2010年3月
Reward acts as a signal to control delay-period activity in delayed-response tasks
NEUROREPORT
- ,
- ,
- 巻
- 21
- 号
- 5
- 開始ページ
- 367
- 終了ページ
- 370
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1097/WNR.0b013e32833776a3
- 出版者・発行元
- LIPPINCOTT WILLIAMS & WILKINS
Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-delivery were examined by analyzing single-neuron activity recorded in the primate dorsolateral prefrontal cortex. Among neurons that showed delay-period activity, 34% showed inhibition of this activity in response to unexpected reward-delivery. The delay-period activity of these neurons was affected by the expectation of reward-delivery. The strength of the reward signal in controlling the delay-period activity is related to the strength of the effect of reward information on the delay-period activity. These results indicate that reward-delivery acts as a signal to control delay-period activity. NeuroReport 21:367-370 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
- リンク情報
- ID情報
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- DOI : 10.1097/WNR.0b013e32833776a3
- ISSN : 0959-4965
- Web of Science ID : WOS:000276137500010