論文

査読有り 国際誌
2016年7月1日

Regionally distinct cutaneous afferent populations contribute to reflex modulation evoked by stimulation of the tibial nerve during walking.

Journal of neurophysiology
  • Tsuyoshi Nakajima
  • ,
  • Shinya Suzuki
  • ,
  • Genki Futatsubashi
  • ,
  • Hiroyuki Ohtsuska
  • ,
  • Rinaldo A Mezzarane
  • ,
  • Trevor S Barss
  • ,
  • Taryn Klarner
  • ,
  • E Paul Zehr
  • ,
  • Tomoyoshi Komiyama

116
1
開始ページ
183
終了ページ
90
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1152/jn.01011.2015

During walking, cutaneous reflexes in ankle flexor muscle [tibialis anterior (TA)] evoked by tibial nerve (TIB) stimulation are predominantly facilitatory at early swing phase but reverse to suppression at late swing phase. Although the TIB innervates a large portion of the skin of the foot sole, the extent to which specific foot-sole regions contribute to the reflex reversals during walking remains unclear. Therefore, we investigated regional cutaneous contributions from discrete portions of the foot sole on reflex reversal in TA following TIB stimulation during walking. Summation effects on reflex amplitudes, when applying combined stimulation from foot-sole regions with TIB, were examined. Middle latency responses (MLRs; 70-120 ms) after TIB stimulation were strongly facilitated during the late stance to mid-swing phases and reversed to suppression just before heel (HL) strike. Both forefoot-medial (f-M) and forefoot-lateral stimulation in the foot sole induced facilitation during stance-to-swing transition phases, but HL stimulation evoked suppression during the late stance to the end of swing phases. At the stance-to-swing transition, a summation of MLR amplitude occurred only for combined f-M&TIB stimulation. However, the same was not true for the combined HL&TIB stimulation. At the swing-to-stance transition, there was a suppressive reflex summation only for HL&TIB stimulation. In contrast, this summation was not observed for the f-M&TIB stimulation. Our results suggest that reflex reversals evoked by TIB stimulation arise from distinct reflex pathways to TA produced by separate afferent populations innervating specific regions of the foot sole.

リンク情報
DOI
https://doi.org/10.1152/jn.01011.2015
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27075541
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961762
ID情報
  • DOI : 10.1152/jn.01011.2015
  • ISSN : 0022-3077
  • PubMed ID : 27075541
  • PubMed Central 記事ID : PMC4961762

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