TAKAGI Masatoshi

J-GLOBAL         Last updated: Dec 6, 2019 at 02:58
 
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Name
TAKAGI Masatoshi
Affiliation
Tokyo Medical and Dental University
Section
Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Pediatrics and Developmental Biology
Job title
Associate Professor
Degree
Ph.D.(Juntendo University)
Research funding number
10406267

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
Nov 2019
 - 
Today
Associate Professor, Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Pediatrics and Developmental Biology, Tokyo Medical and Dental University
 
Jul 2018
 - 
Oct 2019
Associate Professor, Graduate School of Medical and Dental Sciences - - -, Tokyo Medical and Dental University
 
Jul 2015
 - 
Jun 2018
Associate Professor, Graduate School of Medical and Dental Sciences Endowed Departments Department of Pediatrics, Perinatal and Maternal Medicine, Tokyo Medical and Dental University
 
Apr 2010
 - 
Jun 2015
Junior Associate Professor, Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Pediatrics and Developmental Biology, Tokyo Medical and Dental University
 
Apr 2007
 - 
Mar 2010
Assistant Professor, Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Pediatrics and Developmental Biology, Tokyo Medical and Dental University
 

Published Papers

 
Setsuko Hasegawa, Satoko Kumada, Naoyuki Tanuma, Atsumi Tsuji-Hosokawa, Ayako Kashimada, Tomoko Mizuno, Kengo Moriyama, Yuji Sugawara, Ikuko Shirai, Yohane Miyata, Hiroya Nishida, Hideaki Mashimo, Takeshi Hasegawa, Takatoshi Hosokawa, Hiroaki Hisakawa, Mitsugu Uematsu, Akio Fujine, Rie Miyata, Hiroshi Sakuma, Kenichi Kashimada, Kohsuke Imai, Tomohiro Morio, Masaharu Hayashi, Shuki Mizutani, Masatoshi Takagi
Pediatr Neurol   100 60-66   Nov 2019   [Refereed]
Ataxia telangiectasia is an autosomal recessive disorder characterized by cerebellar ataxia, telangiectases, immune defects, and a predisposition to malignancy. Quality of life is severely impaired by neurological symptoms. However, curative optio...
Sutani A, Miyakawa Y, Tsuji-Hosokawa A, Nomura R, Nakagawa R, Nakajima K, Maru M, Aoki Y, Takasawa K, Takagi M, Imai K, Kashimada K, Morio T
Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology   28(4) 105-112   Oct 2019   [Refereed]
Atsushi Watanabe, Takeshi Inukai, Keiko Kagami, Masako Abe, Masatoshi Takagi, Takashi Fukushima, Hiroko Fukushima, Toru Nanmoku, Kiminori Terui, Tatsuya Ito, Tsutomu Toki, Etsuro Ito, Junya Fujimura, Hiroaki Goto, Mikiya Endo, Thomas Look, Mark Kamps, Masayoshi Minegishi, Junko Takita, Toshiya Inaba, Hiroyuki Takahashi, Akira Ohara, Daisuke Harama, Tamao Shinohara, Shinpei Somazu, Hiroko Oshiro, Koshi Akahane, Kumiko Goi, Kanji Sugita
Cancer Med   8(11) 5274-5288   Sep 2019   [Refereed]
t(17;19)(q21-q22;p13), responsible for TCF3-HLF fusion, is a rare translocation in childhood B-cell precursor acute lymphoblastic leukemia(BCP-ALL). t(1;19)(q23;p13), producing TCF3-PBX1 fusion, is a common translocation in childhood BCP-ALL. Prog...
Tomoko Mizuno, Ayako Kashimada, Toshihiro Nomura, Kengo Moriyama, Haruna Yokoyama, Setsuko Hasegawa, Masatoshi Takagi, Shuki Mizutani
Brain Dev   41(7) 630-633   Aug 2019   [Refereed]
Spinocerebellar ataxia type 5 (SCA5), a dominant spinocerebellar ataxia is caused by spectrin beta nonerythrocytic 2 gene (SPTBN2) mutation. It typically consists of a slow progressive cerebellar ataxia with an onset principally in adulthood. Here...
Akihiro Hoshino, Hirokazu Kanegane, Masanori Nishi, Ikuya Tsuge, Kiriko Tokuda, Ichiro Kobayashi, Kohsuke Imai, Tomohiro Morio, Masatoshi Takagi
Clin Immunol   203 9-13   Jun 2019   [Refereed]
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is one of the inborn errors of immunity, characterized by impaired function of the regulatory T cells. Clinical manifestations of IPEX syndrome are characterized by va...

Misc

 
Takeshi Isoda, Tomohiro Morio, Masatoshi Takagi
Cancer Sci   110(8) 2328-2336   Aug 2019   [Refereed]
Changes of nuclear localization of lineage-specific genes from a transcriptionally inert to permissive environment are a crucial step in establishing the identity of a cell. Noncoding RNA transcription-mediated genome folding and activation of tar...
[Primary immunodeficiencies and hematological malignancies].
Kanegane H, Hoshino A, Takagi M
[Rinsho ketsueki] The Japanese journal of clinical hematology   59(11) 2459-2467   Nov 2018
Hirokazu Kanegane, Akihiro Hoshino, Tsubasa Okano, Takahiro Yasumi, Taizo Wada, Hidetoshi Takada, Satoshi Okada, Motoi Yamashita, Tzu-Wen Yeh, Ryuta Nishikomori, Masatoshi Takagi, Kohsuke Imai, Hans D Ochs, Tomohiro Morio
Allergol Int   67(1) 43-54   Jan 2018   [Refereed]
Primary immunodeficiencies (PIDs) are a heterogeneous group of inherited diseases of the immune system. The definite diagnosis of PID is ascertained by genetic analysis; however, this takes time and is costly. Flow cytometry provides a rapid and h...
Masatoshi Takagi
Int J Hematol   106(3) 450-453   Apr 2017   [Refereed]
DNA damage is a serious threat to cellular homeostasis. Damaged DNA leads to genomic instability, mutation, senescence, and/or cell death. DNA damage triggers a cellular response called the DNA damage response (DDR), followed by activation of the ...
Masatoshi Takagi, Kevin Urayama
The Japanese Journal of Clinical Hematology   57(7) 891-899   Jul 2016   [Refereed]
Numerous efforts have been made to elucidate the roles of individual genetic background factors in the risk of childhood acute lymphoblastic leukemia. Most have taken the form of case-control studies focusing on specific candidate gene polymorphis...

Conference Activities & Talks

 
Intrinsically Vancomycin resistant enterococcal (Enterococcus gallinarum) meningitis occurred early after hematopoietic stem cell transplantation for activated PI3K delta syndrome type2
16 Nov 2019   
Succesful case of donor lymphocyte infusion for refractory T cell acute lymphoblastic leukemia which lead to one year of remission
16 Nov 2019   
Pay attention to selective Immunoglobulin G2 deficiency - a case of Invasive pneumococcal infection after allogenic hematopietic stem cell transplantation
16 Nov 2019   
Usefulness of respiratory infection early diagnosis with multiplex PCR method for immunocompromised patients
16 Nov 2019   
A case with relapsed acute lymphoblastic leukemia treated with blinatumomab under the active GVHD after unrelated bone marrow transplantation
15 Nov 2019