論文

国際誌
2019年

Successful Treatment of Gastrosplenic Fistula Arising from Diffuse Large B-Cell Lymphoma with Chemotherapy: Two Case Reports.

Case reports in oncology
  • Makoto Saito
  • ,
  • Kencho Miyashita
  • ,
  • Yosuke Miura
  • ,
  • Shinpei Harada
  • ,
  • Reiki Ogasawara
  • ,
  • Koh Izumiyama
  • ,
  • Akio Mori
  • ,
  • Masanori Tanaka
  • ,
  • Masanobu Morioka
  • ,
  • Takeshi Kondo

12
2
開始ページ
376
終了ページ
383
記述言語
英語
掲載種別
DOI
10.1159/000500505

Gastrosplenic fistula (GSF) is a rare condition arising from gastric or splenic lymphomas. Surgical resection is the most common treatment, as described in previous reports. We report two cases of GSF in diffuse large B-cell lymphoma (DLBCL) patients that were successfully treated with chemotherapy and irradiation without surgical resection. Case 1 was of a 63-year-old man who had primary gastric DLBCL with a large lesion outside the stomach wall, leading to a spontaneous fistula in the spleen. Case 2 was of a 59-year-old man who had primary splenic DLBCL, which proliferated and infiltrated directly into the stomach. In both cases, chemotherapy comprising rituximab + dose-adjusted EPOCH regimen (etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin) was administered. Case 1 had significant bleeding from the lesion of the stomach during the treatment cycle; however, endoscopic hemostasis was achieved. Case 2 developed a fistula between the stomach and the spleen following therapeutic chemotherapy; however, no complications related to the fistula were observed thereafter. In both cases, irradiation was administered, and complete remission was achieved.

リンク情報
DOI
https://doi.org/10.1159/000500505
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31182954
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547279
ID情報
  • DOI : 10.1159/000500505
  • PubMed ID : 31182954
  • PubMed Central 記事ID : PMC6547279

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