論文

査読有り
2013年10月

Intravenous Tissue Plasminogen Activator Therapy for an Acute Ischemic Stroke Patient with Later Diagnosed Unilateral Moyamoya Syndrome

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
  • Shota Yokoyama
  • ,
  • Yasuhiro Manabe
  • ,
  • Daiki Fujii
  • ,
  • Yasuko Ikeda-Sakai
  • ,
  • Hisashi Narai
  • ,
  • Nobuhiko Omori
  • ,
  • Koji Abe

22
7
開始ページ
1190
終了ページ
1192
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jstrokecerebrovasdis.2012.06.011
出版者・発行元
ELSEVIER SCIENCE BV

We report the use of intravenous tissue plasminogen activator (t-PA) therapy in a 38-year-old patient who was later diagnosed with unilateral moyamoya syndrome. The patient had a sudden onset of unconsciousness, vomiting, dysarthria, and tetraparesis. A neurologic examination revealed consciousness disturbance, right central facial nerve palsy, dysarthria, and tetraparesis with bilateral exotropia and horizontal gaze palsy. A magnetic resonance imaging scan on admission did not reveal fresh cerebral infarction or hemorrhage, but magnetic resonance angiography revealed severe stenosis at the terminal portion of left internal carotid artery, the anterior cerebral arteries, and the right vertebral artery. We suspected infarction of brain stem. The patient was treated with intravenous t-PA approximately 2.5 hours after onset, and the patient demonstrated a remarkable recovery 1 day after onset and had only a minimal deficit at discharge (12 days after onset). Cerebral angiography 7 days after onset confirmed the diagnosis of moyamoya disease. The present case suggests that therapeutic intravenous t-PA may be applicable for an acute ischemic stroke patient coexisting with moyamoya disease after careful evaluation and discussion with patient and family.

リンク情報
DOI
https://doi.org/10.1016/j.jstrokecerebrovasdis.2012.06.011
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/22832175
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000325874200087&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.jstrokecerebrovasdis.2012.06.011
  • ISSN : 1052-3057
  • eISSN : 1532-8511
  • PubMed ID : 22832175
  • Web of Science ID : WOS:000325874200087

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