2011年12月
Evaluation of BPA uptake in clear cell sarcoma (CCS) in vitro and development of an in vivo model of CCS for BNCT studies
APPLIED RADIATION AND ISOTOPES
- 巻
- 69
- 号
- 12
- 開始ページ
- 1713
- 終了ページ
- 1716
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.apradiso.2011.02.006
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
Clear cell sarcoma (CCS), a rare malignant tumor with a predilection for young adults, is of poor prognosis. Recently however, boron neutron capture therapy (BNCT) with the use of p-borono-L-phenylalanine (BPA) for malignant melanoma has provided good results. CCS also produces melanin; therefore, the uptake of BPA is the key to the application of BNCT to CCS. We describe, for the first time, the high accumulation of boron in CCS and the CCS tumor-bearing animal model generated for BNCT studies. (c) 2011 Elsevier Ltd. All rights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.apradiso.2011.02.006
- ISSN : 0969-8043
- PubMed ID : 21354804
- Web of Science ID : WOS:000297426000023