論文

査読有り
2016年1月

Radiofrequency Ablation of Lung Tumors Using a Multitined Expandable Electrode: Impact of the Electrode Array Diameter on Local Tumor Progression

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
  • Hiroki Ihara
  • ,
  • Hideo Gobara
  • ,
  • Takao Hiraki
  • ,
  • Toshiharu Mitsuhashi
  • ,
  • Toshihiro Iguchi
  • ,
  • Hiroyasu Fujiwara
  • ,
  • Yusuke Matsui
  • ,
  • Junichi Soh
  • ,
  • Shinichi Toyooka
  • ,
  • Susumu Kanazawa

27
1
開始ページ
87
終了ページ
95
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jvir.2015.07.025
出版者・発行元
ELSEVIER SCIENCE INC

Purpose: To retrospectively investigate the impact of the electrode array diameter on local tumor progression after lung radiofrequency ablation.
Materials and Methods: This study included 651 lung tumors treated using multitined expandable electrodes and followed for 6 months. The mean long-axis tumor diameter was 12 mm +/- 7 (range, 2-42 mm). The difference between electrode array diameter and tumor diameter (DAT) was used to investigate the impact of the electrode array diameter. All tumors were classified into 2 groups according to various variables including DAT (>= 10 mm or < 10 mm). The primary technique efficacy rates were calculated using Kaplan-Meier analysis and compared between the 2 groups of each variable using the log-rank test. In addition, crude and multivariate multilevel survival analyses were performed by sequentially including DAT and the other variables in 5 models.
Results: The median DAT for 651 tumors was 12 mm (range, 15 to 24 mm). The technique efficacy rate was significantly lower in the < 10 mm DAT group than in the >= 10 nun group (P < .001). In the crude and multivariate multilevel survival analyses, < 10 mm DAT was a significant risk factor for local progression in all models except model 5 (P = .067). In the >= 10 mm group, the technique efficacy rates were riot significantly different-between the 2 >= 10 min DAT subgroups (ICY to < 15 mm DAT vs >= 15 mm DAT).
Conclusions: DAT is an important risk factor for local progression. We recommend an electrode that is >= 10 mm larger than the tumor diameter.

Web of Science ® 被引用回数 : 17

リンク情報
DOI
https://doi.org/10.1016/j.jvir.2015.07.025
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/26321016
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000367963600012&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.jvir.2015.07.025
  • ISSN : 1051-0443
  • eISSN : 1535-7732
  • PubMed ID : 26321016
  • Web of Science ID : WOS:000367963600012

エクスポート
BibTeX RIS