李承埈 (LEE SEUNG JUN) - マイポータル

基本情報

所属: (株)ダンディ·バイオサイエンス硏究所責任研究員

researchmap会員ID: B000309439

敗血症と抗生剤に付いて研究しています。

研究キーワード

研究分野

経歴

2020年5月 - 現在

HLBサイエンス(株), 戦略企画本部, 首席研究員
2018年6月 - 2020年3月

順天堂大学, 感染制御科学研究センター, ポスドク

学歴

2013年3月 - 2017年8月

建國大學校大学院, 医学科, 感染・免疫専攻
2007年3月 - 2013年2月

東國大学校, 科学技術大学, 生命工学科

受賞

2015年4月

Young Investigator Award, 韓国樹状細胞研究会

李承埈

論文

Drug repositioning of TANK-binding kinase 1 inhibitor CYT387 as an alternative for the treatment of Gram-negative bacterial sepsis.

Lee SJ, Gharbi A, You JS, Han HD, Kang TH, Hong SH, Park WS, Jung ID, Park YM

International Immunopharmacology 73 482-490 2019年6月査読有り
Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation.

Kim J, Durai P, Jeon D, Jung ID, Lee SJ, Park YM, Kim Y

Nutrients 10(7) 2018年7月査読有り
Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.

Park HJ, Lee SJ, Cho J, Gharbi A, Han HD, Kang TH, Kim Y, Lee Y, Park WS, Jung ID …

Journal of natural products 81(6) 1435-1443 2018年6月査読有り
Neoagarohexaose-mediated activation of dendritic cells via Toll-like receptor 4 leads to stimulation of natural killer cells and enhancement of antitumor immunity

Moon Hee Lee, Jong-Hwa Jang, Gun Young Yoon, Seung Jun Lee, Min-Goo Lee, Tae Heung Kang, Hee Dong Han, Hyuk Soon Kim, Wahn Soo Choi, Won Sun Park …

BMB REPORTS 50(5) 263-268 2017年5月査読有り
Neoagarooligosaccharides prevent septic shock by modulating A20-and cyclooxygenase-2-mediated interleukin-10 secretion in a septic-shock mouse model

Da Rae Kang, Gun Young Yoon, Joon Cho, Seung Jun Lee, Su Jin Lee, Hee Jo Park, Tae Heung Kang, Hee Dong Han, Won Sun Park, Young Kyung Yoon …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 486(4) 998-1004 2017年5月査読有り
Mycobacterium abscessus D-alanyl-D-alanine dipeptidase induces the maturation of dendritic cells and promotes Th1-biased immunity

Seung Jun Lee, Jong-Hwa Jang, Gun Young Yoon, Da Rae Kang, Hee Jo Park, Sung Jae Shin, Hee Dong Han, Tae Heung Kang, Won Sun Park, Young Kyung Yoon …

BMB REPORTS 49(10) 554-559 2016年10月査読有り
Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin

Hum Nath Jnawali, Dasom Jeon, Min-Cheol Jeong, Eunjung Lee, Bongwhan Jin, Sungweon Ryoo, Jungheon Yoo, In Duk Jung, Seung Jun Lee, Yeong-Min Park …

JOURNAL OF NATURAL PRODUCTS 79(4) 961-969 2016年4月査読有り
Mycobacterium abscessus MAB2560 induces maturation of dendritic cells via Toll-like receptor 4 and drives Th1 immune response

Su Jung Lee, Sung Jae Shin, Seung Jun Lee, Moon Hee Lee, Tae Heung Kang, Kyung Tae Noh, Yong Kyoo Shin, Han Wool Kim, Cheol-Heui Yun, In Duk Jung …

BMB REPORTS 47(9) 512-517 2014年9月査読有り
A Potential Protein Adjuvant Derived from Mycobacterium tuberculosis Rv0652 Enhances Dendritic Cells-Based Tumor Immunotherapy

Seung Jun Lee, Sung Jae Shin, Moon Hee Lee, Min-Goo Lee, Tae Heung Kang, Won Sun Park, Byoung Yul Soh, Jung Hee Park, Yong Kyoo Shin, Han Wool Kim …

PLOS ONE 9(8) e104351 2014年8月査読有り
Enhancement of Tumor-Specific T Cell-Mediated Immunity in Dendritic Cell-Based Vaccines by Mycobacterium tuberculosis Heat Shock Protein X

In Duk Jung, Sung Jae Shin, Min-Goo Lee, Tae Heung Kang, Hee Dong Han, Seung Jun Lee, Woo Sik Kim, Hong Min Kim, Won Sun Park, Han Wool Kim …

JOURNAL OF IMMUNOLOGY 193(3) 1233-1245 2014年8月査読有り

MISC

Tamarixetin exerts anti-inflammatory activity and prevents bacterial sepsis by increasing IL-10 production

Su Jin Lee, Seung Jun Lee, Yeong-Min Park, In Duk Jung

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 50 S276-S276 2017年11月

産業財産権

特開20190060■■■ (アメリカ) COMPOSITIONS FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Shin SJ, Park JH, Lee SJ, Kang TH, Soh BY
特許06475■■■ ■■■たんぱく質を有効成分として含むカルバペネム耐性グラム陰性菌に対する抗菌用の組成物

パクヨンミン, チョンイントゥク, イ, スンチュン
特開2668■■■ (ロシア) ANTIBACTERIAL COMPOSITION CONTAINING ■■■ PROTEIN AS AN ACTIVE INGREDIENT FOR CONTROLLING CARBAPENEM-RESISTANT GRAM NEGATIVE BACTERIA

Park YM, Jung ID, Lee SJ
特開107835■■■ (中国) Antibacterial composition for combating carbapenem-resistant gram-negative bacteria comprising ■■■ protein as active ingredient

朴荣敏, 郑寅德, 李承峻
特開20180078■■■ (アメリカ) ANTIBACTERIAL COMPOSITION FOR COMBATING CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Lee SJ
特開03292■■■ (ヨーロッパ) ANTIBACTERIAL COMPOSITION FOR COMBATING CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Lee SJ
特許10-1785■■■ (韓国) Composition comprising ■■■ and antibiotics for preventing or treating sepsis or septic shock

Park YM, Jung ID, Shin SJ, Lee SJ, Lee MG
特許10-1739305 (韓国) Composition for inducing maturation of antigen-presenting cell comprising relaxin

Park YM, Jung ID, Lee SJ
特許06062■■■ ■■■タンパク質を有効成分として含む敗血症または敗血症性ショックの予防または治療用薬学的組成物

パクヨンミン, ジョンインドゥク, シンスンジェ, パクジョンヒ, イ, スンジュン, カンテフン, ソ, ビョンヨル
特開10-2016-0118■■■ (韓国) Anti-bacterial composition comprising ■■■ against carbapenem-resistance gram-negative bacteria

Park YM, Jung ID, Lee SJ, Lee MG, Yoon YK
特開2016159■■■ (PCT) ANTIBACTERIAL COMPOSITION FOR COMBATING CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Lee SJ, Lee MG, Yoon YK
特開20160263■■■ (アメリカ) COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Shin SJ, Park JH, Lee SJ, Kang TH, Soh BY
特開02982■■■ (ヨーロッパ) COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK, COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Shin SJ, Park JH, Lee SJ, Kang TH, Soh BY
特開2015163■■■ (PCT) COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK, COMPRISING ■■■ PROTEIN AS ACTIVE INGREDIENT

Park YM, Jung ID, Shin SJ, Park JH, Lee SJ, Kang TH, Soh BY
特許10-1539■■■ (韓国) Anti-bacterial composition comprising ■■■

Park YM, Jung ID, Shin SJ, Park JH, Lim YT, Lee SJ, Kang TH, Ahn YS, Soh BY, Yun CH
特許10-1477■■■ (韓国) Composition comprising ■■■ for preventing or treating sepsis or septic shock

Park YM, Jung ID, Shin SJ, Park JH, Lee SJ, Kang TH, Soh BY