宮本将平 (Shohei Miyamoto) - マイポータル

基本情報

所属: 東京慈恵会医科大学総合医科学研究センター悪性腫瘍治療研究部

J-GLOBAL ID: 202401016302693110
researchmap会員ID: R000072640

論文

Coxsackievirus A11 is an immunostimulatory oncolytic virus that induces complete tumor regression in a human non-small cell lung cancer.

Akira Sakamoto, Hiroyuki Inoue, Shohei Miyamoto, Shun Ito, Yasushi Soda, Kenzaburo Tani

Scientific reports 13(1) 5924-5924 2023年4月12日
Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B3.

Miyako Sagara, Shohei Miyamoto, Shun Itoh, Yasushi Soda, Kenzaburo Tani

Anticancer research 41(1) 81-89 2021年1月
A pilot study to establish human T-cell leukemia virus type 1 (HTLV-1) carrier model using common marmoset (Callithrix jacchus).

Lisa Hirose, Takafumi Hiramoto, Yamin Tian, Hiroshi Kohara, Seiichiro Kobayashi, Etsuko Nagai, Tamami Denda, Yukihisa Tanaka, Yasunori Ota, Liao Jiyuan …

Journal of medical primatology 49(2) 86-94 2020年4月
Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells.

Takafumi Hiramoto, Maino Tahara, Jiyuan Liao, Yasushi Soda, Yoshie Miura, Ryo Kurita, Hiroshi Hamana, Kota Inoue, Hiroshi Kohara, Shohei Miyamoto …

Molecular therapy : the journal of the American Society of Gene Therapy 28(1) 129-141 2020年1月8日
Photocontrollable mononegaviruses.

Maino Tahara, Yuto Takishima, Shohei Miyamoto, Yuichiro Nakatsu, Kenji Someya, Moritoshi Sato, Kenzaburo Tani, Makoto Takeda

Proceedings of the National Academy of Sciences of the United States of America 116(24) 11587-11589 2019年6月11日
KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells.

Hiroshi Kohara, Taiju Utsugisawa, Chika Sakamoto, Lisa Hirose, Yoshie Ogawa, Hiromi Ogura, Ai Sugawara, Jiyuan Liao, Takako Aoki, Takuya Iwasaki …

Experimental hematology 73 25-37 2019年5月
Extremely Low Organ Toxicity and Strong Antitumor Activity of miR-34-Regulated Oncolytic Coxsackievirus B3.

Yang Jia, Shohei Miyamoto, Yasushi Soda, Yuto Takishima, Miyako Sagara, Jiyuan Liao, Lisa Hirose, Yasuki Hijikata, Yoshie Miura, Kenichiro Hara …

Molecular therapy oncolytics 12 246-258 2019年3月29日
A Novel Combination Therapy for Human Oxaliplatin-resistant Colorectal Cancer Using Oxaliplatin and Coxsackievirus A11.

Beibei Wang, Hisanobu Ogata, Yuto Takishima, Shohei Miyamoto, Hiroyuki Inoue, Masaki Kuroda, Kazunari Yamada, Yasuki Hijikata, Mutsunori Murahashi, Hiroyuki Shimizu …

Anticancer research 38(11) 6121-6126 2018年11月
[Oncolytic coxsackievirus therapy as an immunostimulator].

Shohei Miyamoto, Miyako Sagara, Hiroshi Kohara, Kenzaburo Tani

[Rinsho ketsueki] The Japanese journal of clinical hematology 58(8) 977-982 2017年
A novel, polymer-coated oncolytic measles virus overcomes immune suppression and induces robust antitumor activity.

Kaname Nosaki, Katsuyuki Hamada, Yuto Takashima, Miyako Sagara, Yumiko Matsumura, Shohei Miyamoto, Yasuki Hijikata, Toshihiko Okazaki, Yoichi Nakanishi, Kenzaburo Tani

Molecular therapy oncolytics 3 16022-16022 2016年
TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells.

Megumi Narusawa, Hiroyuki Inoue, Chika Sakamoto, Yumiko Matsumura, Atsushi Takahashi, Tomoko Inoue, Ayumi Watanabe, Shohei Miyamoto, Yoshie Miura, Yasuki Hijikata …

Cancer immunology research 2(6) 568-80 2014年6月
Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma.

Shohei Miyamoto, Hiroyuki Inoue, Takafumi Nakamura, Meiko Yamada, Chika Sakamoto, Yasuo Urata, Toshihiko Okazaki, Tomotoshi Marumoto, Atsushi Takahashi, Koichi Takayama …

Cancer research 72(10) 2609-21 2012年5月15日
Enhanced antitumor effects of an engineered measles virus Edmonston strain expressing the wild-type N, P, L genes on human renal cell carcinoma.

Xin Meng, Takafumi Nakamura, Toshihiko Okazaki, Hiroyuki Inoue, Atsushi Takahashi, Shohei Miyamoto, Gaku Sakaguchi, Masatoshi Eto, Seiji Naito, Makoto Takeda …

Molecular therapy : the journal of the American Society of Gene Therapy 18(3) 544-51 2010年3月

MISC

MicroRNA-Targeted Oncolytic Virotherapy for Triple-Negative Breast Cancer

Shohei Miyamoto, Shun Ito, Miyako Sagara, Yasushi Soda, Ken-ichiro Hara, Akira Sakamoto, Jiyuan Liao, Ken Kodama, Kenzaburo Tani

CANCER SCIENCE 112 932-932 2021年2月
Oncolytic Coxsackievirus Therapy as an Immunostimulator

Ken-ichiro Hara, Shohei Miyamoto, Miyako Sagara, Lisa Hirose-Yotsuya, Akira Sakamoto, Yasushi Soda, Kenzaburo Tani

MOLECULAR THERAPY 28(4) 163-163 2020年4月
Non-Integrating Measles Virus Vector is a Promising Tool for Naive iPSCs Generation and T-cell Engineering

Jiyuan Liao, Yasushi Soda, Ai Sugawara, Yoshie Miura, Takafumi Hiramoto, Maino Tahara, Yuto Takishima, Shohei Miyamoto, Makoto Takeda, Kenzaburo Tani

MOLECULAR THERAPY 28(4) 531-531 2020年4月
F-Deletion Non-Integrating Measles Virus Vector: A Promising Tool for T-Cell Engineering and Naive iPSCs Generation

Jiyuan Liao, Yasushi Soda, Ai Sugawara, Yoshie Miura, Takafumi Hiramoto, Maino Tahara, Yuto Takishima, Shohei Miyamoto, Makoto Takeda, Kenzaburo Tani

BLOOD 134 2019年11月
Analysis of Human iPSCs Generated by a Non-Integrating Measles Virus Vector

Jiyuan Liao, Yasushi Soda, Ai Sugawara, Yoshie Miura, Takafumi Hiramoto, Maino Tahara, Yuto Takishima, Yasuki Hijikata, Shohei Miyamoto, Makoto Takeda …

MOLECULAR THERAPY 27(4) 418-418 2019年4月
Novel Recombinant Coxsackievirus B3 Infection Elicits Robust Oncolytic Activity Against Human Non-Small Lung Cancer and Triple-Negative Breast Cancer

Miyako Sagara, Yuto Takishima, Shohei Miyamoto, Hiroyuki Shimizu, Yoichi Nakanishi, Kenzaburo Tani

MOLECULAR THERAPY 24 S162-S162 2016年5月
Novel Polymer-Coated Stealth Oncolytic Measles Virus Overcame Immune Suppression and Induced Stronger Antitumor Activity

Kaname Nosaki, Katsuyuki Hamada, Yuto Takishima, Miyako Sagara, Yumiko Matsumura, Shohei Miyamoto, Michiyo Okada, Yasuki Hijikata, Toshihiko Okazaki, Kazunari Yamada …

MOLECULAR THERAPY 23 S251-S251 2015年5月
Coxsackievirus A11 Induces Robust Oncolytic Activity Against Human Non-Small Cell Lung Cancer Cells With Immunostimulatory Properties

Miyako Sagara, Hiroyuki Inoue, Masaki Kuroda, Shohei Miyamoto, Hisanobu Ogata, Yuki Nakano, Beibei Wang, Yuto Takishima, Kazunari Yamada, Hiroyuki Shimizu …

MOLECULAR THERAPY 23 S171-S172 2015年5月
IMMUNE AND GENE THERAPY AS AN EMERGING CANCER TREATMENT

Kenzaburo Tani, Yasuki Hijikata, Mutsunori Murahashi, Shohei Miyamoto, Hiroyuki Inoue, Yoshihiro Tanaka, Shinichi Kobayashi, Toshihisa Tsuruta, Kazunari Yamada, Toshihiko Okazaki

ANNALS OF ONCOLOGY 25 2014年10月
Therapeutic Vaccination With Irradiated GM-CSF Gene-Transduced Cancer Side Population Cells Effectively Suppress Tumor Growth and Lung Metastasis

Chika Sakamoto, Hiroyuki Inoue, Megumi Narusawa, Yumiko Matsumura, Shohei Miyamoto, Makoto Inoue, Koichi Takayama, Mamoru Hasegawa, Yoichi Nakanishi, Kenzaburo Tani

MOLECULAR THERAPY 22 S164-S164 2014年5月
Enhanced Antitumor Effects of an Engineered Measles Virus Edmonston Strain Expressing the Wild-type N, P, L Genes on Human Renal Cell Carcinoma (vol 18, pg 544, 2010)

Xin Meng, Takafumi Nakamura, Toshihiko Okazaki, Hiroyuki Inoue, Atsushi Takahashi, Shohei Miyamoto, Gaku Sakaguchi, Masatoshi Eto, Seiji Naito, Makoto Takeda …

MOLECULAR THERAPY 18(6) 1248-1248 2010年6月

共同研究・競争的資金等の研究課題

がん指向性リポソームによる遺伝子制御を利用した膵癌腫瘍溶解性ウイルス療法の開発

日本学術振興会科学研究費助成事業基盤研究(C) 2023年4月 - 2027年3月

百田禎郎, 村橋睦了, 宮本将平, 坂下裕紀
腫瘍溶解ウイルス併用免疫療法による進行再発食道癌に対する革新的治療の開発

日本学術振興会科学研究費助成事業基盤研究(C) 2023年4月 - 2026年3月

谷島雄一郎, 村橋睦了, 宮本将平, 増田隆洋, 矢野文章, 百田禎郎
革新的麻疹ウイルスベクターを用いた強力で安価な新規CAR-T療法の開発

日本学術振興会科学研究費助成事業基盤研究(B) 2021年4月 - 2024年3月

谷憲三朗, 曽田泰, 宮本将平
メチオニン分解酵素遺伝子搭載によるバイスタンダー効果誘導腫瘍溶解性ウィルスの開発

日本学術振興会科学研究費助成事業挑戦的研究(萌芽) 2020年7月 - 2023年3月

曽田泰, 宮本将平, 廖紀元
ゲノム編集ハイスループットノックアウトによる腫瘍溶解性ウイルスの細胞傷害性の解明

日本学術振興会科学研究費助成事業若手研究 2019年4月 - 2023年3月

宮本将平
遺伝子組換えによる高い安全性と抗腫瘍効果に優れる新規腫瘍溶解性ウイルス療法の開発

日本学術振興会科学研究費助成事業若手研究(B) 2016年4月 - 2019年3月

宮本将平