青沼達也 (Tatsuya Aonuma) - マイポータル

基本情報

所属: 旭川医科大学内科学講座循環器・腎臓内科学分野助教

学位: 博士課程(2016年6月旭川医科大学)

研究者番号: 90646001
ORCID iD: https://orcid.org/0000-0002-6838-2813
J-GLOBAL ID: 202401021026672441
researchmap会員ID: R000073320

経歴

2021年4月 - 現在

旭川医科大学, 助教
2016年7月 - 2021年3月

旭川医科大学, 客員教員（助教）
2012年4月 - 2016年6月

旭川医科大学, 大学院生（博士課程）

学歴

- 2016年6月

旭川医科大学, 医学研究科

論文

BACH2 links β1-adrenergic receptor/β-arrestin1 signaling to MIAT to inhibit cardiac fibroblast activation and cardiomyocyte apoptosis.

Bruno Moukette, Jian-Peng Teoh, Waleed J Hashmi, Satoshi Kawaguchi, Tatsuya Aonuma, Hamedane Moustapha, Steven S Welc, Simon J Conway, Suthat Liangpunsakul, Lei Yang …

Cell death discovery 2026年2月28日
Delayed Stanford type A aortic dissection after transcatheter aortic valve implantation with balloon-expandable valve: a case report.

Yudai Shiwaku, Tatsuya Aonuma, Yuya Kitani, Naoko Kawabata, Erika Saito, Akiho Minoshima, Toshiharu Takeuchi, Nobuhiro Mochizuki, Masahiro Tsutsui, Hiroyuki Kamiya …

Journal of surgical case reports 2025(11) rjaf875 2025年11月
Successful transcatheter mitral valve repair for mitral regurgitation complicating fulminant eosinophilic myocarditis: a case report.

Yudai Shiwaku, Tatsuya Aonuma, Yuya Kitani, Toshiharu Takeuchi, Nakagawa Naoki

European heart journal. Case reports 9(8) ytaf353 2025年8月
Periostin is a Pivotal Target of microRNA-150-5p in Cardiac Fibroblast Activation and Chronic Myocardial Infarction.

Taiki Hayasaka, Bruno Moukette, Marisa N Sepúlveda, Satoshi Kawaguchi, Tatsuya Aonuma, Hamedane Moustapha, Lei Yang, Meena S Madhur, Suthat Liangpunsakul, Il-Man Kim

JACC. Basic to translational science 10(8) 101330-101330 2025年7月25日
Fatal Outcome Due to Pulmonary Arterial Intramural Hematoma Associated With Stanford Type A Acute Aortic Dissection: A Case Report.

Yudai Shiwaku, Tatsuya Aonuma, Kanako Matsuda, Takahiro Shiokoshi, Naoki Nakagawa

Cureus 17(6) e85969 2025年6月
Cardiomyocyte-restricted MIAT deletion is sufficient to protect against murine myocardial infarction

Taiki Hayasaka, Satoshi Kawaguchi, Marisa N. Sepúlveda, Jian-peng Teoh, Bruno Moukette, Tatsuya Aonuma, Meena S. Madhur, Ankit A. Desai, Suthat Liangpunsakul, Simon J. Conway …

Cell Death Discovery 11(1) 2025年2月20日
A case of rapid rupture of a calcified amorphous tumor observed by echocardiography.

Kentaro Shirakura, Ryohei Ushioda, Masahiro Tsutsui, Shingo Kunioka, Nobuhiro Mochizuki, Tatsuya Aonuma, Naoko Kawabata, Erika Saitoh, Naoki Nakagawa, Hiroyuki Kamiya

Journal of surgical case reports 2025(2) rjaf064 2025年2月
MicroRNA-150 Deletion from Adult Myofibroblasts Augments Maladaptive Cardiac Remodeling Following Chronic Myocardial Infarction.

Satoshi Kawaguchi, Marisa N Sepúlveda, Jian-Peng Teoh, Taiki Hayasaka, Bruno Moukette, Tatsuya Aonuma, Hyun Cheol Roh, Meena S Madhur, Il-Man Kim

Biomolecules 14(12) 2024年12月22日
Inducible deletion of microRNA activity in kidney mesenchymal cells exacerbates renal fibrosis

Hirofumi Sakuma, Keisuke Maruyama, Tatsuya Aonuma, Yuya Kobayashi, Taiki Hayasaka, Kohei Kano, Satoshi Kawaguchi, Kei Ichi Nakajima, Jun Ichi Kawabe, Naoyuki Hasebe …

Scientific Reports 14(1) 2024年12月
Severe mitral regurgitation in non-hypertrophic cardiomyopathy caused by systolic anterior motion of the mitral valve

Tatsuya Aonuma, Naoko Kawabata, Ayumi Date, Erika Saito, Kazumi Akasaka, Hiroyuki Kamiya, Naoki Nakagawa

Journal of Medical Ultrasonics 2024年
SPRR1A is a key downstream effector of MiR-150 during both maladaptive cardiac remodeling in mice and human cardiac fibroblast activation

Satoshi Kawaguchi, Bruno Moukette, Marisa N. Sepúlveda, Taiki Hayasaka, Tatsuya Aonuma, Angela K. Haskell, Jessica Mah, Suthat Liangpunsakul, Yaoliang Tang, Simon J. Conway …

Cell Death and Disease 14(7) 2023年7月
Prostaglandin E<inf>2</inf> mediates the late phase of ischemic preconditioning in the heart via its receptor subtype EP<inf>4</inf>

Takayasu Kanno, Naoki Nakagawa, Tatsuya Aonuma, Jun ichi Kawabe, Koh ichi Yuhki, Naofumi Takehara, Naoyuki Hasebe, Fumitaka Ushikubi

Heart and Vessels 38(4) 606-613 2023年4月
MiR-150 blunts cardiac dysfunction in mice with cardiomyocyte loss of β<inf>1</inf>-adrenergic receptor/β-arrestin signaling and controls a unique transcriptome

Bruno Moukette, Satoshi Kawaguchi, Marisa N. Sepulveda, Taiki Hayasaka, Tatsuya Aonuma, Suthat Liangpunsakul, Lei Yang, Rohan Dharmakumar, Simon J. Conway, Il man Kim

Cell Death Discovery 8(1) 2022年12月
MiR-150 Attenuates Maladaptive Cardiac Remodeling Mediated by Long Noncoding RNA MIAT and Directly Represses Profibrotic Hoxa4

Tatsuya Aonuma, Bruno Moukette, Satoshi Kawaguchi, Nipuni P. Barupala, Marisa N. Sepúlveda, Kyle Frick, Yaoliang Tang, Maya Guglin, Subha V. Raman, Chenleng Cai …

Circulation: Heart Failure 15(4) E008686 2022年4月1日
Sarcopenia-derived exosomal micro-RNA 16-5p disturbs cardio-repair via a pro-apoptotic mechanism in myocardial infarction in mice

Taiki Hayasaka, Naofumi Takehara, Tatsuya Aonuma, Kohei Kano, Kiwamu Horiuchi, Naoki Nakagawa, Hiroki Tanaka, Jun ichi Kawabe, Naoyuki Hasebe

Scientific Reports 11(1) 2021年12月
Cardiomyocyte microRNA-150 confers cardiac protection and directly represses proapoptotic small proline–rich protein 1A

Tatsuya Aonuma, Bruno Moukette, Satoshi Kawaguchi, Nipuni P. Barupala, Marisa N. Sepúlveda, Christopher Corr, Yaoliang Tang, Suthat Liangpunsakul, R. Mark Payne, Monte S. Willis …

JCI Insight 6(18) 2021年9月22日
Interactions between noncoding RNAs as epigenetic regulatory mechanisms in cardiovascular diseases

Bruno Moukette, Nipuni P. Barupala, Tatsuya Aonuma, Marisa Sepulveda, Satoshi Kawaguchi, Il man Kim

Methods in Cell Biology 166 309-348 2021年1月
Capillary-resident EphA7⁺ pericytes are multipotent cells with anti-ischemic effects through capillary formation

Yuri Yoshida, Maki Kabara, Kohei Kano, Kiwamu Horiuchi, Taiki Hayasaka, Yui Tomita, Naofumi Takehara, Akiho Minoshima, Tatsuya Aonuma, Keisuke Maruyama …

Stem Cells Translational Medicine 9(1) 120-130 2020年1月1日
The antioxidant and DNA-repair enzyme apurinic/apyrimidinic endonuclease 1 limits the development of tubulointerstitial fibrosis partly by modulating the immune system

Keisuke Maruyama, Naoki Nakagawa, Tatsuya Aonuma, Yukihiro Saito, Taiki Hayasaka, Kohei Kano, Kiwamu Horiuchi, Naofumi Takehara, Jun ichi Kawabe, Naoyuki Hasebe

Scientific Reports 9(1) 2019年12月1日
Circular noncoding RNAs as potential therapies and circulating biomarkers for cardiovascular diseases review-article

Ahmed S. Bayoumi, Tatsuya Aonuma, Jian Peng Teoh, Yao Liang Tang, Il Man Kim

Acta Pharmacologica Sinica 39(7) 1100-1109 2018年7月1日

もっとみる

MISC

潜因性脳梗塞の卵円孔開存診断における心電図Crochetage Patternの有用性

河端奈穂子, 坂本央, 青沼達也, 齋藤江里香, 竹内利治, 佐藤伸之, 中川直樹

日本臨床検査医学会誌 72(補冊) 244-244 2024年10月
Apurinic/apyrimidinic Endonuclease/redox Factor-1 Gene Enhances Anti-apoptotic Function of Cardiac Progenitor Cells via TAK1-Activation and Promotes Cardiac Regeneration in Myocardial Infarction

Tatsuya Aonuma, Naofumi Takehara, Keisuke Maruyama, Maki Kabara, Motoki Matsuki, Atsushi Yamauchi, Junichi Kawabe, Naoyuki Hasebe

CIRCULATION 132 2015年11月
Ninjurin1, a Novel Regulatory Factor of Pericytes to Interact With Endothelial Cells, Mediates the Circulation Recovery in the Hind Limb Ischemia

Motoki Matsuki, Jun-ichi Kawabe, Tatsuya Aonuma, Maki Kabara, Atsushi Yamauchi, Kohei Shimamura, Akiho Minoshima, Naofumi Takehara, Yukihiro Saito, Naoyuki Hasebe

CIRCULATION 130 2014年11月

共同研究・競争的資金等の研究課題

乳癌患者におけるトラスツズマブ関連心毒性の新規バイオマーカーlncRNAの探索

日本学術振興会科学研究費助成事業若手研究 2022年4月 - 2025年3月

青沼達也
抗HER２薬関連心毒性にける新規バイオマーカーlong noncoding RNAの探索

民間財団等 2024年4月 - 2025年3月
糖尿病循環障害：血流動態的変動指標の確立

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2025年3月

滝山由美, 中村匡徳, 世良俊博, 青沼達也
IGF-2陽性iPS細胞由来心筋前駆細胞の樹立と機能解析及び心筋移植効果の検討

日本学術振興会科学研究費助成事業若手研究(B) 2017年4月 - 2022年3月

青沼達也
トラスツズマブ関連心毒性におけるlong noncoding RNAの役割に関する検討英文題目名

民間財団等 2021年11月 - 2021年11月