Kosei Takeuchi

Creating Alternative Afferent Input to Facilitate the Regeneration of Injured Primary Afferent Neurons

Emi Sawada, Toru Yamamoto, Naotaka Kishimoto, Dai Ooishi, Hiroyuki Sasakura, Kosei Takeuchi, Kenji Seo

Cureus, Feb 7, 2025

Endogenous chondroitin extends the lifespan and healthspan in C. elegans.

Yukimasa Shibata, Yuri Tanaka, Hiroyuki Sasakura, Yuki Morioka, Toshihiro Sassa, Shion Fujii, Kaito Mitsuzumi, Masashi Ikeno, Yukihiko Kubota, Kenji Kimura …

Scientific reports, 14(1) 4813-4813, Feb 27, 2024

Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury.

Yusuke Saijo, Narihito Nagoshi, Momotaro Kawai, Takahiro Kitagawa, Yu Suematsu, Masahiro Ozaki, Munehisa Shinozaki, Jun Kohyama, Shinsuke Shibata, Kosei Takeuchi …

Stem cell reports, Feb 6, 2024

Inhibitory effects of estetrol on the invasion and migration of immortalized human endometrial stromal cells

Akihiko Wakatsuki, Yinzhi Lin, Shiori Kojima, Hiroshi Matsushita, Kosei Takeuchi, Kazuo Umezawa

Endocrine Journal, 2024

Protocol for highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence in rodents.

Natsuki Matsushita, Shigeki Kato, Kayo Nishizawa, Masateru Sugawara, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi

STAR protocols, 4(4) 102667-102667, Oct 30, 2023

Inhibition of MLCK‑mediated migration and invasion in human endometriosis stromal cells by NF‑κB inhibitor DHMEQ.

Yinzhi Lin, Shiori Kojima, Ayaka Ishikawa, Hiroshi Matsushita, Yuka Takeuchi, Yuki Mori, Jun Ma, Kosei Takeuchi, Kazuo Umezawa, Akihiko Wakatsuki

Molecular medicine reports, 28(2), Aug, 2023

Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model.

Shunnosuke Kunoki, Hideki Tatsukawa, Yukinao Sakai, Hiroshi Kinashi, Tetsuyoshi Kariya, Yasuhiro Suzuki, Masashi Mizuno, Makoto Yamaguchi, Hiroyuki Sasakura, Masashi Ikeno …

Laboratory investigation; a journal of technical methods and pathology, 103(4) 100050-100050, Apr, 2023

Increased urinary albumin leakage is related to injuries of glomerular glycocalyx and podocytes, and associated with tubular dysfunction in preeclampsia.

Kazushi Watanabe, Tomohito Okamoto, Takuya Saitou, Ai Iwasaki, Hiroshi Matsushita, Kosei Takeuchi, Akimasa Asai, Yasuhiko Ito, Masanori Hara, Akihiko Wakatsuki

Pregnancy hypertension, 32 1-6, Feb 17, 2023

Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence

Natsuki Matsushita, Shigeki Kato, Kayo Nishizawa, Masateru Sugawara, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi

Cell Reports Methods, 3(2) 100393-100393, Feb, 2023

Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology

Natsuki Matsushita, Kayo Nishizawa, Shigeki Kato, Yoshio Iguchi, Ryoji Fukabori, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi

Journal of Neuroscience Methods, 381 109707-109707, Nov, 2022

Role of chondroitin sulfate in the developmental and healing process of the dental pulp in mice.

Hiroko Ida-Yonemochi, Kosei Takeuchi, Hayato Ohshima

Cell and tissue research, 388(1) 133-148, Apr, 2022 Peer-reviewed

ニューロサイエンスの最新情報途切れた神経回路を再びつなぐ人工シナプスコネクター

鈴木邦道, 武内恒成, 柚崎通介

Clinical Neuroscience, 40(2) 260-262, Feb, 2022

Bone marrow derived mast cells injected into the osteoarthritic knee joints of mice induced by sodium monoiodoacetate enhanced spontaneous pain through activation of PAR2 and action of extracellular ATP.

Hiroko Habuchi, Masashi Izumi, Junpei Dan, Takahiro Ushida, Masahiko Ikeuchi, Kosei Takeuchi

PloS one, 16(6) e0252590, 2021 Peer-reviewedLast author

A synthetic synaptic organizer protein restores glutamatergic neuronal circuits.

Kunimichi Suzuki, Jonathan Elegheert, Inseon Song, Hiroyuki Sasakura, Oleg Senkov, Keiko Matsuda, Wataru Kakegawa, Amber J Clayton, Veronica T Chang, Maura Ferrer-Ferrer …

Science (New York, N.Y.), 369(6507), Aug 28, 2020 Peer-reviewed

Chondroitin sulfate N-acetylgalactosyltransferase-1 knockout shows milder phenotype in experimental autoimmune encephalomyelitis than in wild type.

Rino Inada, Katsuichi Miyamoto, Noriko Tanaka, Kota Moriguchi, Kenji Kadomatsu, Kosei Takeuchi, Susumu Kusunoki

Glycobiology, 31(3) 260-265, Jul 28, 2020 Peer-reviewed

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.

Keiko Nakanishi, Hiroyuki Niida, Hidenori Tabata, Tsuyoshi Ito, Yuki Hori, Madoka Hattori, Yoshikazu Johmura, Chisato Yamada, Takashi Ueda, Kosei Takeuchi …

Cerebral cortex (New York, N.Y. : 1991), 29(9) 3738-3751, Aug 14, 2019 Peer-reviewed

Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1.

Hiroko Ida-Yonemochi, Wataru Morita, Nobuo Sugiura, Ryosuke Kawakami, Yuki Morioka, Yuka Takeuchi, Toshiya Sato, Shunichi Shibata, Hideto Watanabe, Takeshi Imamura …

Scientific reports, 8(1) 17134-17134, Nov 20, 2018 Peer-reviewed

Roles of CSGalNAcT1, a key enzyme in regulation of CS synthesis, in neuronal regeneration and plasticity.

Michihiro Igarashi, Kosei Takeuchi, Sayaka Sugiyama

Neurochemistry international, 119 77-83, Oct, 2018 Peer-reviewed

Increased Synthesis of Chondroitin Sulfate Proteoglycan Promotes Adult Hippocampal Neurogenesis in Response to Enriched Environment.

Jun Yamada, Satomi Nadanaka, Hiroshi Kitagawa, Kosei Takeuchi, Shozo Jinno

The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(39) 8496-8513, Sep 26, 2018 Peer-reviewed

Growth Cone Phosphoproteomics Reveals that GAP-43 Phosphorylated by JNK Is a Marker of Axon Growth and Regeneration.

Asami Kawasaki, Masayasu Okada, Atsushi Tamada, Shujiro Okuda, Motohiro Nozumi, Yasuyuki Ito, Daiki Kobayashi, Tokiwa Yamasaki, Ryo Yokoyama, Takeshi Shibata …

iScience, 4 190-203, Jun 29, 2018 Peer-reviewed

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