2020年2月7日
Additive Manufacturing of Micromanipulator Mounted on a Glass Capillary for Biological Applications
Micromachines
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- 巻
- 11
- 号
- 2
- 開始ページ
- 174
- 終了ページ
- 174
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3390/mi11020174
- 出版者・発行元
- MDPI AG
In this study, a three-dimensional (3D) micromanipulator mounted on a glass capillary is developed for handling biological samples, such as multicellular spheroids and embryos. To fabricate the micromanipulator, we developed an additive manufacturing system based on high-resolution microstereolithography using a 405-nm blue laser. The fabrication system makes it possible to fabricate 3D microstructures on a glass capillary with 2.5 µm lateral resolution and 25 µm layer thickness. We also demonstrated the capture and release of a spheroid with the micromanipulator fabricated using our additive manufacturing system. We showed that spheroids can be easily handled by a simple operation with minimal damage using a cage-like multiple finger structure. Additive manufacturing of tailor-made micromanipulators mounted on a glass capillary will be useful in biological and tissue engineering research.
- ID情報
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- DOI : 10.3390/mi11020174
- ISSN : 2072-666X
- eISSN : 2072-666X