Satoshi Nagaie

Profile Information

Affiliation: Tohoku Medical Megabank Organization, Department of Health Record Informatics, Tohoku University

Degree: 博士（医学）(Mar, 2016, 東京医科歯科大学)

Researcher number: 00726466
ORCID ID: https://orcid.org/0000-0002-8152-4556
J-GLOBAL ID: 201901018119980978
researchmap Member ID: B000374963

External link: http://www.igm.megabank.tohoku.ac.jp/

Research Interests

Research Areas

Research History

Apr, 2023 - Present

Associate Professor, Department of Health Record Informatics, Tohoku University, Tohoku Medical Megabank Organization
Apr, 2022 - Mar, 2023

Senior Assistant Professor, Department of Health Record Informatics, Tohoku University, Tohoku Medical Megabank Organization
Apr, 2020 - Mar, 2022

Senior Assistant Professor, Tohoku Medical Megabank Organization, Department of Health Record Informatics, Tohoku University
Apr, 2018 - Mar, 2020

Tohoku Medical Megabank Organization, Department of Health Record Informatics, Tohoku University
Apr, 2016 - Mar, 2018

Tohoku Medical Megabank Organization, Department of Health Record Informatics, Tohoku University
Oct, 2012 - Mar, 2016

Tohoku Medical Megabank Organization, Department of Health Record Informatics, Tohoku University
Dec, 2009 - Mar, 2010

Graduate School of Biomedical Science, Tokyo Medical and Dental University
Sep, 2008 - Mar, 2009

Graduate School of Biomedical Science, Tokyo Medical and Dental University
Jun, 2008 - Mar, 2009

テクニカルスタッフ, 生命情報工学研究センター, 産業技術総合研究所
Apr, 2007 - Mar, 2008

Tokyo Medical and Dental University

Education

Apr, 2007 - Mar, 2011

Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
Apr, 2005 - Mar, 2007

Biomedical Science PhD Program, Tokyo Medical and Dental University
Apr, 2000 - Mar, 2005

Department of Applied Physics and Chemistry, Faculty of Electro-Communications, The University of Electro-Communications
Mar, 2003 - Feb, 2004

中国・ハルビン工程大学

Committee Memberships

Apr, 2018 - Present

東北大学東北メディカル・メガバンク機構倫理委員会
Sep, 2021 - Oct, 2022

CBI 学会 2022 年大会実行委員

Papers

Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study.

Kumi Nakaya, Naoki Nakaya, Mana Kogure, Rieko Hatanaka, Ippei Chiba, Ikumi Kanno, Satoshi Nagaie, Tomohiro Nakamura, Motoyori Kanazawa, Soichi Ogishima …

Journal of neurogastroenterology and motility, 30(2) 208-219, Apr 30, 2024
Development of phenotyping algorithms for hypertensive disorders of pregnancy (HDP) and their application in more than 22,000 pregnant women.

Satoshi Mizuno, Maiko Wagata, Satoshi Nagaie, Mami Ishikuro, Taku Obara, Gen Tamiya, Shinichi Kuriyama, Hiroshi Tanaka, Nobuo Yaegashi, Masayuki Yamamoto …

Scientific reports, 14(1) 6292-6292, Mar 15, 2024
The association between depressive symptoms and masked hypertension in participants with normotension measured at research center.

Sayuri Tokioka, Naoki Nakaya, Kumi Nakaya, Mana Kogure, Rieko Hatanaka, Ippei Chiba, Ikumi Kanno, Kotaro Nochioka, Hirohito Metoki, Takahisa Murakami …

Hypertension research : official journal of the Japanese Society of Hypertension, Oct 31, 2023
Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study.

Masato Takase, Naoki Nakaya, Tomohiro Nakamura, Mana Kogure, Rieko Hatanaka, Kumi Nakaya, Ippei Chiba, Ikumi Kanno, Kotaro Nochioka, Naho Tsuchiya …

Journal of atherosclerosis and thrombosis, Oct 6, 2023
Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study.

Satoshi Mizuno, Satoshi Nagaie, Gen Tamiya, Shinichi Kuriyama, Taku Obara, Mami Ishikuro, Hiroshi Tanaka, Kengo Kinoshita, Junichi Sugawara, Masayuki Yamamoto …

BMC pregnancy and childbirth, 23(1) 628-628, Aug 31, 2023
A knowledge representation model for family relationship to three generation

Kazuro Shimokawa, Mami Ishikuro, Taku Obara, Hirohito Metoki, Satoshi Mizuno, Satoshi Nagaie, Masato Nagai, Chizuru Yamanaka, Hiroko Matsubara, Mayumi Kato …

Bioinformation, 18(12) 1166-1172, Dec 31, 2022 Peer-reviewed
Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents.

Hisashi Shiga, Takahiro Takahashi, Manabu Shiraki, Yasuhiro Kojima, Tsuyotoshi Tsuji, Sho Takagi, Keiichiro Hiramoto, Naonobu Yokoyama, Mikako Sugimura, Masahiro Iwabuchi …

Scandinavian journal of gastroenterology, 58(4) 1-8, Oct 12, 2022 Peer-reviewed
過敏性腸症候群の有病に関連する要因の検討 TMM計画地域住民コホート調査

中谷久美, 中谷直樹, 永家聖, 小暮真奈, 畑中里衣子, 千葉一平, 菅野郁美, 小原拓, 中村智洋, 金澤素 …

日本公衆衛生学会総会抄録集, 81回 201-201, Sep, 2022
dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project.

Soichi Ogishima, Satoshi Nagaie, Satoshi Mizuno, Ryosuke Ishiwata, Keita Iida, Kazuro Shimokawa, Takako Takai-Igarashi, Naoki Nakamura, Sachiko Nagase, Tomohiro Nakamura …

Human genome variation, 8(1) 44-44, Dec 10, 2021 Peer-reviewed
The Data Use Ontology to streamline responsible access to human biomedical datasets.

Jonathan Lawson, Moran N Cabili, Giselle Kerry, Tiffany Boughtwood, Adrian Thorogood, Pinar Alper, Sarion R Bowers, Rebecca R Boyles, Anthony J Brookes, Matthew Brush …

Cell genomics, 1(2) None, Nov 10, 2021 Peer-reviewed
Management of family relationship information for a three-generation cohort study

Shimokawa K, Ishikuro M, Obara T, Metoki H, Mizuno S, Nagaie S, Nagai M, Yamanaka C, Matsubara H, Kato M …

bioRxiv, Jan, 2019
Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design

Takako Takai-Igarashi, Kengo Kinoshita, Masao Nagasaki, Soichi Ogishima, Naoki Nakamura, Sachiko Nagase, Satoshi Nagaie, Tomo Saito, Fuji Nagami, Naoko Minegishi …

BMC MEDICAL INFORMATICS AND DECISION MAKING, 17(1) 100, Jul, 2017 Peer-reviewed
A method to associate all possible combinations of genetic and environmental factors using GxE landscape plot.

Nagaie S, Ogishima S, Nakaya J, Tanaka H

Bioinformation, 11(3) 161-164, 2015 Peer-reviewed
Integrated Database and Knowledge Base for Genomic Prospective Cohort Study in Tohoku Medical Megabank Toward Personalized Prevention and Medicine

Soichi Ogishima, Takako Takai, Kazuro Shimokawa, Satoshi Nagaie, Hiroshi Tanaka, Jun Nakaya

Studies in Health Technology and Informatics, 216 1057, 2015 Peer-reviewed
CELLPEDIA: a repository for human cell information for cell studies and differentiation analyses

Akiko Hatano, Hirokazu Chiba, Harry Amri Moesa, Takeaki Taniguchi, Satoshi Nagaie, Koji Yamanegi, Takako Takai-Igarashi, Hiroshi Tanaka, Wataru Fujibuchi

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2011 bar046, 2011 Peer-reviewed
Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection

Mina Nakagawa, Naoya Sakamoto, Mayumi Ueyama, Kaoru Mogushi, Satoshi Nagaie, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Hiroshi Tanaka, Nobuyuki Enomoto …

JOURNAL OF GASTROENTEROLOGY, 45(6) 656-665, Jun, 2010 Peer-reviewed
Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells

Yuki Nishimura-Sakurai, Naoya Sakamoto, Kaoru Mogushi, Satoshi Nagaie, Mina Nakagawa, Yasuhiro Itsui, Megumi Tasaka-Fujita, Yuko Onuki-Karakama, Goki Suda, Kako Mishima …

JOURNAL OF GASTROENTEROLOGY, 45(5) 523-536, May, 2010 Peer-reviewed

Misc.

バイオバンク・ネットワーク~ブース出展におけるバイオバンク利活用促進について

長神風二, 井上真季子, 笠原直子, 永家聖, 信國宇洋, 大根田絹子, 荻島創一

日本遺伝子診療学会大会プログラム・抄録集, 30th, 2023
Development of the Japanese Version of Pre-eclampsia Ontology

水野聖士, 和形麻衣子, 永家聖, 八重樫伸生, 菅原準一, 菅原準一, 荻島創一

医療情報学, 40(3), 2020
東日本大震災による家屋損壊程度と過敏性腸症候群の関連

永家聖, 中谷直樹, 田中由佳里, 金澤素, 荻島創一, 高井貴子, 中村智洋, 土屋菜歩, 平田匠, 成田暁 …

日本疫学会学術総会講演集(Web), 29th 149 (WEB ONLY), 2019
妊娠高血圧症候群(HDP)フェノタイピングのためのアルゴリズムの検討

水野聖士, 永家聖, 飯田渓太, 笠原直子, 田宮元, 栗山進一, 八重樫伸生, 田中博, 菅原準一, 荻島創一

日本疫学会学術総会講演集(Web), 28th 133 (WEB ONLY), 2018
妊娠高血圧症候群(HDP)患者の病態分類のためのフェノタイピングアルゴリズムの開発

水野聖士, 和形麻衣子, 永家聖, 田宮元, 栗山進一, 八重樫伸生, 菅原準一, 荻島創一

日本妊娠高血圧学会雑誌, 25 94-94, 2018
三世代コホート調査における調査票結果回付における情報管理について

永家聖, 永家聖, 下川和郎, 佐藤ゆき, 石黒真美, 水野聖士, 宮下真子, 山中千鶴, 目時弘仁, 荻島創一 …

日本疫学会学術総会講演集(Web), 27th 116 (WEB ONLY), 2017
東北メディカル・メガバンクにおける過敏性腸症候群の有病割合:地域住民コホート調査

永家聖, 中谷直樹, 田中由佳里, 金澤素, 金澤素, 荻島創一, 高井貴子, 中村智洋, 土屋菜歩, 成田暁 …

日本公衆衛生学会総会抄録集, 76th 395-395, 2017
CELLPEDIA: Comprehensive human cell database toward cell differentiation analysis

Akiko Hatano, Harry AmriMoesa, Hirokazu Chiba, Takeaki Taniguchi, Satoshi Nagaie, Koji Yamanegi, Wataru Fujibuchi

IPSJ SIG technical reports, 2010(12) 1-4, Feb 25, 2010
CELLPEDIA: Comprehensive human cell database toward cell differentiation analysis

幡野晶子, 幡野晶子, MOESA Harry Amri, MOESA Harry Amri, 千葉啓和, 谷口丈晃, 永家聖, 永家聖, 山根木康嗣, 藤渕航

情報処理学会研究報告(CD-ROM), 2009(6), 2010
Study on the bioluminescent mechanism of luminous snail Latia neritoides: the Km value of luciferase and the product analyses of bioluminescent reactions of the Latia luciferin analogs

正木美津希, 間蓑雅, 永家聖, 中村光裕, 小島哲, 近江谷克裕, 牧昌次郎, 平野誉, 丹羽治樹

日本化学会講演予稿集, 85th(2) 862, 2005

Books and Other Publications

ヒト生体試料・データ取扱い実践ハンドブック : 適切なサンプル・データ取得からバイオバンク利活用、法規制まで、必須知識と標準フローをこの1冊に凝縮

日本生物資源産業利用協議会, 荻島, 創一, 森崎, 隆幸, 西原, 広史, 宮地, 勇人

羊土社, Aug, 2023 (ISBN: 9784758122658)
肝胆膵第86巻第2号

Feb 28, 2023
日本人の疾患と健康のためのバイオバンクとデータベース活用法 : 試料と情報の的確な探し方と使い方

後藤, 雄一, 村上, 善則, 高木, 利久, 荻島, 創一, 長神, 風二

羊土社, May, 2021 (ISBN: 9784758103947)
ヒト疾患のデータベースとバイオバンク : 情報をどう使い、どう活かすか?ゲノム医療をどう実現するか?/ 山本雅之, 荻島創一編集

山本雅之, 荻島創一

羊土社, 2017 (ISBN: 9784758103664)

Presentations

Five cluster groups found in the health state space of 96,093 population

Satoshi Nagaie, Satoshi Mizuno, Ryosuke Ishiwata, Soichi Ogishima

Oct 25, 2022
Minimum Common;Data Elements of Cancer-specific Clinical Information;Consent Information for;the Biobank Network in Japan

Nagaie S, Hirata M, Hattori K, Matsumura R, Kitajima K, Miyahara R, Noiri E, Imoto S, Kawano S, Morita M, Takagi T, Goto Y, Murakami Y, Ogishima S

ISBER 2020 Virtual Symposium, Oct 22, 2020
Minimum Common Data Elements of Biospecimen Quality Information for Biobank Network in Japan

Morita M, Hattori K, Matsumura R, Kitajima K, Miyahara R, Noiri E, Hirata M, Imoto S, Kawano S, Nagaie S, Takagi T, Goto Y, Murakami Y, Ogishima S

ISBER 2020 Virtual Symposium, Oct 22, 2020
Biobank network for promotion of utilization of biobank toward realization of genomic medicine in Japan

Ogishima S, Murakami Y, Goto Y, Morisaki T, Imoto S, Matsuda K, Hirata M, Yokota H, Suzuki K, Nagami F, Nagaie S, Miyamoto Y, Tomita T, Noiri H, Matsumura R, Miyahara R, Kitajima K, Kawano S, Morita M, Nishihara H, Nakae H, Yoshida M, Kohbata H, Muto M, Matsumoto S, Inazawa J, Tanaka T, Takemoto A, Nishiyama H, Takeuchi T, Takagi T

ISBER 2020 Virtual Symposium, Oct 22, 2020
GA4GH DURI Work Stream in GEM Japan 2020; localizing the Data Use Ontology and Machine-Readable Consent in the local research community

Chisato Yamasaki, Satoshi Nagaie, Minae Kawashima, Chihiro Hata, Shuichi Kawashima, Yuichi Kodama, Mizuki Morita, Natsuko Yamamoto, Akio Nagano, Keiko Katsui, Takako Takai, Soichi Ogishima

GA4GH 8th Plenary Meeting, Sep 29, 2020

Professional Memberships

Research Projects

機械学習によるフェノタイピングにもとづくポリジェニック・環境リスクスコアの開発

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2024

永家聖
ゲノム環境ワイド関連解析GE-WASによる遺伝子環境相互作用の同定

科学研究費助成事業若手研究(B), 若手研究(B), 日本学術振興会, Apr, 2017 - Mar, 2020

永家聖
Development of both the data exchange format of hierarchical omics data and the multi-axis and polyphenic ontology

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

NAKAYA Jun

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Misc.

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