Satoshi Tsukamoto

Profile Information

Affiliation: National Institutes for Quantum and Radiological Science and Technology

Researcher number: 80510693
J-GLOBAL ID: 202001001884462420
researchmap Member ID: R000010036

Research Interests

Research Areas

Life sciences / Laboratory animal science / Animal Science, Reproductive Biology

Research History

Apr, 2021 - Present

研究統括, 量子生命・医学部門生物研究推進室, 量子科学技術研究開発機構

Papers

NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA

Yasuhiro Yamamoto, Haruka Chino, Satoshi Tsukamoto, Koji L. Ode, Hiroki R. Ueda, Noboru Mizushima

Nature Communications, 12(1), Dec, 2021 Peer-reviewed
Homeostatic regulation of lipid droplet content in mammalian oocytes and embryos.

Megumi Ibayashi, Ryutaro Aizawa, Junichiro Mitsui, Satoshi Tsukamoto

Reproduction (Cambridge, England), 162(6) R99-R109, Oct 28, 2021 Peer-reviewedCorresponding author
mRNA decapping factor Dcp1a is essential for embryonic growth in mice.

Megumi Ibayashi, Ryutaro Aizawa, Satoshi Tsukamoto

Biochemical and biophysical research communications, 555 128-133, May 28, 2021 Peer-reviewedCorresponding author
Organelle degradation in the lens by PLAAT phospholipases.

Hideaki Morishita, Tomoya Eguchi, Satoshi Tsukamoto, Yuriko Sakamaki, Satoru Takahashi, Chieko Saito, Ikuko Koyama-Honda, Noboru Mizushima

Nature, 592(7855) 634-638, Apr, 2021 Peer-reviewed
Impact of short-term high-fat feeding on lipid droplet content in mouse oocytes.

Ryutaro Aizawa, Megumi Ibayashi, Tomomi Hatakeyama, Takayuki Tatsumi, Satoshi Tsukamoto

The Journal of reproduction and development, 67(1) 73-77, Feb 15, 2021 Peer-reviewedCorresponding author
Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development.

Ryutaro Aizawa, Megumi Ibayashi, Takayuki Tatsumi, Atsushi Yamamoto, Toshiaki Kokubo, Naoyuki Miyasaka, Ken Sato, Shuntaro Ikeda, Naojiro Minami, Satoshi Tsukamoto

Development (Cambridge, England), 146(22), Nov 25, 2019 Peer-reviewedCorresponding author
How does the promoter of an oocyte-specific gene function in male germ cells?

Yuka Miki, Satoshi Tsukamoto, Naojiro Minami

The Journal of reproduction and development, 64(6) 463-468, Dec 14, 2018 Peer-reviewed
Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

Shinnosuke Honda, Yuka Miki, Yuya Miyamoto, Yu Kawahara, Satoshi Tsukamoto, Hiroshi Imai, Naojiro Minami

The Journal of reproduction and development, 64(4) 297-301, Aug 20, 2018 Peer-reviewed
Degradation of maternal factors during preimplantation embryonic development.

Satoshi Tsukamoto, Takayuki Tatsumi

The Journal of reproduction and development, 64(3) 217-222, Jun 22, 2018 Peer-reviewedCorresponding author
Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse.

Takayuki Tatsumi, Kaori Takayama, Shunsuke Ishii, Atsushi Yamamoto, Taichi Hara, Naojiro Minami, Naoyuki Miyasaka, Toshiro Kubota, Akira Matsuura, Eisuke Itakura, Satoshi Tsukamoto

Development (Cambridge, England), 145(4), Feb 23, 2018 Peer-reviewedCorresponding author
An Autophagic Flux Probe that Releases an Internal Control.

Takeshi Kaizuka, Hideaki Morishita, Yutaro Hama, Satoshi Tsukamoto, Takahide Matsui, Yuichiro Toyota, Akihiko Kodama, Tomoaki Ishihara, Tohru Mizushima, Noboru Mizushima

Molecular cell, 64(4) 835-849, Nov 17, 2016 Peer-reviewed
Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons.

Saori R Yoshii, Akiko Kuma, Takumi Akashi, Taichi Hara, Atsushi Yamamoto, Yoshitaka Kurikawa, Eisuke Itakura, Satoshi Tsukamoto, Hiroshi Shitara, Yoshinobu Eishi, Noboru Mizushima

Developmental cell, 39(1) 116-130, Oct 10, 2016 Peer-reviewed
Deficiencies in extrusion of the second polar body due to high calcium concentrations during in vitro fertilization in inbred C3H/He mice.

Yuki Ohta, Yoshikazu Nagao, Naojiro Minami, Satoshi Tsukamoto, Seiji Kito

Zygote (Cambridge, England), 24(4) 603-16, Aug, 2016 Peer-reviewed
Histone methyltransferase Smyd3 regulates early embryonic lineage commitment in mice.

Shinnosuke Suzuki, Yusuke Nozawa, Satoshi Tsukamoto, Takehito Kaneko, Hiroshi Imai, Naojiro Minami

Reproduction (Cambridge, England), 150(1) 21-30, Jul, 2015 Peer-reviewed
CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.

Shinnosuke Suzuki, Yusuke Nozawa, Satoshi Tsukamoto, Takehito Kaneko, Ichiro Manabe, Hiroshi Imai, Naojiro Minami

Development (Cambridge, England), 142(13) 2375-84, Jul 1, 2015 Peer-reviewed
Autophagic activity as an indicator for selecting good quality embryos.

Satoshi Tsukamoto

Reproductive medicine and biology, 14(2) 57-64, Apr, 2015 Peer-reviewedCorresponding author
Mitochondrial fission factor Drp1 maintains oocyte quality via dynamic rearrangement of multiple organelles.

Osamu Udagawa, Takaya Ishihara, Maki Maeda, Yui Matsunaga, Satoshi Tsukamoto, Natsuko Kawano, Kenji Miyado, Hiroshi Shitara, Sadaki Yokota, Masatoshi Nomura, Katsuyoshi Mihara, Noboru Mizushima, Naotada Ishihara

Current biology : CB, 24(20) 2451-8, Oct 20, 2014 Peer-reviewed
Disruption of Aspm causes microcephaly with abnormal neuronal differentiation.

Akira Fujimori, Kyoko Itoh, Shoko Goto, Hirokazu Hirakawa, Bing Wang, Toshiaki Kokubo, Seiji Kito, Satoshi Tsukamoto, Shinji Fushiki

Brain & development, 36(8) 661-9, Sep, 2014
Fertilization-induced autophagy in mouse embryos is independent of mTORC1.

Atsushi Yamamoto, Noboru Mizushima, Satoshi Tsukamoto

Biology of reproduction, 91(1) 7-7, Jul, 2014 Peer-reviewedCorresponding author
Fluorescence-based visualization of autophagic activity predicts mouse embryo viability.

Satoshi Tsukamoto, Taichi Hara, Atsushi Yamamoto, Seiji Kito, Naojiro Minami, Toshiro Kubota, Ken Sato, Toshiaki Kokubo

Scientific reports, 4 4533-4533, Mar 31, 2014 Peer-reviewedLead authorCorresponding author

Professional Memberships

Apr, 2009 - Present

https://www.jalas.jp/index.html
Jun, 2008 - Present

公益社団法人日本繁殖生物学会
Aug, 2002 - Present

日本分子生物学会
Sep, 2019

一般社団法人日本生殖医学会

Research Projects

卵子形成過程で合成される脂肪滴と卵子インテグリティの分子基盤に関する研究

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2021 - Mar, 2023

塚本智史
分解の視点で評価する卵の品質診断法の開発

ビジョナリーリサーチ（ステップ）, 武田科学振興財団研究助成金, Nov, 2018 - Mar, 2020

塚本智史
Physiological function and visualization of lipid droplets in mouse oocyte/embryo

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Tsukamoto Satoshi
Physiological and pathophysiological roles for autophagy and its molecular basis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2013 - Mar, 2018

Mizushima Noboru, MATSUMOTO Naomichi
Functional analysis of autophagy during spermatogenesis in mice

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, 2010 - 2012

TSUKAMOTO Satoshi, MINAMI Naojiro
Involvement of autophagy on sperm mitochondria degradation in mice

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2010 - 2011

TSUKAMOTO Satoshi, MINAMI Naojiro

Profile Information

Research Interests

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Research History

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