Gen Sobue

Profile Information

Degree: (BLANK)

J-GLOBAL ID: 201101095817573328
researchmap Member ID: B000002950

External link

Research Interests

Research Areas

Research History

2002 - 2009

教授, 名古屋大学医学(系)研究科(研究院)
2007

教授, 名古屋大学医学系研究科・大学大学院
2007

教授, 名古屋大学医学系研究科・大学院
2004 - 2006

Graduate School of Medicine, Nagoya University
2002 - 2005

教授, 名古屋大学医学系研究科・大学院
2004

教授, 国立大学法人名古屋大学医学系研究科・大学院
1998 - 2001

School of Medicine, Nagoya University
2001

教授, 名古屋大学医学研究科・大学院
1995 - 1996

School of Medicine, Nagoya University
1994

School of Medicine, Aichi Medical University
1990 - 1992

School of Medicine, Aichi Medical University

Awards

2007

中日文化賞

祖父江元

Papers

181

Pupillary autonomic dysfunction in multiple system atrophy and Parkinson's disease: an assessment by eye-drop tests

Fumitada Yamashita, M. Hirayama, T. Nakamura, M. Takamori, N. Hori, K. Uchida, T. Hama, Gen Sobue

CLINICAL AUTONOMIC RESEARCH, 20(3) 191-197, Jun, 2010 Peer-reviewed
The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy

Keisuke Suzuki, Masahisa Katsuno, Haruhiko Banno, Yu Takeuchi, Motoshi Kawashima, Noriaki Suga, Atsushi Hashizume, Tetsuo Hama, Kei Uchida, Fumitada Yamashita …

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 81(5) 567-571, May, 2010 Peer-reviewed
Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody

Haruki Koike, Shigeru Koyano, Saori Morozumi, Yuichi Kawagashira, Masahiro Iijima, Masahisa Katsuno, Naoki Hattori, Steven Vernino, Gen Sobue

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 81(5) 586-587, May, 2010 Peer-reviewed
Suppression of melanin production by expression of HSP70.

Tatsuya Hoshino, Minoru Matsuda, Yasuhiro Yamashita, Masaya Takehara, Masayo Fukuya, Kazutaka Mineda, Daisuke Maji, Hironobu Ihn, Hiroaki Adachi, Gen Sobue …

The Journal of biological chemistry, 285(17) 13254-63, Apr 23, 2010 Peer-reviewed
Disrupted Transforming Growth Factor-beta Signaling in Spinal and Bulbar Muscular Atrophy

Masahisa Katsuno, Hiroaki Adachi, Makoto Minamiyama, Masahiro Waza, Hideki Doi, Naohide Kondo, Hiroyuki Mizoguchi, Atsumi Nitta, Kiyofumi Yamada, Haruhiko Banno …

JOURNAL OF NEUROSCIENCE, 30(16) 5702-5712, Apr, 2010 Peer-reviewed
Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.

Minoru Matsuda, Tatsuya Hoshino, Yasuhiro Yamashita, Ken-ichiro Tanaka, Daisuke Maji, Keizo Sato, Hiroaki Adachi, Gen Sobue, Hironobu Ihn, Yoko Funasaka …

The Journal of biological chemistry, 285(8) 5848-58, Feb 19, 2010 Peer-reviewed
Dorfin Ameliorates Phenotypes in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Jun Sone, Jun-ichi Niwa, Kaori Kawai, Shinsuke Ishigaki, Shin-ichi Yamada, Hiroaki Adachi, Masahisa Katsuno, Fumiaki Tanaka, Manabu Doyu, Gen Sobue

JOURNAL OF NEUROSCIENCE RESEARCH, 88(1) 123-135, Jan, 2010 Peer-reviewed
Familial Amyotrophic Lateral Sclerosis with a Novel G85S Mutation of Superoxide Dismutase 1 Gene: Clinical Features of Lower Motor Neuron Disease

Takanori Takazawa, Ken Ikeda, Takehisa Hirayama, Kiyokazu Kawabe, Yoshikazu Nakamura, Hirono Ito, Osamu Kano, Yasuhiro Yoshii, Fumiaki Tanaka, Gen Sobue …

INTERNAL MEDICINE, 49(2) 183-186, 2010 Peer-reviewed
[Lambert-Eaton myasthenic syndrome associated with pulmonary squamous cell carcinoma and circulating anti-P/Q-type voltage-gated calcium channel antibody].

Eiichi Katada, Tomohiko Nakamura, Hirohisa Watanabe, Noriyuki Matsukawa, Kosei Ojika, Gen Sobue

Rinsho shinkeigaku = Clinical neurology, 50(1) 17-9, Jan, 2010 Peer-reviewed
An autopsied case of panencephalopathic-type Creutzfeldt-Jakob disease with mutation in the prion protein gene at codon 232 and type 1 prion protein

Tetsuo Hama, Yasushi Iwasaki, Hisayoshi Niwa, Mari Yoshida, Yoshio Hashizume, Tetsuyuki Kitamoto, Nobuyuki Murakami, Gen Sobue

NEUROPATHOLOGY, 29(6) 727-734, Dec, 2009 Peer-reviewed
Distinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathy

Haruki Koike, Yukio Ando, Mitsuharu Ueda, Yuichi Kawagashira, Masahiro Iijima, Junko Fujitake, Michiyuki Hayashi, Masahiko Yamamoto, Eiichiro Mukai, Tomohiko Nakamura …

JOURNAL OF THE NEUROLOGICAL SCIENCES, 287(1-2) 178-184, Dec, 2009 Peer-reviewed
A case of Gerstmann-Straussler-Scheinker syndrome with the P105L prion protein gene mutation presenting with ataxia and extrapyramidal signs without spastic paraparesis

Yasushi Iwasaki, Mayuki Kizawa, Norio Hori, Tetsuyuki Kitamoto, Gen Sobue

CLINICAL NEUROLOGY AND NEUROSURGERY, 111(7) 606-609, Sep, 2009 Peer-reviewed
HSP70 Confers Protection against Indomethacin-Induced Lesions of the Small Intestine

Teita Asano, Ken-Ichiro Tanaka, Naoki Yamakawa, Hiroaki Adachi, Gen Sobue, Hidemi Goto, Koji Takeuchi, Tohru Mizushima

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 330(2) 458-467, Aug, 2009 Peer-reviewed
Pathogenesis-targeting therapeutics for spinal and bulbar muscular atrophy (SBMA)

Keisuke Suzuki, Masahisa Kastuno, Haruhiko Banno, Gen Sobue

NEUROPATHOLOGY, 29(4) 509-516, Aug, 2009 Peer-reviewed
TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases

Yohei Iguchi, Masahisa Katsuno, Jun-ichi Niwa, Shin-ichi Yamada, Jun Sone, Masahiro Waza, Hiroaki Adachi, Fumiaki Tanaka, Koh-ichi Nagata, Nariko Arimura …

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(33) 22059-22066, Aug, 2009 Peer-reviewed
Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy

Isabella Palazzolo, Conor Stack, Lingling Kong, Antonio Musaro, Hiroaki Adachi, Masahisa Katsuno, Gen Sobue, J. Paul Taylor, Charlotte J. Sumner, Kenneth H. Fischbeck …

NEURON, 63(3) 316-328, Aug, 2009 Peer-reviewed
Molecular-targeted therapy for motor neuron disease

Haruhiko Banno, Masahisa Katsuno, Keisuke Suzuki, Yohei Iguchi, Hiroaki Adachi, Fumiaki Tanaka, Gen Sobue

Brain and Nerve, 61(8) 891-900, Aug, 2009 Peer-reviewed
A Role for HSP70 in Protecting against Indomethacin-induced Gastric Lesions

Shintaro Suemasu, Ken-Ichiro Tanaka, Takushi Namba, Tomoaki Ishihara, Takashi Katsu, Mitsuaki Fujimoto, Hiroaki Adachi, Gen Sobue, Koji Takeuchi, Akira Nakai …

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(29) 19705-19715, Jul, 2009 Peer-reviewed
The significance of carpal tunnel syndrome in transthyretin Val30Met familial amyloid polyneuropathy.

Koike H, Morozumi S, Kawagashira Y, Iijima M, Yamamoto M, Hattori N, Tanaka F, Nakamura T, Hirayama M, Ando Y …

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 1-7, Jul 1, 2009 Peer-reviewed
Heterogeneity and continuum of multiple sclerosis phenotypes in Japanese according to the results of the fourth nationwide survey

Takaaki Ishizu, Jun-ichi Kira, Manabu Osoegawa, Toshiyuki Fukazawa, Seiji Kikuchi, Kazuo Fujihara, Makoto Matsui, Tatsuo Kohriyama, Gen Sobue, Takashi Yamamura …

JOURNAL OF THE NEUROLOGICAL SCIENCES, 280(1-2) 22-28, May, 2009 Peer-reviewed

Misc.

180

座長の言葉

三本博, 祖父江元

臨床神経学, 48(11), Nov 1, 2008
孤発性ALS病態関連分子の探索と疾患モデルの開発

田中章景, 和座雅浩, 丹羽淳一, 山本正彦, 祖父江元

臨床神経学, 48(11) 970-972, Nov 1, 2008
代謝・栄養性ニューロパチー

服部直樹, 小池春樹, 祖父江元

臨床神経学, 48(11) 1026-1027, Nov 1, 2008
モデル教育コア・カリキュラムおよび卒前教育における神経内科の現状に関するアンケート全国調査

佐々木秀直, 有村公良, 糸山泰人, 郭伸, 吉良潤一, 中島健二, 天野隆弘, 井上聖啓, 魚住武則, 幸原伸夫 …

臨床神経学, 48(8) 556-562, Aug 1, 2008
Pathological features of Guillain-Barre syndrome

226(2) 135-138, Jul 12, 2008
神経病学--血管系を除く (特集臨床医学の展望2008--診断および治療上の進歩(6))

祖父江元

日本医事新報, (4376) 57-63, Mar 8, 2008
Diagnosis and therapeutic procedures of peripheral neuropathy

57(2) 340-342, Feb, 2008
パーキンソン病における^<123>I-MIBG心筋シンチグラフィと起立負荷試験の関連性

土井英樹, 新美由紀, 長谷川康博, 三輪茂, 山名知子, 高城晋, 高橋昭, 祖父江元

臨床神経学 : CLINICAL NEUROLOGY, 48(1) 56-59, Jan 1, 2008
各種難病の最新治療情報孤発性ALSの遺伝子発現プロファイル作成から疾患モデル作成と治療への展開

田中章景, 山本正彦, 祖父江元

難病と在宅ケア, 13(8) 66-69, Nov, 2007
座長の言葉

清水輝夫, 祖父江元

臨床神経学 : CLINICAL NEUROLOGY, 47(11), Nov 1, 2007
イントロダクション

祖父江元

臨床神経学 : CLINICAL NEUROLOGY, 47(11), Nov 1, 2007
Animal models of neurodegenerative diseases on the road to disease-modifying therapy : Spinal and bulbar muscular atrophy

SOBUE Gen

Clinical neurology., 47(11) 941-943, Nov 1, 2007
ALS脊髄前角の遺伝子発現プロファイル (特集 ALS--研究と診療の進歩)

山本正彦, 田中章景, 祖父江元

Brain and nerve, 59(10) 1129-1139, Oct, 2007
慢性頭痛--持続性頭痛緊張型頭痛 (特集よく診る頭痛と危険な頭痛)

中村友彦, 祖父江元

臨牀と研究, 84(9) 1227-1230, Sep, 2007
1. Adverse Effects of Therapeutic Drugs on Peripheral Nervous System

Oki Yumiko, Koike Haruki, Sobue Gen

Nihon Naika Gakkai Kaishi, 96(8) 1591-1597, Aug 10, 2007
神経変性疾患の病態抑止療法 : ポリグルタミン病をモデルに

祖父江元

Drug delivery system, 22(3), May 10, 2007
神経病学--血管系を除く (特集臨床医学の展望2007--診断および治療上の進歩(7))

祖父江元

日本医事新報, (4325) 57-62, Mar 17, 2007
Integrated molecular medicine for neuronal and neoplastic disorders

TANAKA Fumiaki, SOBUE Gen

79(2) 121-130, Feb 25, 2007
Heat shock protein 27 遺伝子の変異をみとめた distal hereditary motor neuropathy type II

西林百佳, 国分則人, 中村新, 平田幸一, 山本正彦, 祖父江元

臨床神経学 : CLINICAL NEUROLOGY, 47(1) 50-52, Jan 1, 2007
Effective detection of cardiac sympathetic denervation using dobutamine infusion in patients with Parkinson disease : correlation with cardiac ^<123>I-metaiodobenzylguanidine (MIBG) uptake-a follow-up report

NAKAMURA Tomohiko, HIRAYAMA Masaaki, ITO Hiroki, TAKAMORI Motoko, HORI Norio, SOBUE Gen

43(5) 431-435, Oct 15, 2006

Books and Other Publications

Annual Review神経〈2010〉

中外医学社, Jan, 2010 (ISBN: 4498128680)
内科学書(全7冊) 改訂第7版

中山書店, Oct 26, 2009 (ISBN: 4521731732)
脳・神経系疾患

祖父江元

中山書店, Nov 30, 2005 (ISBN: 4521624812)
看護のための最新医学講座第1巻

中山書店, Feb, 2002 (ISBN: 4521632416)
神経・筋疾患の最新医療 (先端医療シリーズ (14神経・筋疾患))

杉田秀夫, 福内靖男, 柴崎浩, 糸山泰人, 小林祥泰, 祖父江元

先端医療技術研究所, Nov, 2001 (ISBN: 492508917X)