SORIMACHI Hiroyuki

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Name
SORIMACHI Hiroyuki
Affiliation
, Tokyo Metropolitan Institute of Medical Science
Section
Dept. of Advanced Science for Biomolecules, Calpain Project
Job title
Department Head, Project Leader
Degree
Ph.D.(The University of Tokyo), M.Sc.(The University of Tokyo)

Research Areas

 
 

Education

 
 
 - 
1988
Department of Biochemistry, Graduate School of Science, The University of Tokyo
 
 
 - 
1988
Graduate School, Division of Science, The University of Tokyo
 
 
 - 
1986
Faculty of Science, The University of Tokyo
 

Committee Memberships

 
 
   
 
ASBMB, American Society for Biochemistry and Molecular Biology  Regular member
 

Awards & Honors

 
1999
Young Investigator Award (The Japanese Biochemical Society)
 

Published Papers

 
Shinkai-Ouchi F, Koyama S, Ono Y, Hata S, Ojima K, Shindo M, DuVerle D, Ueno M, Kitamura F, Doi N, Takigawa I, Mamitsuka H, Sorimachi H.
Molecular and Cellular Proteomics   15(4) 1262-1280   2016   [Refereed]
Miyazaki T, Tonami K, Hata S, Aiuchi T, Ohnishi K, Lei X.-F, Kim-Kaneyama J.-R, Takeya M, Itabe H, Sorimachi H, Kurihara H, Miyazaki A.
Journal of Clinical Investigation   126(9) 3417-3432   2016   [Refereed]
Ono Y, Saido T.C, Sorimachi H.
Nature Reviews Drug Discovery   15(12) 854-876   2016   [Refereed]
Ono Y, Ojima K, Shinkai-Ouchi F, Hata S, Sorimachi H.
Biochimie   122 169-187   2016   [Refereed]
Yasuko Ono, Hiroyuki Sorimachi
Data in Brief   5 366   Dec 2015   [Refereed]
Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, Takahama Y, Murata S, Nature communications, vol. 6, pp. 7484
6 7484   2015   [Refereed]
Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, Takahama Y, Murata S, Nature communications, 2015, vol. 6, pp. 7484
Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, Takahama Y, Murata S.
Nature Communications   6    2015   [Refereed]
Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, Takasugi M, Yamakoshi K, Sorimachi H, Kanda H, Ishikawa Y, Sone S, Nishioka Y, Ohtani N, Hara E, Nature communications, vol. 6, pp. 7035
6 7035   2015   [Refereed]
Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, Takasugi M, Yamakoshi K, Sorimachi H, Kanda H, Ishikawa Y, Sone S, Nishioka Y, Ohtani N, Hara E, Nature communications, 2015, vol. 6, pp. 7035
Ono Y, Shindo M, Doi N, Kitamura F, Gregorio C.C, Sorimachi H.
Proceedings of the National Academy of Sciences of the United States of America   111(51) E5527-E5536   2014   [Refereed]
Buck D, Smith J.E, Chung C.S, Ono Y, Sorimachi H, Labeit S, Granzier H.L.
Journal of General Physiology   143(2) 215-230   2014   [Refereed]
Ojima K, Ono Y, Hata S, Noguchi S, Nishino I, Sorimachi H.
Genes to Cells   19(11) 830-841   2014   [Refereed]
Maemoto Y, Ono Y, Kiso S, Shibata H, Takahara T, Sorimachi H, Maki M.
FEBS Journal   281(16) 3642-3655   2014   [Refereed]
Ono Y, Iemura S.-I, Novak S.M, Doi N, Kitamura F, Natsume T, Gregorio C.C, Sorimachi H.
Journal of Molecular Biology   425(16) 2955-2972   2013   [Refereed]
Sorimachi H, Hata S, Ono Y.
Handbook of Proteolytic Enzymes   2 2027-2038   2013   [Refereed]
Sorimachi H, Hata S, Ono Y.
Handbook of Proteolytic Enzymes   2 2011-2017   2013   [Refereed]
Sorimachi H, Hata S, Ono Y.
Handbook of Proteolytic Enzymes   2 2018-2022   2013   [Refereed]
Hata S, Kitamura F, Sorimachi H.
Genes to Cells   18(9) 753-763   2013   [Refereed]
Anagli J, Wang K.K.W, Ono Y, Sorimachi H.
Proteases: Structure and Function   395-431   2013   [Refereed]
Tonami K, Hata S, Ojima K, Ono Y, Kurihara Y, Amano T, Sato T, Kawamura Y, Kurihara H, Sorimachi H.
PLoS Genet   9(8) e1003668   2013   [Refereed]
Sorimachi H, Hata S, Ono Y.
Handbook of Proteolytic Enzymes   2 2007-2011   2013   [Refereed]
Sorimachi H, Hata S, Ono Y.
Handbook of Proteolytic Enzymes   2 1995-2007   2013   [Refereed]
Sorimachi H, Mamitsuka H, Ono Y.
Biological Chemistry   393(9) 853-871   2012   [Refereed]
Sorimachi Hiroyuki, Ono Yasuko
Cardiovascular Research   96(1) 11-22   2012   [Refereed]
Ozaki T, Nakazawa M, Yamashita T, Sorimachi H, Hata S, Tomita H, Isago H, Baba A, Ishiguro S.-I.
Biochimica et Biophysica Acta - Molecular Basis of Disease   1822(11) 1783-1795   2012   [Refereed]
Harada E, Nakagawa J, Asano T, Taoka M, Sorimachi H, Ito Y, Aigaki T, Matsuo T.
PLoS ONE   7(1)    2012   [Refereed]
Hata S, Ueno M, Kitamura F, Sorimachi H.
Journal of Biochemistry   151(4) 417-422   2012   [Refereed]
Ono Y, Sorimachi H.
Biochimica et Biophysica Acta - Proteins and Proteomics   1824(1) 224-236   2012   [Refereed]
Hata S, Sorimachi H.
Nippon rinsho. Japanese journal of clinical medicine   69(6) 1116-1122   2011   [Refereed]
Ojima K, Ono Y, Ottenheijm C, Hata S, Suzuki H, Oe M, Nakajima I, Muroya S, Granzier H, Sorimachi H.
Molecular Biology of the Cell   22    2011   [Refereed]
Kondo H, Ezura Y, Nakamoto T, Hayata T, Notomi T, Sorimachi H, Takeda S, Noda M.
Journal of Cellular Biochemistry   112(12) 3525-3530   2011   [Refereed]
Sorimachi H, Hata S, Ono Y.
Journal of Biochemistry   150(1) 23-37   2011   [Refereed]
S{á}enz A, Ono Y, Sorimachi H, Goicoechea M, Leturcq F, Bl{á}zquez L, Garc{í}a-Bragado F, Marina A, Poza J.J, Azpitarte M, Doi N, Urtasun M, Kaplan J.-C, de Munain A.L.
Muscle and Nerve   44(5) 710-714   2011   [Refereed]
duVerle D.A, Ono Y, Sorimachi H, Mamitsuka H.
PLoS ONE   6(5)    2011   [Refereed]
Sorimachi H, Hata S, Ono Y.
Proceedings of the Japan Academy Series B: Physical and Biological Sciences   87(6) 287-327   2011   [Refereed]
Une contribution á l'histoire de la découverte des calpaïnopathies.
Fardeau, M., Beckmann, J.S., Sorimachi, H., and Urtizberea, J. A.
Les Cahiers de Myologie   2 5-10   2010
CaMPDB: a Resource for Calpain and Modulatory Proteolysis.
duVerle, D. A., Takigawa, I. Ono, Y., Sorimachi, H., and Mamitsuka, H.
Genome Informatics   22 202-214   2010
Ojima K, Ono Y, Doi N, Kitamura F, Hata S, Kawabata Y, Suzuki K, Maeda T, Abe K, Nakao H, Aiba A, Nakao K, Suzuki H, Kawahara H, Witt C, Labeit S, Ottenheijm C, Granzier H, Toyama-Sorimachi N, Sorimachi M, Sorimachi H.
Neuromuscular Disorders   20(9-10) 598-599   2010   [Refereed]
Ono Y, Ojima K, Toru F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H.
Neuromuscular Disorders   20(9-10) 608   2010   [Refereed]
Ojima Koichi, Kawabata Yukiko, Nakao Harumi, Nakao Kazuki, Doi Naoko, Kitamura Fujiko, Ono Yasuko, Hata Shoji, Suzuki Hidenori, Kawahara Hiroyuki, Bogomolovas Julius, Witt Christian, Ottenheijm Coen, Labeit Siegfried, Granzier Henk, Toyama-Sorimachi Noriko, Sorimachi Michiko, Suzuki Koichi, Maeda Tatsuya, Abe Keiko, Aiba Atsu, Sorimachi Hiroyuki
Journal of Clinical Investigation   120(8) 2672-2683   2010   [Refereed]
Yamada, M., Yoshida, Y., Mori, D., Takitoh, T., Kengaku, M., Umeshima, H., Takao, K., Miyakawa, T., Sato, M., Sorimachi, H., Wynshaw-Boris, A., and Hirotsune, S.
Nat. Med.   15(10) 1202-1207   2009
Koyama Suguru, Hata Shoji, Witt Christian C, Ono Yasuko, Lerche Stefanie, Ojima Koichi, Chiba Tomoki, Doi Naoko, Kitamura Fujiko, Tanaka Keiji, Abe Keiko, Witt Stephanie H, Rybin Vladimir, Gasch Alexander, Franz Thomas, Labeit Siegfried, Sorimachi Hiroyuki
Journal of Molecular Biology   376(5) 1224-1236   2008   [Refereed]
Hata S, Sorimachi H.
Seikagaku   79(1) 46-50   2007   [Refereed]
Ono Yasuko, Hayashi Chikako, Doi Naoko, Kitamura Fujiko, Shindo Mayumi, Kudo Kenichi, Tsubata Takuichi, Yanagida Mitsuaki, Sorimachi Hiroyuki
Biotechnology Journal   2(5) 565-576   2007   [Refereed]
Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H.
Journal of Biological Chemistry   281(27) 18519-18531   2006   [Refereed]
Nakajima K, Asakura T, Maruyama J, Morita Y, Oike H, Shimizu-Ibuka A, Misaka T, Sorimache H, Arai S, Kitamoto K, Abe K.
Applied and Environmental Microbiology   72(5) 3716-3723   2006   [Refereed]
Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H.
Febs Journal   273 50-51   2006   [Refereed]
Yajima Y, Sato M, Sorimachi H, Inomata M, Maki M, Kawashima S.
Endocrinology   147(10) 4811-4819   2006   [Refereed]
Ojimal Koichi, Ono Yasuko, Hat Shoji, Koyama Suguru, Doi Naoko, Sorimachi Hiroyuki
Cell Structure and Function   30 58   2005   [Refereed]
Hata Shoji, Koyama Suguru, Kawahara Hiroyuki, Doi Naoko, Abe Keiko, Suzuki Koichi, Sorimachi Hiroyuki
Cell Structure and Function   30 102   2005   [Refereed]
Kondo H, Sorimachi H, Takeda S, Noda M.
Journal of Bone and Mineral Research   20(9) S44   2005   [Refereed]
Koyama Suguru, Hata Shoji, Ono Yasuko, Ojima Koichi, Chiba Tomoki, Doi Naoko, Witt Christian, Abe Keiko, Labeit Siegfried, Sorimachi Hiroyuki
Cell Structure and Function   30 100   2005   [Refereed]
Hayashi M, Fukuzawa T, Sorimachi H, Maeda T.
Molecular and Cellular Biology   25(21) 9478-9490   2005   [Refereed]
Ono Yasuko, Ojima Koichi, Doi Naoko, Witt Christian, Witt Stephanie, Granzier Henk, Labeit Siegfried, Suzuki Koichi, Sorimachi Hiroyuki
Cell Structure and Function   30 102   2005   [Refereed]
Sorimachi Hiroyuki, Qjima Koichi, Katsui Yukiko, Hata Shoji, Koyama Suguru, Doi Naoko, Ono Yasuko
Cell Structure and Function   30 102   2005   [Refereed]
Ojima K, Kawabata Y, Ono Y, Hata S, Koyama S, Witt C, Labeit S, Sorimachi H.
Molecular Biology of the Cell   15 274A-275A   2004   [Refereed]
Kawabata Y, Hata S, Ono Y, Ito Y, Suzuki K, Abe K, Sorimachi H.
Febs Letters   557(1-3) 293   2004   [Refereed]
Sorimachi H, Hata S, Katsui Y, Ono Y, Torii F, Yoshioka K, Kimura E, Suzuki K, Abe K.
Journal of Pharmacological Sciences   91 14P   2003   [Refereed]
Sorimachi Hiro, Hata Shoji, Nakagawa Kazu, Kimura Eiichi, Katsui Yuki, Torii Fuku, Ono Yasuko, Suzuki Koichi, Abe Keiko
Neuroscience Research Supplement   (26) S8   2002   [Refereed]
Spencer M. J, Potts A, Richard I, Sorimachi H, Chamberlain J, Beckmann J.
Neuromuscular Disorders   11(6-7) 652   2001   [Refereed]
Hata S, Sorimachi H, Suzuki K.
Seikagaku   73(9) 1129-1140   2001   [Refereed]
Reverter D, Strobl S, Fernandez-Catalan C, Sorimachi H, Suzuki K, Bode W.
Biological Chemistry   382(5) 753-766   2001   [Refereed]
Sorimachi H.
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   46(11 Suppl) 1772-1780   2001   [Refereed]
McElhinny A. S, Kakinuma K, Geach A. J, Sorimachi H, Labeit S, Gregorio C. C.
Molecular Biology of the Cell   12 38A-39A   2001   [Refereed]
Hata S, Sorimachi H, Nakagawa K, Maeda T, Abe K, Suzuki K.
Febs Letters   501(2-3) 111-114   2001   [Refereed]
Bickerstaffe R, Ilian M, Sorimachi H.
Journal of Dairy Science   84(Supplement 1) 438   2001   [Refereed]
Bang M. L, Mudry R. E, McElhinny A. S, Sorimachi H, Trombitas K, Geach A. J, Granzier H, Labeit S, Gregorio C. C.
Molecular Biology of the Cell   11 74A   2000   [Refereed]
Sorimachi H.
Seikagaku   72(11) 1297-1315   2000   [Refereed]
Sorimachi H, Ono Y, Suzuki K.
Methods in molecular biology (Clifton, N.J.)   144 75-84   2000   [Refereed]
Koike H, Kouchi Z, Kinouchi T, Maeda T, Sorimachi H, Saido T. C, Maruyama K, Okuyama A, Suzuki K, Ishiura S.
Cytotechnology   33(1-3) 213-219   2000   [Refereed]
Kitagaki H, Tomioka S, Yoshizawa T, Sorimachi H, Saido T.C, Ishiura S, Suzuki K.
Bioscience, Biotechnology and Biochemistry   64(4) 689-695   2000   [Refereed]
Hata S, Sato T, Sorimachi H, Ishiura S, Suzuki K.
Journal of Virological Methods   84(2) 117-126   2000   [Refereed]
Koike H, Seki H, Kouchi Z, Ito M, Kinouchi T, Tomioka S, Sorimachi H, Saido T. C, Maruyama K, Suzuki K, Ishiura S.
Journal of Biochemistry   126(1) 235-242   1999   [Refereed]
Watanabe T, Sasagawa N, Usuki F, Koike H, Saitoh N, Sorimachi H, Maruyama K, Nakase H, Takagi A, Ishiura S, Suzuki K.
Journal of the Neurological Sciences   167(1) 26-33   1999   [Refereed]
Gregorio C. C, Granzier H, Sorimachi H, Labeit S.
Current Opinion in Cell Biology   11(1) 18-25   1999   [Refereed]
Futai E, Sorimachi H, Jeong S, Kitamoto K, Ishiura S, Suzuki K.
Journal of Bioscience and Bioengineering   88(4) 438-440   1999   [Refereed]
Kinbara K, Sorimachi H, Ishiura S, Suzuki K.
Biochemical Pharmacology   56(4) 415-420   1998   [Refereed]
Labeit S, Linke W. A, Freiburg A, Sorimachi H, Gregorio C. C, Granzier H, Kolmerer B.
Faseb Journal   12(4) A313   1998   [Refereed]
Sorimachi H, Suzuki K.
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   43(12 Suppl) 1666-1674   1998   [Refereed]
Suzuki K, Sorimachi H.
Febs Letters   433(1-2) 1-4   1998   [Refereed]
SORIMACHI H, SUZUKI K
Tanpakushitsu Kakusan Koso   42(14 Suppl) 2433-40   1997   [Refereed]
Freiburg A, Sorimachi H, Suzuki S, Stier G, Kolmerer B, Linke W, Labeit S.
European Journal of Cell Biology   72(SUPPL. 43) 60   1997   [Refereed]
Jeong S.-Y, Sorimachi H, Lee H.-J, Ishiura S, Suzuki K.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology   118(3) 539-547   1997   [Refereed]
Sorimachi H, Suzuki K.
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   42(14 Suppl) 2433-2440   1997   [Refereed]
Tagawa K, Sorimachi H, Ishiura S, Suzuki K, Tagawa K, Seyama Y.
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   42(14 Suppl) 2165-2174   1997   [Refereed]
Sorimachi H, Kimura S, Kinbara K, Kazama J, Takahashi M, Yajima H, Ishiura S, Sasagawa N, Nonaka I, Sugita H, Maruyama K, Suzuki K.
Advances in Biophysics   33 101-122   1996   [Refereed]
Sorimachi H, Amano S, Ishiura S, Suzuki K.
Biochimica et Biophysica Acta - Gene Structure and Expression   1309(1-2) 37-41   1996   [Refereed]
Yazaki M, Tagawa K, Maruyama K, Sorimachi H, Tsuchiya T, Ishiura S, Suzuki K.
Neuroscience Letters   221(1) 57-60   1996   [Refereed]
Saitoh N, Sasagawa N, Koike H, Shimokawa M, Sorimachi H, Ishiura S, Suzuki K.
Neuroscience Letters   218(3) 214-216   1996   [Refereed]
Sorimachi H, Tsukahara T, Okada-Ban M, Sugita H, Ishiura S, Suzuki K.
BBA - Gene Structure and Expression   1261(3) 381-393   1995   [Refereed]
Yoshizawa T, Sorimachi H, Tomioka S, Ishiura S, Suzuki K.
Febs Letters   358(1) 101-103   1995   [Refereed]
SORIMACHI H, SASAGAWA N, MARUYAMA K, ARAHATA K, ISHIURA S, SUZUKI K
Rinsho Shinkeigaku   34(12) 1230-2   1994   [Refereed]
Saido T.C, Sorimachi H, Suzuki K.
FASEB Journal   8(11) 814-822   1994   [Refereed]
Sorimachi H, Sasagawa N, Maruyama K, Arahata K, Ishiura S, Suzuki K.
Clinical Neurology   34(12) 1230-1232   1994   [Refereed]
Sorimachi Hiroyuki, Suzuki Koihci
Biological functions of proteases and inhibitors   35-46   1994   [Refereed]
Sorimachi H.
Seikagaku. The Journal of Japanese Biochemical Society   65(9) 1170-1174   1993   [Refereed]
Harigaya W, Saido T. C, Nagao S, Miyata Y, Saito Y, Sorimachi H, Tuchiya T, Suzuki K, Yahara I, Kawashima S.
Zoological Science (Tokyo)   10(SUPPL.) 14   1993   [Refereed]
Sorimachi H, Ishiura S, Suzuki K.
Journal of Biological Chemistry   268(26) 19476-19482   1993   [Refereed]

Research Grants & Projects

 
Study on physiological functions of tissue-specific calpain.
Physiological functions of connectin-titin
Protease Proteomics