2012年10月
Comparison of Long-Term Outcome After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Unprotected Left Main Coronary Artery Disease (from the CREDO-Kyoto PCI/CABG Registry Cohort-2)
AMERICAN JOURNAL OF CARDIOLOGY
- 巻
- 110
- 号
- 7
- 開始ページ
- 924
- 終了ページ
- 932
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.amjcard.2012.05.022
- 出版者・発行元
- EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
The long-term outcome of percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) for unprotected left main coronary artery disease (ULMCAD) remains to be investigated. We identified 1,005 patients with ULMCAD of 15,939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG Registry Cohort-2. Cumulative 3-year incidence of a composite of death/myocardial infarction (MI)/stroke was significantly higher in the PCI group than in the CABG group (22.7% vs 14.8%, p = 0.0006, log-rank test). However, the adjusted outcome was not different between the PCI and CABG groups (hazard ratio [FIR] 1.30, 95% confidence interval [CI] 0.79 to 2.15, p = 0.30). Stratified analysis using the SYNTAX score demonstrated that risk for a composite of death/MI/stroke was not different between the 2 treatment groups in patients with low (<23) and intermediate (23 to 33) SYNTAX scores (adjusted HR 1.70, 95% CI 0.77 to 3.76, p = 0.19; adjusted HR 0.86, 95% CI 0.37 to 1.99, p = 0.72, respectively), whereas in patients with a high SYNTAX score (>= 33), it was significantly higher after PCI than after CABG (adjusted FIR 2.61, 95% CI 1.32 to 5.16, p = 0.006). In conclusion, risk of PCI for serious adverse events seemed to be comparable to that after CABG in patients with ULMCAD with a low or intermediate SYNTAX score, whereas PCI compared with CABG was associated with a higher risk for serious adverse events in patients with a high SYNTAX score. (C) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:924-932)
- リンク情報
-
- DOI
- https://doi.org/10.1016/j.amjcard.2012.05.022
- CiNii Articles
- http://ci.nii.ac.jp/naid/120004874017
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/22721575
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000309487100002&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1016/j.amjcard.2012.05.022
- ISSN : 0002-9149
- CiNii Articles ID : 120004874017
- PubMed ID : 22721575
- Web of Science ID : WOS:000309487100002