Takeshi Goya

Profile Information

Affiliation: Kyushu University

Researcher number: 30884754
J-GLOBAL ID: 202001006820276110
researchmap Member ID: R000008854

Research Interests

肝疾患肝臓

Research Areas

Life sciences / Gastroenterology /

Research History

Apr, 2020 - Present

助教, 肝臓・膵臓・胆道内科, 九州大学病院
Apr, 2014 - Mar, 2015

医師, 肝臓内科, 麻生飯塚病院
Apr, 2013 - Mar, 2014

医師, 肝臓内科, 国立病院機構小倉医療センター
Apr, 2011 - Mar, 2013

内科医師, 内科, 九州労災病院
Apr, 2010 - Mar, 2011

研修医, 九州大学病院
Apr, 2009 - Mar, 2010

研修医, 雪の聖母会聖マリア病院

Education

Apr, 2015 - Mar, 2020

大学院医学系学府器官発生再生学分野, 九州大学
Apr, 2003 - Mar, 2009

医学科, 医学部, 九州大学

Papers

Microcirculatory disturbance in acute liver injury is triggered by IFNγ-CD40 axis.

Miho Kurokawa, Takeshi Goya, Motoyuki Kohjima, Masatake Tanaka, Sadahiro Iwabuchi, Shigeyuki Shichino, Satoshi Ueha, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi …

Journal of inflammation (London, England), 21(1) 23-23, Jun 21, 2024
Acute kidney injury is an unfavorable prognostic factor in acute liver failure and is associated with tumor necrosis factor-alpha.

Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuki Azuma, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Miho Kurokawa, Masaki Kato, Motoyuki Kohjima …

Medicine, 102(45) e35931, Nov 10, 2023
Clinicopathologic Features of Adult-onset Still's Disease Complicated by Severe Liver Injury.

Miho Kurokawa, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Takeshi Goya, Masatake Tanaka, Motoyuki Kohjima, Yoshihiro Ogawa

Internal medicine (Tokyo, Japan), Jun 21, 2023
FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation

Shun Fujinuma, Hirokazu Nakatsumi, Hideyuki Shimizu, Shigeaki Sugiyama, Akihito Harada, Takeshi Goya, Masatake Tanaka, Motoyuki Kohjima, Masatomo Takahashi, Yoshihiro Izumi …

Cell Reports, 42(5) 112530-112530, May, 2023
Transcatheter arterial steroid injection therapy improves the prognosis of patients with acute liver failure.

Akifumi Kuwano, Tasuku Okui, Motoyuki Kohjima, Miho Kurokawa, Takeshi Goya, Masatake Tanaka, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro …

Medicine, 102(10) e33090, Mar 10, 2023
Elevated Pancreatic Enzymes Associated with Acute Liver Injury Were Mediated by Tumor Necrosis Factor-Alpha Signaling

Takeshi Goya, Miho Kurokawa, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro, Hideo Suzuki, Masatake Tanaka, Masaki Kato …

Hepatitis Monthly, 22(1), Aug 24, 2022 Peer-reviewedLead author
Direct Conversion of Human Endothelial Cells Into Liver Cancer‐Forming Cells Using Nonintegrative Episomal Vectors

Takeshi Goya, Kenichi Horisawa, Miyako Udono, Yasuyuki Ohkawa, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki

Hepatology Communications, 6(7) 1725-1740, Jul, 2022 Peer-reviewedLead author
Corticosteroid suppresses urea-cycle-related gene expressions in ornithine transcarbamylase deficiency.

Koji Imoto, Masatake Tanaka, Takeshi Goya, Tomomi Aoyagi, Motoi Takahashi, Miho Kurokawa, Shigeki Tashiro, Masaki Kato, Motoyuki Kohjima, Yoshihiro Ogawa

BMC gastroenterology, 22(1) 144-144, Mar 28, 2022
The Efficacy of Tofogliflozin on Metabolic Dysfunction-Associated Fatty Liver Disease

Takeshi Goya, Koji Imoto, Shigeki Tashiro, Tomomi Aoyagi, Motoi Takahashi, Miho Kurokawa, Hideo Suzuki, Masatake Tanaka, Masaki Kato, Motoyuki Kohjima …

Gastroenterology Insights, 13(1) 20-26, Jan 15, 2022 Peer-reviewedLead author
Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation.

Shigeki Tashiro, Masatake Tanaka, Takeshi Goya, Tomomi Aoyagi, Miho Kurokawa, Koji Imoto, Akifumi Kuwano, Motoi Takahashi, Hideo Suzuki, Motoyuki Kohjima …

Toxicology and applied pharmacology, 434 115817-115817, Jan 1, 2022
The Combination of Nucleotide Analog Therapy and Steroid Pulse Therapy for Acute HBV Infection Effectively Promotes HBV Clearance

Takeshi Goya, Tomoyuki Kurashige, Miho Kurokawa, Masatake Tanaka, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro, Hideo Suzuki, Masaki Kato …

Gastroenterology Insights, 13(1) 1-8, Dec 31, 2021 Peer-reviewedLead author
Discriminant equation using mucosally expressed cytokines and transcription factor for making definite diagnosis of inflammatory bowel disease unclassified

Hiroaki Okuno, Haruei Ogino, Eikichi Ihara, Kei Nishioka, Yoshimasa Tanaka, Takatoshi Chinen, Motoyuki Kohjima, Takamasa Oono, Masatake Tanaka, Takeshi Goya …

BMC Gastroenterology, 21(1) 73-73, Dec, 2021
Upregulated expression of hypoxia reactive genes in peripheral blood mononuclear cells from chronic liver disease patients.

Akifumi Kuwano, Masatake Tanaka, Hideo Suzuki, Miho Kurokawa, Koji Imoto, Shigeki Tashiro, Takeshi Goya, Motoyuki Kohjima, Masaki Kato, Yoshihiro Ogawa

Biochemistry and biophysics reports, 27 101068-101068, Sep, 2021
Hypoxic hepatitis with marked elevation of serum ferritin probably due to activation of intrahepatic macrophages: another form of hypoxic hepatitis hitherto not reported?

M Tanaka, T Goya, H Suzuki, M Takahashi, K Imoto, M Kurokawa, S Tashiro, A Kuwano, S Okada, M Kato …

Acta Gastro Enterologica Belgica, 84(2) 317-320, Jun, 2021
Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma

Hideo Suzuki, Motoyuki Kohjima, Masatake Tanaka, Takeshi Goya, Shinji Itoh, Tomoharu Yoshizumi, Masaki Mori, Mariko Tsuda, Motoi Takahashi, Miho Kurokawa …

Canadian Journal of Gastroenterology and Hepatology, 2021 1-13, Feb 18, 2021
Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells

Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno …

Nature Communications, 11(1), Dec, 2020 Peer-reviewed
Efficacy of tolvaptan for the patients with advanced hepatocellular carcinoma

Masayuki Miyazaki, Masayoshi Yada, Kosuke Tanaka, Takeshi Senjyu, Takeshi Goya, Kenta Motomura, Motoyuki Kohjima, Masaki Kato, Akihide Masumoto, Kazuhiro Kotoh

World Journal of Gastroenterology, 23(29) 5379-5379, Aug, 2017 Peer-reviewed
Novel methods for the treatment of liver fibrosis using in vivo direct reprogramming technology

Takeshi Goya, Atsushi Suzuki

Stem Cell Investigation, 3 92-92, Dec 9, 2016 Peer-reviewed
Portal Vein Thrombosis Repeatedly Observed in a Cirrhotic Patient with Antiphospholipid Antibody Syndrome

Mari Ohe, Taishi Mutsuki, Takeshi Goya, Shinsaku Yamashita, Takeaki Satoh, Motoyuki Kohjima, Masaki Kato

Fukuoka Igaku Zasshi, 107(10) 185-190, Oct, 2016 Peer-reviewed

Misc.

肝がん診療のupdate:標準化と個別化実臨床における進行肝細胞がんに対するアテゾリズマブ+ベバシズマブ治療の有効性と安全性

上田哲弘, 杉本理恵, 荒武良総, 佐藤丈顕, 原田林, 田中正剛, 大穂有恒, 國吉政美, 多田靖哉, 千住猛士 …

日本消化器病学会九州支部例会・日本消化器内視鏡学会九州支部例会プログラム・抄録集, 118回・112回 69-69, Dec, 2021

Research Projects

Extracellular Trapsに着目した肝障害の炎症プロセスの解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2022 - Mar, 2026

合谷孟
The role of non-parenchymal cells on the pathogenesis for NASH

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
The study about the mechanism of postmenopausal non-alcoholic steatohepatitis using single-cell RNA sequencing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
The resesarch on platicity and heterogeneity of hepatocyte in acute liver injury

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Sep, 2020 - Mar, 2022

Goya Takeshi

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

Misc.

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