論文

2021年

Sequential Evaluation of Swallowing Function During Chemoradiotherapy for Head and Neck Cancer

Yonago Acta Medica
  • Satoshi Koyama
  • ,
  • Tsuyoshi Morisaki
  • ,
  • Kenkichiro Taira
  • ,
  • Takahiro Fukuhara
  • ,
  • Kazunori Fujiwara

64
3
開始ページ
234
終了ページ
239
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.33160/yam.2021.08.001
出版者・発行元
Tottori University Faculty of Medicine

Background: Many studies have addressed chronic dysphagia resulting from chemoradiotherapy for head and neck cancer (HNC) because of its severity, but changes in the swallowing function during chemoradiotherapy has been rarely reported. This study aimed to elucidate the changes in the swallowing function during chemoradiotherapy for HNC. Methods: From April 2018 to July 2020, 20 patients who underwent definitive or postoperative chemoradiotherapy at our hospital for head and neck squamous cell carcinoma were evaluated by flexible endoscopy with the Hyodo scoring system for swallowing, the Penetration-Aspiration Scale (PAS), and the Functional Outcomes Swallowing Scale (FOSS). Results: Assessments at the start of treatment, at 40 Gy, and at the end of treatment yielded these mean values: Hyodo score-0.39, 1.22, and 2.56; PAS-1.00, 1.05, and 1.5; FOSS-0.2, 0.55, and 1.1, respectively. The Dunn multiple comparison test was used for analysis to determine significance (P < 0.05). The Hyodo score and FOSS were significantly increased at the end of treatment versus initial evaluation; however, score was maintained at a tolerable level for oral intake. PAS did not show a significant increase. Conclusion: In conclusion, changes in the swallowing function during chemoradiotherapy for HNC were mild, and swallowing function was maintained at a tolerable level for oral intake.

リンク情報
DOI
https://doi.org/10.33160/yam.2021.08.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34429700
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380551
URL
https://www.jstage.jst.go.jp/article/yam/advpub/0/advpub_2021.08.001/_pdf
ID情報
  • DOI : 10.33160/yam.2021.08.001
  • eISSN : 1346-8049
  • PubMed ID : 34429700
  • PubMed Central 記事ID : PMC8380551

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