安達健朗 (Tatsuo Adachi) - マイポータル

基本情報

J-GLOBAL ID: 202101005736368957
researchmap会員ID: R000019370

論文

RaptScore: a large language model-based algorithm for versatile aptamer evaluation.

Akira Kimura-Yamazaki, Tatsuo Adachi, Shigetaka Nakamura, Yoshikazu Nakamura, Michiaki Hamada

Nucleic acids research 54(2) 2026年1月14日
RaptGen-Assisted Generation of an RNA/DNA Hybrid Aptamer against SARS-CoV-2 Spike Protein.

Tatsuo Adachi, Shigetaka Nakamura, Akiya Michishita, Daiki Kawahara, Mizuki Yamamoto, Michiaki Hamada, Yoshikazu Nakamura

Biochemistry 2024年3月8日
Generative aptamer discovery using RaptGen

Natsuki Iwano, Tatsuo Adachi, Kazuteru Aoki, Yoshikazu Nakamura, Michiaki Hamada

Nature Computational Science 2(6) 378-386 2022年6月
RaptRanker: in silico RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information.

Ryoga Ishida, Tatsuo Adachi, Aya Yokota, Hidehito Yoshihara, Kazuteru Aoki, Yoshikazu Nakamura, Michiaki Hamada

Nucleic acids research 48(14) e82 2020年8月20日
Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application.

Tatsuo Adachi, Yoshikazu Nakamura

Molecules (Basel, Switzerland) 24(23) 2019年11月21日
Niemann-Pick disease type C2 protein induces autophagy and inhibits growth in FM3A breast cancer cells.

Tatsuo Adachi, Yasuhiko Matsumoto, Yoshinori Inagaki, Kazuhisa Sekimizu

Drug discoveries & therapeutics 9(4) 282-8 2015年8月
Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane.

Hiroshi Hamamoto, Makoto Urai, Kenichi Ishii, Jyunichiro Yasukawa, Atmika Paudel, Motoki Murai, Takuya Kaji, Takefumi Kuranaga, Kenji Hamase, Takashi Katsu …

Nature chemical biology 11(2) 127-33 2015年2月
Niemann-Pick disease type C2 protein induces triglyceride accumulation in silkworm and mammalian cell lines.

Tatsuo Adachi, Kenichi Ishii, Yasuhiko Matsumoto, Yohei Hayashi, Hiroshi Hamamoto, Kazuhisa Sekimizu

The Biochemical journal 459(1) 137-47 2014年4月1日
Induction of virulence gene expression in Staphylococcus aureus by pulmonary surfactant.

Kenichi Ishii, Tatsuo Adachi, Jyunichiro Yasukawa, Yutaka Suzuki, Hiroshi Hamamoto, Kazuhisa Sekimizu

Infection and immunity 82(4) 1500-10 2014年4月
Identification of a Serratia marcescens virulence factor that promotes hemolymph bleeding in the silkworm, Bombyx mori.

Kenichi Ishii, Tatsuo Adachi, Takashi Hara, Hiroshi Hamamoto, Kazuhisa Sekimizu

Journal of invertebrate pathology 117 61-7 2014年3月
Serratia marcescens suppresses host cellular immunity via the production of an adhesion-inhibitory factor against immunosurveillance cells.

Kenichi Ishii, Tatsuo Adachi, Hiroshi Hamamoto, Kazuhisa Sekimizu

The Journal of biological chemistry 289(9) 5876-88 2014年2月28日
Insect cytokine paralytic peptide activates innate immunity via nitric oxide production in the silkworm Bombyx mori.

Kenichi Ishii, Tatsuo Adachi, Hiroshi Hamamoto, Tadahiro Oonishi, Manabu Kamimura, Katsutoshi Imamura, Kazuhisa Sekimizu

Developmental and comparative immunology 39(3) 147-53 2013年3月
Serratia marcescens induces apoptotic cell death in host immune cells via a lipopolysaccharide- and flagella-dependent mechanism.

Kenichi Ishii, Tatsuo Adachi, Katsutoshi Imamura, Shinya Takano, Kimihito Usui, Kazushi Suzuki, Hiroshi Hamamoto, Takeshi Watanabe, Kazuhisa Sekimizu

The Journal of biological chemistry 287(43) 36582-92 2012年10月19日
Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae.

Kenichi Ishii, Hiroshi Hamamoto, Katsutoshi Imamura, Tatsuo Adachi, Mikio Shoji, Koji Nakayama, Kazuhisa Sekimizu

The Journal of biological chemistry 285(43) 33338-33347 2010年10月22日

共同研究・競争的資金等の研究課題

細菌リポプロテインの脂質修飾機構の解明

日本学術振興会科学研究費助成事業研究活動スタート支援 2016年8月 - 2017年3月

安達健朗
カイコ体液因子ＰｒｏｍｏｔｉｎｇＰｒｏｔｅｉｎによる脂肪細胞分化誘導機構の解明

日本学術振興会科学研究費助成事業特別研究員奨励費 2012年4月 - 2015年3月

安達健朗