論文

査読有り
2017年1月

Relative Importance of Central and Peripheral Adiposities on Cardiometabolic Variables in Females: A Japanese Population-Based Study

JOURNAL OF CLINICAL DENSITOMETRY
  • Katsuyasu Kouda
  • ,
  • Namiraa Dongmei
  • ,
  • Junko Tamaki
  • ,
  • Masayuki Iki
  • ,
  • Takahiro Tachiki
  • ,
  • Etsuko Kajita
  • ,
  • Yoshimi Nakatani
  • ,
  • Kazuhiro Uenishi
  • ,
  • Sadanobu Kagamimori
  • ,
  • Yoshiko Kagawa
  • ,
  • Hideo Yoneshima

20
1
開始ページ
58
終了ページ
65
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jocd.2016.04.004
出版者・発行元
ELSEVIER SCIENCE INC

In epidemiological studies, there is little evidence regarding the relative impact of central adiposity and peripheral adiposity on cardiometabolic risk factors, especially in Asian populations. This study investigated associations between central-to-peripheral fat ratios and cardiometabolic variables using data from a population based study of Japanese women. The source population was composed of 1800 women aged 50 yr or older at the 15th- to 16th-yr follow-up survey of the Japanese Population-Based Osteoporosis Cohort Study. This study analyzed cross-sectional data from 998 women for whom complete information about body fat variables according to dual-energy X-ray absorptiometry, cardiometabolic variables, and potential confounding factors was available. Both before and after adjusting for potential confounding factors, trunk-to-appendicular fat ratios showed significant (p < 0.05) correlations with brachial ankle pulse wave velocity, serum lipids, and hemoglobin A1c levels. Relationships between fat ratios and cardiometabolic variables were independent of relationships between fat volumes (in whole body or in trunk) and cardiometabolic variables. Furthermore, relationships between trunk-to-appendicular fat ratios and cardiometabolic variables were observed among women in the lowest tertile of total body fat (brachial ankle pulse wave velocity, beta = 0.08; high-density lipoprotein cholesterol, beta = -0.32; low-density lipoprotein cholesterol, beta = 0.15; and hemoglobin A1C, beta = 0.16; p < 0.05, respectively). Central adiposity is more related to cardiometabolic variables than peripheral adiposity. Information on central-to-peripheral fat ratios is particularly valuable for the evaluation of relatively thin Japanese women.


リンク情報
DOI
https://doi.org/10.1016/j.jocd.2016.04.004
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27216083
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000395849400009&DestApp=WOS_CPL

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