論文

査読有り
2017年7月

Proton Beam Therapy for Pediatric Brain Tumor

NEUROLOGIA MEDICO-CHIRURGICA
  • Masashi Mizumoto
  • ,
  • Yoshiko Oshiro
  • ,
  • Tetsuya Yamamoto
  • ,
  • Hidehiro Kohzuki
  • ,
  • Hideyuki Sakurai

57
7
開始ページ
343
終了ページ
355
記述言語
英語
掲載種別
DOI
10.2176/nmc.ra.2017-0003
出版者・発行元
JAPAN NEUROSURGICAL SOC

Cancer is a major cause of childhood death, with central nervous system (CNS) neoplasms being the second most common pediatric malignancy, following hematological cancer. Treatment of pediatric CNS malignancies requires multimodal treatment using a combination of surgery, chemotherapy, and radiotherapy, and advances in these treatments have given favorable results and longer survival. However, treatment-related toxicities have also occurred, particularly for radiotherapy, after which secondary cancer, reduced function of irradiated organs, and retarded growth are significant problems. Proton beam therapy (PBT) is a particle radiotherapy with excellent dose localization that permits treatment of liver and lung cancer by administration of a high dose to the tumor while minimizing damage to surrounding normal tissues. Thus, PBT has the potential advantages for pediatric cancer. In this context, we review the current knowledge on PBT for treatment of pediatric CNS malignancies.

Web of Science ® 被引用回数 : 24

リンク情報
DOI
https://doi.org/10.2176/nmc.ra.2017-0003
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28603224
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000409947700005&DestApp=WOS_CPL
ID情報
  • DOI : 10.2176/nmc.ra.2017-0003
  • ISSN : 0470-8105
  • eISSN : 1349-8029
  • PubMed ID : 28603224
  • Web of Science ID : WOS:000409947700005

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