Takaho Endoh

Profile Information

Affiliation: 理化学研究所

J-GLOBAL ID: 201501018968457588
researchmap Member ID: B000246476

Research Interests

Research Areas

Research History

2010 - 2011

研究員, 生命情報基盤研究部門, 独立行政法人理化学研究所

Papers

Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm.

Yasuhide Ohinata, Takaho A Endo, Hiroki Sugishita, Takashi Watanabe, Yusuke Iizuka, Yurie Kawamoto, Atsunori Saraya, Mami Kumon, Yoko Koseki, Takashi Kondo …

Science (New York, N.Y.), 375(6580) 574-578, Feb 4, 2022
PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.

Mitsuhiro Endoh, Takaho A Endo, Jun Shinga, Katsuhiko Hayashi, Anca Farcas, Kit-Wan Ma, Shinsuke Ito, Jafar Sharif, Tamie Endoh, Naoko Onaga …

eLife, 6, Mar 17, 2017
Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.

Jafar Sharif, Takaho A Endo, Manabu Nakayama, Mohammad M Karimi, Midori Shimada, Kayoko Katsuyama, Preeti Goyal, Julie Brind'Amour, Ming-An Sun, Zhixiong Sun …

Cell stem cell, 19(1) 81-94, Jul 7, 2016
Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (vol 31, pg 351, 2011)

Xiangzhi Li, Kyo-ichi Isono, Daisuke Yamada, Takaho A. Endo, Mitsuhiro Endoh, Jun Shinga, Yoko Mizutani-Koseki, Arie P. Otte, Miguel Casanova, Hiroshi Kitamura …

MOLECULAR AND CELLULAR BIOLOGY, 34(14) 2773-2773, Jul, 2014 Peer-reviewed
Polycomb Potentiates Meis2 Activation in Midbrain by Mediating Interaction of the Promoter with a Tissue-Specific Enhancer

Takashi Kondo, Kyoichi Isono, Kaori Kondo, Takaho A. Endo, Shigeyoshi Itohara, Miguel Vidal, Haruhiko Koseki

DEVELOPMENTAL CELL, 28(1) 94-101, Jan, 2014 Peer-reviewed
SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing

Kyoichi Isono, Takaho A. Endo, Manching Ku, Daisuke Yamada, Rie Suzuki, Jafar Sharif, Tomoyuki Ishikura, Tetsuro Toyoda, Bradley E. Bernstein, Haruhiko Koseki

DEVELOPMENTAL CELL, 26(6) 565-577, Sep, 2013 Peer-reviewed
Role of SOX17 in hematopoietic development from human embryonic stem cells.

Yaeko Nakajima-Takagi, Mitsujiro Osawa, Motohiko Oshima, Haruna Takagi, Satoru Miyagi, Mitsuhiro Endoh, Takaho A Endo, Naoya Takayama, Koji Eto, Tetsuro Toyoda …

Blood, 121(3) 447-58, Jan 17, 2013
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.

Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA …

PLoS genetics, 8(7) e1002774, Jul, 2012 Peer-reviewed
RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells

Kaori Hisada, Carmen Sanchez, Takaho A. Endo, Mitsuhiro Endoh, Monica Roman-Trufero, Jafar Sharif, Haruhiko Koseki, Miguel Vidal

MOLECULAR AND CELLULAR BIOLOGY, 32(6) 1139-1149, Mar, 2012 Peer-reviewed
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

Yuta Mishima, Satoru Miyagi, Atsunori Saraya, Masamitsu Negishi, Mitsuhiro Endoh, Takaho A Endo, Tetsuro Toyoda, Jun Shinga, Takuo Katsumoto, Tetsuhiro Chiba …

Blood, 118(9) 2443-53, Sep 1, 2011
Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells

Motohiko Oshima, Mitsuhiro Endoh, Takaho A. Endo, Tetsuro Toyoda, Yaeko Nakajima-Takagi, Fumihiro Sugiyama, Haruhiko Koseki, Michael Kyba, Atsushi Iwama, Mitsujiro Osawa

BLOOD, 117(15) E142-E150, Apr, 2011 Peer-reviewed
Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes

Xiangzhi Li, Kyo-ichi Isono, Daisuke Yamada, Takaho A. Endo, Mitsuhiro Endoh, Jun Shinga, Yoko Mizutani-Koseki, Arie P. Otte, Miguel Casanova, Hiroshi Kitamura …

MOLECULAR AND CELLULAR BIOLOGY, 31(2) 351-364, Jan, 2011 Peer-reviewed
Polycomb-dependent regulation for differentiation programs of stem cells and progenitors

Haruhiko Koseki, Mitsuhiro Endoh, Takaho A. Endo

DIFFERENTIATION, 80 S9-S10, Nov, 2010 Peer-reviewed
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.

Endoh M, Endo TA, Endoh T, Fujimura Y, Ohara O, Toyoda T, Otte AP, Okano M, Brockdorff N, Vidal M …

Development (Cambridge, England), 135(8) 1513-1524, Apr 15, 2008 Peer-reviewed

Misc.

非典型的ポリコーム群MBLR複合体による減数分裂遺伝子のエピジェネティック制御

遠藤充浩, 遠藤充浩, 遠藤多美枝, 遠藤高帆, 信賀順, 古関明彦

日本生化学会大会(Web), 88th 2T17-03(2P1003) (WEB ONLY)-03(2P1003)], Dec, 2015
iPS細胞技術を利用したNKT細胞再生とがん免疫療法

山田大輔, 伊豫田智典, ビスカルド・ラウル, 遠藤高帆, 小原收, 藤井眞一郎, 古関明彦

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [2P1053]-[2P1053], Dec, 2015
腸内細菌が産生する酪酸は制御性T細胞への分化を誘導する

古澤之裕, 尾畑佑樹, 福田真嗣, 遠藤高帆, 大野博司, 長谷耕二

日本薬学会年会要旨集(CD-ROM), 134th(3) ROMBUNNO.30Y-PM07-91, Mar, 2014
MBLR‐PRC1ポリコーム複合体による減数分裂遺伝子のエピジェネティック制御

遠藤充浩, 遠藤高帆, 遠藤多美枝, 信賀順, 古関明彦

日本分子生物学会年会プログラム・要旨集(Web), 37th 3LBA-25 (WEB ONLY), 2014
潰瘍性大腸炎粘膜固有層における少数のT細胞及びマクロファージ/樹状細胞を用いたエピゲノム解析

大坪武史, 遠藤高帆, 豊田哲郎, 大島健志朗, 萩原輝記, 稲垣匡子, 河村裕, 小西文雄, 矢野秀朗, 斉藤幸夫 …

日本生化学会大会(Web), 85th 3P-749 (WEB ONLY), 2012
高速シーケンサーを用いたシロイヌナズナにおけるエピゲノム解析の実際

KIM Jong‐Myong, 遠藤高帆, 石田順子, 豊田哲郎, 関原明

植物の生長調節, 46(2) 142-148, Dec 20, 2011
ポリコーム群Ring1A/Bによるヒストン修飾を介した幹細胞制御

遠藤充浩, 遠藤高帆, 古関明彦

生化学, ROMBUNNO.2S2P-1, Sep 25, 2009

Research Projects

ポリコム群による抑制ドメインの複製機構の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Jun, 2019 - Mar, 2024

古関明彦, 遠藤高帆
Commensal microbiota maintains gut homeostasis through epigenetic modification

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Aug, 2012 - Mar, 2014

FURUSAWA Yukihiro, ENDO Takaho
Genome-wide identification of genes for anorexia and their cascade analysis on disease development by functional study

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, 2007 - 2011

INOKO Hidetoshi, OKA Akira, ENDOH Takaho, OHTSUKA Masato, YOSHIHARA Eisaku, HIRAYAMA Noriaki
Dissecting molecular mechanisms mediated by Polycomb group proteins in maintenance and differentiation of ES cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2008 - 2010

KOSEKI HARUHIKO, TAKAHO Endoh, MITSUHIRO Endoh, JUN Shinga, FUJIMURA Yu-Ichi

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Research History

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