論文

査読有り
2013年4月

Delayed Radiotherapy for Patients with Localized Prostate Cancer: Validation by Propensity Score Matching

ANTICANCER RESEARCH
  • Hidetsugu Nakayama
  • ,
  • Ayae Kanemoto
  • ,
  • Koji Kikuchi
  • ,
  • Katsuyuki Matsuki
  • ,
  • Mitsuro Tomobe
  • ,
  • Sadamu Tsukamoto
  • ,
  • Hitoshi Takeshima
  • ,
  • Yoshiko Oshiro
  • ,
  • Shinji Sugahara
  • ,
  • Koichi Tokuuye

33
4
開始ページ
1629
終了ページ
1633
記述言語
英語
掲載種別
研究論文(学術雑誌)
出版者・発行元
INT INST ANTICANCER RESEARCH

Aim: To retrospectively investigate the biochemical outcome following delayed radiotherapy in patients with prostate cancer. Patients and Methods: From July 2000 to November 2008, 144 consecutive patients with localized prostate cancer underwent radiotherapy and androgen-deprivation therapy. Biochemical progression-free survival was compared in patients who began radiotherapy >6 months (delayed group) with these who began months (non-delayed group) from diagnosis by biopsy. Treatment selection bias was adjusted by the propensity score method. Results: After a median follow-up of 64 months, the 5-year biochemical progression-free survival of the delayed and non-delayed groups was 87.4% (95% confidence interval, CI=69.7-95.1%) and 96.6% (95% CI=89.6-98.9%), respectively (p=0.03). Delayed radiotherapy was the only independent risk factor for biochemical progression (hazard ratio=3.97, 95% CI 1.07-14.7, p=0.04). The results were validated by propensity score analysis. Conclusion: Delaying radiotherapy by >6 months increases the risk of biochemical progression in patients with localized prostate cancer.

Web of Science ® 被引用回数 : 4

リンク情報
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23564807
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000317632200046&DestApp=WOS_CPL
ID情報
  • ISSN : 0250-7005
  • PubMed ID : 23564807
  • Web of Science ID : WOS:000317632200046

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