Gou Takahashi

High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9

Gou Takahashi, Minato Maeda, Kayoko Shinozaki, Gakuro Harada, Saburo Ito, Yuichiro Miyaoka

Sep 19, 2024

Fusion of histone variants to Cas9 suppresses non-homologous end joining.

Tomoko Kato-Inui, Gou Takahashi, Terumi Ono, Yuichiro Miyaoka

PloS one, 19(5) e0288578, 2024

Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.

Gou Takahashi, Yuichiro Miyaoka

STAR protocols, 4(3) 102364-102364, Jun 16, 2023

Genome editing is induced in a binary manner in single human cells.

Gou Takahashi, Daiki Kondo, Minato Maeda, Yuji Morishita, Yuichiro Miyaoka

iScience, 25(12) 105619-105619, Dec 22, 2022

Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations.

Ryo Takahashi, Gou Takahashi, Yuichi Kameyama, Masahiro Sato, Masato Ohtsuka, Kenta Wada

International journal of molecular sciences, 23(19), Oct 6, 2022

Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson’s disease-specific hepatocytes

Dan Song, Gou Takahashi, Yun-Wen Zheng, Mami Matsuo-Takasaki, Jingyue Li, Miho Takami, Yuri An, Yasuko Hemmi, Natsumi Miharada, Tsuyoshi Fujioka …

Human Molecular Genetics, 31(21) 3652-3671, Apr 7, 2022

Rapid, precise quantification of large DNA excisions and inversions by ddPCR.

Hannah L Watry, Carissa M Feliciano, Ketrin Gjoni, Gou Takahashi, Yuichiro Miyaoka, Bruce R Conklin, Luke M Judge

Scientific reports, 10(1) 14896-14896, Sep 10, 2020

Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system.

Saaki Tamura, Yukiko Yasuoka, Hiromi Miura, Gou Takahashi, Masahiro Sato, Masato Ohtsuka

Experimental animals, 69(3) 287-294, Aug 5, 2020

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 with improved proof-reading enhances homology-directed repair.

Tomoko Kato-Inui, Gou Takahashi, Szuyin Hsu, Yuichiro Miyaoka

Nucleic acids research, 46(9) 4677-4688, May 18, 2018

Pde6brd1 mutation modifies cataractogenesis in Foxe3rct mice.

Kenta Wada, Junichi Saito, Midori Yamaguchi, Yuta Seki, Masamune Furugori, Gou Takahashi, Yasumasa Nishito, Hiroshi Matsuda, Hiroshi Shitara, Yoshiaki Kikkawa

Biochemical and biophysical research communications, 496(1) 231-237, Jan 29, 2018

A novel missense mutation of Mip causes semi-dominant cataracts in the Nat mouse.

Gou Takahashi, Sayaka Hasegawa, Yukiko Fukutomi, Chihiro Harada, Masamune Furugori, Yuta Seki, Yoshiaki Kikkawa, Kenta Wada

Experimental animals, 66(3) 271-282, Aug 5, 2017

GONAD and Easy (Isi)-CRISPR: novel mouse genome engineering tools

Masato Ohtsuka, Hiromi Miura, Gou Takahashi, Rolen Quadros, Masahiro Sato, Channabasavaiah B. Gurumurthy

TRANSGENIC RESEARCH, 25(2) 214-215, Apr, 2016 Peer-reviewed

GONAD: A Novel CRISPR/Cas9 Genome Editing Method that Does Not Require Ex Vivo Handling of Embryos.

Channabasavaiah B Gurumurthy, Gou Takahashi, Kenta Wada, Hiromi Miura, Masahiro Sato, Masato Ohtsuka

Current protocols in human genetics, 88 15.8.1-15.8.12, Jan 1, 2016

GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice.

Gou Takahashi, Channabasavaiah B Gurumurthy, Kenta Wada, Hiromi Miura, Masahiro Sato, Masato Ohtsuka

Scientific reports, 5 11406-11406, Jun 22, 2015

Mouse Genome Editing Using the CRISPR/Cas System.

Donald W Harms, Rolen M Quadros, Davide Seruggia, Masato Ohtsuka, Gou Takahashi, Lluis Montoliu, Channabasavaiah B Gurumurthy

Current protocols in human genetics, 83 15.7.1-27, Oct 1, 2014

Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice.

Kenta Wada, Yoshibumi Matsushima, Tomoki Tada, Sayaka Hasegawa, Yo Obara, Yasuhiro Yoshizawa, Gou Takahashi, Hiroshi Hiai, Midori Shimanuki, Sari Suzuki …

PloS one, 9(10) e111432, 2014

A deletion in a cis element of Foxe3 causes cataracts and microphthalmia in rct mice.

Kenta Wada, Yukiko Y Maeda, Kei Watanabe, Tatsuya Oshio, Takuya Ueda, Gou Takahashi, Michinari Yokohama, Junichi Saito, Yuta Seki, Sumiyo Takahama …

Mammalian genome : official journal of the International Mammalian Genome Society, 22(11-12) 693-702, Dec, 2011

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