2009 - 2011
Why do not obese bears suffer fatty liver?-Study on mechanism for accumulation of body fat during pre-hibernation period
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
- Grant number
- 21580355
- Japan Grant Number (JGN)
- JP21580355
- Authorship
- Collaborating Investigator(s) (not designated on Grant-in-Aid)
- Grant amount
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- (Total)
- 4,940,000 Japanese Yen
- (Direct funding)
- 3,800,000 Japanese Yen
- (Indirect funding)
- 1,140,000 Japanese Yen
- Grant type
- Competitive
This study was conducted in Ani Mataginosato Bear Park, Kitaakita-shi, Akita Prefecture in order to know why obese bears do not suffer fatty liver even though they get 30-40% fat of body weight and to investigate a feature mechanism for accumulation of body fat. Under anesthetized condition, measurements of blood concentrations of carbohydrate and fat, intravenous glucose tolerance tests and adipose tissue biopsies were performed for this study. As results, it is concluded that increase of body fat accumulation during pre-hibernation period is controlled by physiological and metabolic mechanism as well as hyperphagia in Japanese black bears
- Link information
- ID information
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- Grant number : 21580355
- Japan Grant Number (JGN) : JP21580355