論文

査読有り 筆頭著者 責任著者
2017年4月

A modification of the PHYLIP program: A solution for the redundant cluster problem, and an implementation of an automatic bootstrapping on trees inferred from original data

MOLECULAR PHYLOGENETICS AND EVOLUTION
  • Makoto K. Shimada
  • ,
  • Tsunetoshi Nishida

109
開始ページ
409
終了ページ
414
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ympev.2017.02.012
出版者・発行元
ACADEMIC PRESS INC ELSEVIER SCIENCE

Felsenstein's PHYLIP package of molecular phylogeny tools has been used globally since 1980. The programs are receiving renewed attention because of their character-based user interface, which has the advantage of being scriptable for use with large-scale data studies based on super-computers or massively parallel computing clusters. However, occasionally we found, the PHYLIP Consense program output text file displays two or more divided bootstrap values for the same cluster in its result table, and when this happens the output Newick tree file incorrectly assigns only the last value to that cluster that disturbs correct estimation of a consensus tree. We ascertained the cause of this aberrant behavior in the bootstrapping calculation. Our rewrite of the Consense program source code outputs bootstrap values, without redundancy, in its result table, and a Newick tree file with appropriate, corresponding bootstrap values. Furthermore, we developed an add-on program and shell script, add_bootstrap.pl and fasta2tre_bs.bsh, to generate a Newick tree containing the topology and branch lengths inferred from the original data along with valid bootstrap values, and to actualize the automated inference of a phylogenetic tree containing the originally inferred topology and branch lengths with bootstrap values, from multiple unaligned sequences, respectively. These programs can be downloaded at: https://github.com/ShimadaMK/PHYLIP_enhance/. (C) 2017 Elsevier Inc. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/j.ympev.2017.02.012
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28232198
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000398007300035&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.ympev.2017.02.012
  • ISSN : 1055-7903
  • eISSN : 1095-9513
  • PubMed ID : 28232198
  • Web of Science ID : WOS:000398007300035

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