湯澤 聡

A novel <i>BICD2</i> mutation of a patient with Spinal Muscular Atrophy Lower Extremity Predominant 2 

Intractable & Rare Diseases Research 10(2) 102-108 2021年5月31日  査読有り

Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation. 

The Journal of Biological Chemistry 294(51) 19655-19666 2019年12月  査読有り

Ric-8A-mediated stabilization of the trimeric G protein subunit Gαi is inhibited by pertussis toxin-catalyzed ADP-ribosylation. 

Biochemical and Biophysical Research Communications 483(3) 941-945 2017年2月  査読有り

Structural basis of cofactor-mediated stabilization and substrate recognition of the α-tubulin acetyltransferase αTAT1. 

The Biochemical Journal 467(1) 103-113 2015年4月  査読有り筆頭著者

Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN. 

Acta crystallographica. Section F, Structural biology communications 71(Pt 2) 175-183 2015年2月  査読有り

Ubiquitination of the heterotrimeric G protein α subunits Gαi2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A. 

Biochemical and Biophysical Research Communications 435(3) 414-419 2013年6月  査読有り

Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution. 

Biochemistry 51(20) 4157-4166 2012年5月  査読有り

Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN). 

Proceedings of the National Academy of Sciences of the United States of America 108(48) 19210-19215 2011年11月  査読有り筆頭著者

A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase. 

The Journal of Biological Chemistry 285(41) 31435-31445 2010年10月  査読有り

The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site. 

Cell 138(3) 514-524 2009年8月  査読有り

Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2. 

Biochemical and Biophysical Research Communications 383(3) 347-352 2009年6月  査読有り

The domain organization of p67phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes. 

Journal of Innate Immunity 1(6) 543-555 2009年  査読有り筆頭著者

Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor. 

Journal of Biomolecular NMR 42(3) 197-207 2008年11月  査読有り

Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization. 

Proceedings of the National Academy of Sciences of the United States of America 105(22) 7681-7686 2008年6月  査読有り

Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway. 

Molecular and Cellular Biology 27(19) 6903-6912 2007年10月  査読有り

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. 

Cell 130(2) 323-334 2007年7月  査読有り筆頭著者

Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding. 

The EMBO Journal 26(4) 1176-1186 2007年2月  査読有り

Crystallization and preliminary crystallographic analysis of p40phox, a regulatory subunit of NADPH oxidase. 

Acta crystallographica. Section F, Structural biology and crystallization communications 62(Pt 10) 1018-1020 2006年10月  査読有り

NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide. 

The Journal of Biological Chemistry 281(6) 3660-3668 2006年2月  査読有り