Papers

Peer-reviewed
Dec 1, 2016

Drug-administering persons’ exposure to oral anticancer drugs to be administered through a tube

Asian Journal of Pharmaceutical and Clinical Research
  • Masahiro Murakami
  • ,
  • Satoko Katsuragi
  • ,
  • Masako Ohno
  • ,
  • Makoto Shigematsu
  • ,
  • Ayumi Kishi
  • ,
  • Yoshito Zamami
  • ,
  • Fusao Komada
  • ,
  • Naomi Kurata
  • ,
  • Manabu Amano

Volume
9
Number
No.3
First page
316
Last page
319
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.22159/ajpcr.2016.v9s3.13040
Publisher
Innovare Academics Sciences Pvt. Ltd

Objective: The objective of this study was to quantitatively evaluate anticancer drug exposure of non-health care professionals who administer drugs through a tube employing a method devised by us. Methods: The subjects were 30 general volunteers aged 22-84 years. They wore gloves and administered Indian ink, simulating an anticancer drug, to a multipurpose adult human-type patient care simulator through a tube using 5 types of syringe, and the area stained with Indian ink was measured. Results: When comparing the number of pixels among the syringes regardless of age, Syringe B showed the lowest number (11.8±3.1 cm2), and there was a significant difference between Syringes B and E. Furthermore, we compared the total number of pixels in each age group regardless of the type of syringe. In the 20-year-old group, it was the lowest (10.9±2.3 cm2) showing significant differences in comparison with the other groups. When Syringe B was used, the number of pixels was markedly lower than on adopting the other syringes. Conclusion: It was clarified that the level of exposure to anticancer drugs markedly varies depending on the type of syringe and age. It was also clarified that the method to evaluate exposure to anticancer drugs using Indian ink devised by us is simple and useful.

Link information
DOI
https://doi.org/10.22159/ajpcr.2016.v9s3.13040
ID information
  • DOI : 10.22159/ajpcr.2016.v9s3.13040
  • ISSN : 2455-3891
  • ISSN : 0974-2441
  • SCOPUS ID : 85007524344

Export
BibTeX RIS