Shuji Wakatsuki

J-GLOBAL         Last updated: Mar 17, 2019 at 12:16
 
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Name
Shuji Wakatsuki
Affiliation
National Institute of Neuroscience, NCNP

Research Interests

 
 

Research Areas

 
 

Published Papers

 
Regulation of neuronal/axonal degeneration by ZNRF1 ubiquitin ligase.
Araki T. and Wakatsuki S.
   2018   [Refereed]
Inhibition of collapsin response mediator protein-2 phosphorylation ameliorates motor phenotype of ALS model mice expressing SOD1G93A.
Numata-Uematsu Y, Wakatsuki S, Nagano S, Shibata M, Sakai K, Ichinohe N, Mikoshiba K, Ohshima T, Yamashita N, Goshima Y, Araki T.
   2018   [Refereed]
Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms.
Imai S., Koyanagi M., Azimi Z., Nakazato Y. , Matsumoto M. , Ogihara T., Yonezawa A. , Omura T. , Nakagawa S. , Wakatsuki S. , Araki T. , Kaneko S., Nakagawa T., and Matsubara K.
7 5947   2017   [Refereed]
GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration.
Wakatsuki S. Tokunaga S., Shibata M., and Araki T.
216 477-493   2017   [Refereed]
Specific phospholipid scramblases are involved in exposure of phosphatidylserine, an "eat-me" signal for phagocytes, on degenerating axons
Wakatsuki S. and Araki T
Commun Integr Biol.   10 e1296615   2017   [Refereed]
Saito F., Wakatsuki S., Tokunaga S., Hujieda, H. and Araki T.
Sci Rep.   6 29856   2016   [Refereed]
Wakatsuki S. and Araki T
Commun Integr Biol.   9 e1143575   2016   [Refereed]

Conference Activities & Talks

 
Oxidative stress-dependent phosphorylation activates ZNRF1 ubiquitin ligase to induce neuronal apoptosis and Wallerian degeneration.
2015 Neuroscience Meeting   19 Oct 2015   
Role of ubiquitin proteasome system in axon degeneration: ZNRF1 E3 ubiquitin ligase promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation.
Neurodegenerative diseases conference in Cold Spring Harbor Laboratory   3 Dec 2014