論文

査読有り
2004年4月

Lack of monosynaptic corticomotoneuronal EPSPs in rats: Disynaptic EPSPs mediated via reticulospinal neurons and polysynaptic EPSPs via segmental interneurons

JOURNAL OF NEUROPHYSIOLOGY
  • B Alstermark
  • ,
  • J Ogawa
  • ,
  • T Isa

91
4
開始ページ
1832
終了ページ
1839
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1152/jn.00820.2003
出版者・発行元
AMER PHYSIOLOGICAL SOC

In the rat, some findings have been taken to suggest the existence of monosynaptic corticomotoneuronal (CM) connections. Because this connection is believed to be largely responsible for the ability to make independent digit movements in primates and man, it has been inferred that the monosynaptic CM connection in the rat is likewise important for skilled prehension. Comparison of intra- and extracellular recordings from forelimb motoneurons in anesthetized rats, revealed no monosynaptic CM excitatory postsynaptic potentials (EPSPs). The fastest descending excitation in forelimb motoneurons was disynaptically mediated via a corticoreticulospinal pathway and slowly conducted excitation via corticospinal fibers and segmental interneurons. The findings stress the importance of di- and trisynaptic excitatory corticofugal pathways to forelimb motoneurons in the control of skilful digit movements.

リンク情報
DOI
https://doi.org/10.1152/jn.00820.2003
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000220086100036&DestApp=WOS_CPL
ID情報
  • DOI : 10.1152/jn.00820.2003
  • ISSN : 0022-3077
  • Web of Science ID : WOS:000220086100036

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