論文

国際誌
2020年3月

Two cases of oligometastatic castration-resistant prostate cancer detected by diffusion-weighted whole-body imaging with background body signal suppression.

IJU case reports
  • Yuki Shimizu
  • ,
  • Nobuyuki Nakajima
  • ,
  • Kentaro Nagao
  • ,
  • Masahiro Nitta
  • ,
  • Masanori Hasegawa
  • ,
  • Yoshiaki Kawamura
  • ,
  • Toshiki Kazama
  • ,
  • Sunao Shoji
  • ,
  • Taro Takahara
  • ,
  • Akira Miyajima

3
2
開始ページ
65
終了ページ
68
記述言語
英語
掲載種別
DOI
10.1002/iju5.12146

Introduction: Treatment for oligometastasis in prostate cancer has changed from systemic therapy to metastatic lesion-targeted therapy. Early detection of metastatic lesions and assessment of the treatment response have become very important. Therefore, we started to perfume assessments with whole-body magnetic resonance imaging, especially diffusion-weighted imaging with background body signal suppression, as a modality to detect metastasis in patients with prostate cancer. Case presentation: We encountered two cases of castration-resistant prostate cancer in which oligometastasis was detected by diffusion-weighted imaging with background body signal suppression. Metastasis-directed therapy was initiated for to treat the lesions in each case. The treatment was effective for disease control and symptom relief. Diffusion-weighted imaging with background body signal suppression could detect new lesions at an early phase and delineate changes in lesions immediately after therapy. Conclusion: Diffusion-weighted imaging with background body signal suppression enables early decision-making for metastasis-directed therapy compared with conventional imaging modalities. Further, metastasis-directed therapy targeting oligometastatic lesions detected by diffusion-weighted imaging with background body signal suppression may improve patients' overall survival and quality of life.

リンク情報
DOI
https://doi.org/10.1002/iju5.12146
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32743473
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292150

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