堀田彰一朗 (Shoichiro Horita) - マイポータル

基本情報

所属: 福島県立医科大学糖尿病内分泌代謝内科学講座講師

学位: 博士（農学）(東京大学)

研究者番号: 50770640
J-GLOBAL ID: 202001016151561772
researchmap会員ID: R000012265

2007年3月東京大学農学部二類応用生命化学専修卒業

2009年3月東京大学大学院農学生命科学研究科応用生命化学専攻博士前期課程修了

2011年 4月日本学術振興会特別研究員（DC2）

2012年 3月東京大学大学院農学生命科学研究科応用生命化学専攻博士後期課程修了博士(農学)取得 (田之倉優教授)

2012年 4月英国オックスフォード大学生理学講座博士研究員（Prof. Frances Ashcroft）

　　　　 (英国オックスフォード大学化学科博士研究員兼務（Prof. Christopher Schofield）

　　　　　 2013年 4月日本学術振興会海外特別研究員

2015年 4月京都大学大学院医学研究科博士研究員（PD）(岩田想教授)

2018年 4月福島県立医科大学医学部病態制御薬理医学（旧薬理学）講座講師（下村健寿教授）

2024年 4月福島県立医科大学医学部糖尿病内分泌代謝内科学講座講師（島袋充生教授）　

論文

Kir6.2 channel activity is regulated by interaction of transmembrane domains 1 and 2 through I167 in the bundle-crossing gate.

Ryoko Kawashima, Charlotte Meller, Manabu Suzuki, Shigeki Kato, Shoichiro Horita, Shizu Hidema, Shingen Misaka, Mitsuaki Hosoya, Hayato Go, Kazuto Kobayashi …

Physiological reports 13(15) e70481 2025年8月
Canagliflozin-Induced Renal Glutathione Distribution Mapping in non-Diabetic Male Rat Kidneys

Guy Watanabe, Shoichiro Horita, Reika Flora Moriya, Yusuke Masuishi, Shingen Misaka, Shu Taira, Kenju Shimomura, Michio Shimabukuro, Junichiro James Kazama

Physiological reports 13(7) 2025年4月13日責任著者
Peripheral Dopamine Suppression and Elevated Cystatin C in Early Diabetic Nephropathy in Spontaneously Diabetic Rats.

Shoichiro Horita, Guy Watanabe, Shingen Misaka, Shu Taira, Mamoru Satoh, Yuko Maejima, Kenju Shimomura, Michio Shimabukuro, Junichiro James Kazama, Shuichi Shigetomi

American journal of physiology. Renal physiology 2024年8月1日筆頭著者責任著者
ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.

Sho Koyasu, Shoichiro Horita, Keisuke Saito, Minoru Kobayashi, Hiroshi Ishikita, Christalle Ct Chow, Gouki Kambe, Shigeto Nishikawa, Toshi Menju, Akiyo Morinibu …

EMBO reports e202154042 2022年11月7日
Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia.

Yuko Maejima, Shoichiro Horita, Shoko Yokota, Megumi Yamachi, Masaru Shimizu, Tomoyuki Ono, Zhiquian Yu, Hiroaki Tomita, Kenju Shimomura

Molecular and cellular neurosciences 120 103734-103734 2022年5月1日
Identification of oxytocin receptor activating chemical components from traditional Japanese medicines.

Yuko Maejima, Shoichiro Horita, Shoko Yokota, Tomoyuki Ono, Peter Proks, Hiromi Yoshida-Komiya, Yoichi Ueta, Katsuhiko Nishimori, Shingen Misaka, Kenju Shimomura

Journal of food and drug analysis 29(4) 653-675 2021年12月15日
Comparative Analysis of Derivatization Reagents for Catecholamines and Amino Acids

Shu Taira, Akari Ikeda, Shoko Kobayashi, Hitomi Shikano, Ryuzoh Ikeda, Yuko Maejima, Shoichiro Horita, Jun Yokoyama, Kenju Shimomura

APPLIED SCIENCES-BASEL 11(13) 2021年7月
The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity.

Yuko Maejima, Shoko Yokota, Masaru Shimizu, Shoichiro Horita, Daisuke Kobayashi, Akihiro Hazama, Kenju Shimomura

Nutrition & metabolism 18(1) 58-58 2021年6月7日
Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle.

Shoichiro Horita, Tomoyuki Ono, Saul Gonzalez-Resines, Yuko Ono, Megumi Yamachi, Songji Zhao, Carmen Domene, Yuko Maejima, Kenju Shimomura

Scientific reports 11(1) 6668-6668 2021年3月23日筆頭著者責任著者
Soluble interleukin-2 receptor as a predictive and prognostic marker for patients with familial breast cancer

Kenji Gonda, Shoichiro Horita, Yuko Maejima, Seiichi Takenoshita, Kenju Shimomura

Science Progress 104(3) 2021年
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.

Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata …

Nature communications 11(1) 4160-4160 2020年8月19日
Oral oxytocin delivery with proton pump inhibitor pretreatment decreases food intake.

Yuko Maejima, Shoichiro Horita, Ayano Otsuka, Shizu Hidema, Katsuhiko Nishimori, Kenju Shimomura

Peptides 128 170312-170312 2020年6月
A Targeted Genetic Association Study of the Rare Type of Osteomyelitis.

H Yahara, S Horita, S Yanamoto, Y Kitagawa, T Asaka, T Yoda, K Morita, Y Michi, M Takechi, H Shimasue …

Journal of dental research 99(3) 271-276 2020年3月
TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice.

Yuko Ono, Yuko Maejima, Masafumi Saito, Kazuho Sakamoto, Shoichiro Horita, Kenju Shimomura, Shigeaki Inoue, Joji Kotani

Scientific reports 10(1) 694-694 2020年1月20日
Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding.

Koji Nagata, Akitoshi Okada, Jun Ohtsuka, Takatoshi Ohkuri, Yusuke Akama, Yukari Sakiyama, Erika Miyazaki, Shoichiro Horita, Tsutomu Katayama, Tadashi Ueda …

Journal of biochemistry 167(1) 1-14 2020年1月1日
Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells.

Ryota Imai, Shoichiro Horita, Yuko Ono, Keisuke Hagihara, Masaru Shimizu, Yuko Maejima, Kenju Shimomura

BioResearch open access 9(1) 116-120 2020年
Early life high-fat diet exposure evokes normal weight obesity.

Yuko Maejima, Shoko Yokota, Shoichiro Horita, Kenju Shimomura

Nutrition & metabolism 17 48-48 2020年
Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.

Kenji Gonda, Takanori Akama, Takayuki Nakamura, Eiko Hashimoto, Naomi Kyoya, Yuichi Rokkaku, Yuko Maejima, Shoichiro Horita, Kazunoshin Tachibana, Noriko Abe …

Journal of medical case reports 13(1) 381-381 2019年12月24日
The hypothalamus to brainstem circuit suppresses late-onset body weight gain.

Yuko Maejima, Shigeki Kato, Shoichiro Horita, Yoichi Ueta, Seiichi Takenoshita, Kazuto Kobayashi, Kenju Shimomura

Scientific reports 9(1) 18360-18360 2019年12月4日
Association between cognitive impairment patient with solid cancer and insulin resistance.

Kenji Gonda, Kenji Yaginuma, Yuichi Rokkaku, Shoichiro Horita, Yuko Maejima, Kenju Shimomura

BMC research notes 12(1) 705-705 2019年10月28日