2022年9月30日
Effect of Neonicotinoid Pesticides on Japanese Water Systems: Review with Focus on Reproductive Toxicity
International Journal of Molecular Sciences
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- 巻
- 23
- 号
- 19
- 開始ページ
- 11567
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3390/ijms231911567
- 出版者・発行元
- MDPI
Neonicotinoid pesticides (NPs) are neurotoxic substances. They are highly effective as insecticides owing to their water solubility, permeability, and long-lasting activity. These molecules are structurally similar to nicotine and act as nicotinic acetylcholine receptor agonists. The administration of NPs to experimental animals reportedly causes neuromuscular and reproductive disorders. Moreover, recently reported problems caused by NPs include damage to land-dwelling creatures (such as mammals and birds), hydrobiology, and ecosystems. This review summarizes the recent reports on NP concentrations detected in river systems in several Japanese regions. These values were lower than the environmental standard values; however, seasonal variations were observed. Furthermore, reports on NP-induced testicular and ovarian toxicity were examined, revealing that the mechanism of injury is mainly driven by oxidative stress. The use of NPs is declining worldwide, except in Japan; therefore, continuous monitoring remains necessary.
- リンク情報
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- DOI
- https://doi.org/10.3390/ijms231911567 本文へのリンクあり
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/36232869
- PubMed Central
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570366
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000867770600001&DestApp=WOS_CPL
- URL
- https://www.mdpi.com/1422-0067/23/19/11567 本文へのリンクあり
- ID情報
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- DOI : 10.3390/ijms231911567
- ISSN : 1422-0067
- eISSN : 1422-0067
- ORCIDのPut Code : 120191792
- PubMed ID : 36232869
- PubMed Central 記事ID : PMC9570366
- Web of Science ID : WOS:000867770600001