芦野滋 (Shigeru Ashino) - マイポータル

基本情報

所属: 京都大学大学院医学研究科呼吸器内科学/オープンイノベーション機構特定講師

学位: 博士 (医学)(北海道大学)

J-GLOBAL ID: 201901016748549446
researchmap会員ID: B000377011

研究キーワード

研究分野

経歴

2021年2月 - 現在

京都大学, 大学院医学研究科呼吸器内科学/オープンイノベーション機構, 特定講師
2019年7月 - 2021年1月

東京女子医科大学, 微生物学免疫学講座, 講師
2013年11月 - 2019年6月

東京女子医科大学, 微生物学免疫学講座, 助教
2018年1月 - 2019年3月

National Jewish Health,, Division of Cell Biology, Department of Pediatrics,, Affiliated researcher (PI: Erwin W. Gelfand)
2010年4月 - 2013年10月

National Jewish Health,, Division of Cell Biology, Department of Pediatrics,, Postdoctoral fellow (PI: Erwin W. Gelfand)
2008年4月 - 2010年3月

北海道大学遺伝子病制御研究所, 免疫制御分野, 博士研究員

論文

Less airway inflammation and goblet cell metaplasia in an IL-33-induced asthma model of leptin-deficient obese mice.

Atsushi Kurokawa, Mitsuko Kondo, Ken Arimura, Shigeru Ashino, Etsuko Tagaya

Respiratory research 22(1) 166-166 2021年6月1日
Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children.

Meiqin Wang, Matthew J Strand, Bruce J Lanser, Carah Santos, Kreso Bendelja, Jennifer Fish, Elizabeth A Esterl, Shigeru Ashino, Jordan K Abbott, Vijaya Knight …

PloS one 15(6) e0233563 2020年
Effect of Cholecalciferol in Food Allergy Mouse Model Is Associated with Decrease of CD69⁺ CD4⁺ T Cells.

Zaim E, Ashino S, Osaka T, Yanagisawa N, Yagi J

Journal of nutritional science and vitaminology 65(2) 113-122 2019年査読有り
Activation of p70S6 Kinase-1 in Mesenchymal Stem Cells Is Essential to Lung Tissue Repair.

Katsuyuki Takeda, Fangkun Ning, Joanne Domenico, Masakazu Okamoto, Shigeru Ashino, Sang-Ha Kim, Yi Yeong Jeong, Yoshiki Shiraishi, Naohiro Terada, Everett Rand Sutherland …

Stem cells translational medicine 7(7) 551-558 2018年7月査読有り
Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation.

Katsuyuki Takeda, Tracy L Webb, Fangkun Ning, Yoshiki Shiraishi, Daniel P Regan, Lyndah Chow, Mia J Smith, Shigeru Ashino, Amanda M Guth, Sophie Hopkins …

Journal of immunology (Baltimore, Md. : 1950) 200(4) 1261-1269 2018年2月15日査読有り
Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge

Katsuyuki Takeda, Yoshiki Shiraishi, Shigeru Ashino, Junyan Han, Yi Jia, Meiqin Wang, Nancy A. Lee, James J. Lee, Erwin W. Gelfand

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 135(2) 451-U610 2015年2月査読有り
JNK2 Regulates the Functional Plasticity of Naturally Occurring T Regulatory Cells and the Enhancement of Lung Allergic Responses

Anthony Joetham, Michaela Schedel, Katsuyuki Takeda, Yi Jia, Shigeru Ashino, Azzeddine Dakhama, Anna Lluis, Masakazu Okamoto, Erwin W. Gelfand

JOURNAL OF IMMUNOLOGY 193(5) 2238-2247 2014年9月査読有り
Janus kinase 1/3 signaling pathways are key initiators of T(H)2 differentiation and lung allergic responses

Shigeru Ashino, Katsuyuki Takeda, Hui Li, Vanessa Taylor, Anthony Joetham, Polly R. Pine, Erwin W. Gelfand

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 133(4) 1162-+ 2014年4月査読有り
Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation

Meiqin Wang, Masakazu Okamoto, Joanne Domenico, Junyan Han, Shigeru Ashino, Yoo Seob Shin, Erwin W. Gelfand

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 130(4) 932-+ 2012年10月査読有り
IFN-γ elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model.

Kobayashi M, Ashino S, Shiohama Y, Wakita D, Kitamura H, Nishimura T, ly contributing auth

European journal of immunology 42(2) 393-402 2012年2月査読有り
A T(h)17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-gamma production in order to induce airway hyperresponsiveness

Shigeru Ashino, Daiko Wakita, Yasuo Shiohama, Yoichiro Iwakura, Kenji Chamoto, Takayuki Ohkuri, Hidemitsu Kitamura, Takashi Nishimura

INTERNATIONAL IMMUNOLOGY 22(6) 503-513 2010年6月査読有り
IFN-gamma-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model

Daiko Wakita, Kenji Chamoto, Takayuki Ohkuri, Yoshinori Narita, Shigeru Ashino, Kentaro Sumida, Hiroyoshi Nishikawa, Hiroshi Shiku, Yuji Togashi, Hidemitsu Kitamura …

CARCINOGENESIS 30(8) 1408-1415 2009年8月査読有り
Osteopontin is involved in migration of eosinophils in asthma

A. Takahashi, M. Kurokawa, S. Konno, K. Ito, S. Kon, S. Ashino, T. Nishimura, T. Uede, N. Hizawa, S-K Huang …

CLINICAL AND EXPERIMENTAL ALLERGY 39(8) 1152-1159 2009年8月査読有り
Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells

Kenji Chamoto, Tsuguhide Takeshima, Daiko Wakita, Takayuki Ohkuri, Shigeru Ashino, Tokuhiko Omatsu, Hiroki Shirato, Hidemitsu Kitamura, Yuji Togashi, Takashi Nishimura

CANCER SCIENCE 100(5) 934-939 2009年5月査読有り
CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific T(h)2-cell migration into lung

Shigeru Ashino, Daiko Wakita, Yue Zhang, Kenji Chamoto, Hidemitsu Kitamura, Takashi Nishimura

INTERNATIONAL IMMUNOLOGY 20(2) 259-266 2008年2月査読有り
MS11-3 Th1およびTh17依存的気道アレルギーにおける気道過敏性上昇機構の解明(気管支喘息-病態生理,第58回日本アレルギー学会秋季学術大会)

芦野滋, 小林稔, 茶本健司, 冨樫裕二, 北村秀光, 西村孝司

アレルギー 57(9) 1418-1418 2008年
Blocking of IL-6 signaling pathway prevents CD4(+) T cell-mediated colitis in a T(h)17-independent manner

Daisuke Noguchi, Daiko Wakita, Masaki Tajima, Shigeru Ashino, Yoichiro Iwakura, Yue Zhang, Kenji Chamoto, Hidemitsu Kitamura, Takashi Nishimura

INTERNATIONAL IMMUNOLOGY 19(12) 1431-1440 2007年12月査読有り
STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation

A Hoshino, T Tsuji, J Matsuzaki, T Jinushi, S Ashino, T Teramura, K Chamoto, Y Tanaka, Y Asakura, T Sakurai …

INTERNATIONAL IMMUNOLOGY 16(10) 1497-1505 2004年10月査読有り