2004年
Switching between cortical and subcortical sensorimotor pathways
BRAIN MECHANISMS FOR THE INTEGRATION OF POSTURE AND MOVEMENT
- ,
- 巻
- 143
- 号
- 開始ページ
- 299
- 終了ページ
- 305
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/S0079-6123(03)43029-X
- 出版者・発行元
- ELSEVIER SCIENCE BV
It is well known that the reaction times of visually guided saccades exhibit a bimodal distribution. Those with extremely short reaction times are termed 'express saccades'. In their case, visual input appears to be transformed into motor output via a 'short-loop', brainstem-mediated pathway. In contrast, those with longer reaction times are called,regular saccades'. The latter are presumably executed via a cortically mediated, 'long-loop' sensorimotor pathway. The 'gate' that switches signal flow between the short and long loop is thought to be located in between the superficial and deeper layers of the superior colliculus (SC). Nonlinear signal amplification mechanisms, which operate in local circuits of the deeper SC layers may underlie this gating function, with switching of the gate regulated in a context-dependent manner by inputs from the cerebral cortex and basal ganglia.
- リンク情報
- ID情報
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- DOI : 10.1016/S0079-6123(03)43029-X
- ISSN : 0079-6123
- PubMed ID : 14653174
- Web of Science ID : WOS:000187421300029