論文

査読有り
2015年

Estimation of crosstalk in LED fNIRS by photon propagation Monte Carlo simulation

BIOPHOTONICS JAPAN 2015
  • Takayuki Iwano
  • ,
  • Shinji Umeyama

9792
記述言語
英語
掲載種別
研究論文(国際会議プロシーディングス)
DOI
10.1117/12.2204999
出版者・発行元
SPIE-INT SOC OPTICAL ENGINEERING

fNIRS (functional near-Infrared spectroscopy) can measure brain activity non-invasively and has advantages such as low cost and portability. While the conventional fNIRS has used laser light, LED light fNIRS is recently becoming common in use. Using LED for fNIRS, equipment can be more inexpensive and more portable. LED light, however, has a wider illumination spectrum than laser light, which may change crosstalk between the calculated concentration change of oxygenated and deoxygenated hemoglobins. The crosstalk is caused by difference in light path length in the head tissues depending on wavelengths used. We conducted Monte Carlo simulations of photon propagation in the tissue layers of head (scalp, skull, CSF, gray matter, and white matter) to estimate the light path length in each layers. Based on the estimated path lengths, the crosstalk in fNIRS using LED light was calculated. Our results showed that LED light more increases the crosstalk than laser light does when certain combinations of wavelengths were adopted. Even in such cases, the crosstalk increased by using LED light can be effectively suppressed by replacing the value of extinction coefficients used in the hemoglobin calculation to their weighted average over illumination spectrum.


リンク情報
DOI
https://doi.org/10.1117/12.2204999
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000369013700019&DestApp=WOS_CPL
URL
http://orcid.org/0000-0001-8173-8901

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