論文

査読有り
2019年1月

Muscle strength is associated with bone health independently of muscle mass in postmenopausal women: the Japanese population-based osteoporosis study.

Journal of bone and mineral metabolism
  • Takahiro Tachiki
  • ,
  • Katsuyasu Kouda
  • ,
  • Namiraa Dongmei
  • ,
  • Junko Tamaki
  • ,
  • Masayuki Iki
  • ,
  • Jun Kitagawa
  • ,
  • Naonobu Takahira
  • ,
  • Yuho Sato
  • ,
  • Etsuko Kajita
  • ,
  • Yuki Fujita
  • ,
  • Akiko Yura
  • ,
  • Sadanobu Kagamimori

37
1
開始ページ
53
終了ページ
59
記述言語
英語
掲載種別
DOI
10.1007/s00774-017-0895-7

There are conflicting reports on whether muscle strength is associated with bone mineral density (BMD) independently of muscle mass. Here, we examined the association between muscle strength and BMD in a representative population of Japanese women. Cross-sectional data from 680 postmenopausal women, who were participants in the 15th-year follow-up survey of the Japanese Population-based Osteoporosis cohort study, were analyzed. Areal BMD (aBMD) at the femoral neck and lumbar spine, whole-body bone mineral density, and appendicular skeletal muscle mass (ASM, kg) were measured by dual-energy X-ray absorptiometry. The ASM index (ASMI, kg/m2) was calculated as ASM divided by height squared (m2). Grip strength (kg) was measured as an indicator of muscle strength. Grip strength showed significantly (P < 0.05) positive relationships with aBMDs at several skeletal sites after adjusting for ASMI and age (standardized partial regression coefficient (β) = 0.102 at femoral neck, β = 0.126 at lumbar spine). Adjusted means of aBMD at the femoral neck and lumbar spine showed significant increasing trends from the lowest to highest tertile of grip strength. Our findings indicate that muscle strength is associated with aBMD at several sites independently of muscle mass in Japanese postmenopausal women. Thus, postmenopausal women with strong muscle strength tend to have a healthy bone status regardless of muscle size.

リンク情報
DOI
https://doi.org/10.1007/s00774-017-0895-7
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29282553

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