論文

査読有り 筆頭著者 責任著者
2011年1月

Mitogen-Activated Protein Kinase Regulated by the CLAVATA Receptors Contributes to Shoot Apical Meristem Homeostasis

PLANT AND CELL PHYSIOLOGY
  • Shigeyuki Betsuyaku
  • ,
  • Fuminori Takahashi
  • ,
  • Atsuko Kinoshita
  • ,
  • Hiroki Miwa
  • ,
  • Kazuo Shinozaki
  • ,
  • Hiroo Fukuda
  • ,
  • Shinichiro Sawa

52
1
開始ページ
14
終了ページ
29
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1093/pcp/pcq157
出版者・発行元
OXFORD UNIV PRESS

In Arabidopsis, the CLAVATA (CLV) pathway operates in the regulation of the size of the stem cell population in the shoot apical meristem (SAM). CLV3 functions as a small peptide ligand to negatively regulate the expression of the WUSCHEL (WUS) transcription factor through three major receptor kinase complexes of CLV1, CLV2-SUPPRESSOR OF LLP1-2 (SOL2)/CORYNE (CRN) and recently identified RECEPTOR-LIKE PROTEIN KINASE 2 (RPK2)/TOADSTOOL 2 (TOAD2). Aiming to understand the precise molecular details of CLV3 signaling, we investigated the contribution of phospho-signaling, potentially regulated by these kinase complexes, to the CLV pathway. We detected CLV3-triggered CLV1 phosphorylation, which is also conditioned by the rest of the CLV receptors, presumably by their direct association. Our comprehensive analysis of the activities of the respective CLV receptors on mitogen-activated protein kinases (MAPKs) suggested that the precise balanced regulation of MAPK activity by the CLV receptors is likely to be key for SAM homeostasis.

リンク情報
DOI
https://doi.org/10.1093/pcp/pcq157
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000287256400003&DestApp=WOS_CPL
ID情報
  • DOI : 10.1093/pcp/pcq157
  • ISSN : 0032-0781
  • Web of Science ID : WOS:000287256400003

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