論文

国際誌
2021年3月14日

Complications of Poly-l-Lactic Acid and Polyglycolic Acid (PLLA/PGA) Osteosynthesis Systems for Maxillofacial Surgery: A Retrospective Clinical Investigation.

Polymers
  • Yuhei Matsuda
  • ,
  • Masaaki Karino
  • ,
  • Tatsuo Okui
  • ,
  • Takahiro Kanno

13
6
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/polym13060889

Two second-generation PLLA/PGA bioresorbable osteosynthetic plate systems for oral and maxillofacial surgery are available in Japan. The two systems have different PLLA-PGA component ratios (RapidSorb®, 85:15; Lactosorb®, 82:18) and plate and screw shapes. We conducted a retrospective study to compare our clinical evaluation and examine the incidence of postoperative complications between the two plate systems. A retrospective survey was conducted in 148 patients (midfacial fracture/trauma (68.2%) and dentofacial deformity patients (31.8%); males (54.7%); median age, 37.5 years) treated using maxillofacial osteosynthetic plate systems. The complications included plate exposure (7.4%), infection, (2.7%), and plate breakage (0.7%). Multivariate logistic regression analysis showed a significant correlation between sex (female), plate system (Lactosorb®), number of plates, and pyriform aperture and periorbital sites of plate placement (p < 0.05). Additionally, the propensity score-adjusted model showed a significant correlation between Lactosorb® and postoperative complications (odds ratio 1.007 (95% confidence interval, 1.001-1.055), p < 0.01). However, the two plate systems showed a low incidence rate of complications, and the plate integration and survivability were similar using 2.0-mm or 1.5-mm resorbable plate regardless of the plate system. Our findings suggest that female sex and a greater number of plates are risk factors for postoperative complications, whereas pyriform aperture and periorbital plate placements reduce the risk.

リンク情報
DOI
https://doi.org/10.3390/polym13060889
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33799342
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001587
ID情報
  • DOI : 10.3390/polym13060889
  • PubMed ID : 33799342
  • PubMed Central 記事ID : PMC8001587

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