2010年7月
Efficacy of photodynamic therapy with topical 5-aminolevulinic acid using intense pulsed light for Bowen's disease
JOURNAL OF DERMATOLOGY
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- 巻
- 37
- 号
- 7
- 開始ページ
- 623
- 終了ページ
- 628
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/j.1346-8138.2010.00850.x
- 出版者・発行元
- WILEY-BLACKWELL
Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) is reported to be an effective and safe treatment for superficial non-melanoma skin cancers. We have developed an photodynamic therapy with topical delta-aminolevulinic acid (ALA-PDT) protocol using intense pulsed light (IPL) for treating Bowen's disease (BD). Three patients diagnosed with BD by skin biopsy were recruited in this study. They received IPL treatment after 3 h of occlusive dressing with application of ALA. This protocol was repeated every 2 weeks for a total of five sessions. The treated areas did not show any signs of BD for more than 1 year; therefore, it appeared that the affected areas showed improvement in all the patients. No patients withdrew from the study because of side-effects. ALA-PDT with IPL as a light source is well tolerated by patients and is beneficial for treating BD.
- リンク情報
- ID情報
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- DOI : 10.1111/j.1346-8138.2010.00850.x
- ISSN : 0385-2407
- PubMed ID : 20629828
- Web of Science ID : WOS:000279405300006