Aid for Young Scientists (B), JSPS, Apr, 2011 - Mar, 2012

Moi Meng Ling
Determination of the role of anti-flavivirus antibody in antibody-dependent enhancement infection of dengue virus

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2011 - 2012

MOI Meng ling
Development of an animal model for evaluation of Dengue vaccine

MSD Life Science Foundation

Moi Meng Ling

Social Activities

WHO Expert Group for 2019 novel coronavirus (SARS-CoV-2 Technical Network)

Lecturer, Consultant, Official expert, Planner, Logistic support, Investigator

Jan 1, 2020 - Dec 31, 2022
Deputy Head, WHO Collaborating Centre for Reference and Research on Tropical and Emerging Virus Diseases

Lecturer, Consultant, Official expert, Logistic support, Report author

Apr 1, 2015 - Sep 30, 2021

Media Coverage

Global measures against infectious disease of public health importance: Moi Meng Ling (Interview with foreign researchers)

Japan Science and Technology Agency, Feb, 2023 Internet
Towards the Future: Friendship of Japan and Malaysia

Embassy of Japan in Malaysia, Jan, 2023 Other
Meet Malaysians in Japan – Prof. Moi Meng Ling

Embassy of Japan in Malaysia, Sep, 2022 Internet
ASEAN Insights: Dr. Meng Ling Moi

Japan Science and Technology Agency, Aug, 2022 Internet

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Teaching Experience

Professional Memberships

Research Projects

Social Activities

Media Coverage

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