2018年1月1日
Ascosteroside D, a new mitochondrial respiration inhibitor discovered by pesticidal screening using insect ADP/ATP carrier protein-expressing Saccharomyces cerevisiae
Journal of Antibiotics
- 巻
- 71
- 号
- 1
- 開始ページ
- 146
- 終了ページ
- 148
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1038/ja.2017.118
- 出版者・発行元
- Nature Publishing Group
A new lanostane-type triterpenoid, ascosteroside D, was isolated from a fungus, Aspergillus sp. FKI-6682. It inhibited insect ADP/ATP carrier protein (AAC)-expressing Saccharomyces cerevisiae in glycerol-containing medium, but did not inhibit Δaac S. cerevisiae in glucose-containing medium. It is hypothesized that ascosteroside D inhibits ATP production in mitochondria.
- リンク情報
- ID情報
-
- DOI : 10.1038/ja.2017.118
- ISSN : 1881-1469
- ISSN : 0021-8820
- SCOPUS ID : 85040236566