高橋-山城恵生 (Kei Takahashi-Yamashiro) - マイポータル

Ikumi Miyazaki, Kelvin K. Tsao, Takuya Terai, Kei Takahashi-Yamashiro, Robert E. Campbell

bioRxiv 2026年3月8日

Development of a photostable pH biosensor based on mStayGold

Michael Chang, Kei Takahashi-Yamashiro, Takuya Terai, Robert E. Campbell, Kelvin K. Tsao

bioRxiv 2026年3月8日

Interplay between CD33 and TREM2 in Alzheimer's Disease: Potential Mechanistic Insights into Microglial Function in Amyloid Pathology.

Elizabeth T Akinluyi, Kei Takahashi-Yamashiro, Meghan G Connolly, Wayne W Poon, Matthew S Macauley

ACS chemical neuroscience 2025年12月12日

An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function

Zeinab Jame-Chenarboo, Edward N. Schmid, Madeline Crichton, Kei Takahashi-Yamashiro, Guilherme M. Lima, Liany Luna-Dulcey, Jaesoo Jung, Sabine Ivison, Chris D., St. Lauren …

Science Advances 11(46) 2025年11月12日査読有り

A sensitive orange fluorescent calcium ion indicator for imaging neural activity

Abhi Aggarwal, Heather A. Baker, Céline D. Dürs, I-Wen Chen, Pablo de Chambrier, Julia Marie Gonzales, Jonathan S. Marvin, Milène Vandal, Torgny Lundberg, Kenryo Sakoi …

bioRxiv 2025年7月31日

High-performance genetically-encoded green and red fluorescent biosensors for pyruvate.

Shosei Imai, Saaya Hario, Carl Suerte, Issei Yamaguchi, Kenryo Sakoi, Adam Thuen, Brekken Meznarich, Mikhail Drobizhev, Takuya Terai, Kei Takahashi-Yamashiro …

bioRxiv : the preprint server for biology 2025年7月5日

OCT-2 Is Associated With Pro-Metastatic Epigenomic Properties of Triple-Negative Breast Cancer Cells.

Kazuki Ogikubo, Jun Nishida, Kei Takahashi-Yamashiro, Masato Morikawa, Shogo Ehata, Tetsuro Watabe, Kohei Miyazono, Daizo Koinuma

Cancer science 2025年5月14日査読有り

Roles for Siglec-glycan interactions in regulating immune cells.

Sung-Yao Lin, Edward N Schmidt, Kei Takahashi-Yamashiro, Matthew S Macauley

Seminars in immunology 77 101925-101925 2024年12月19日査読有り

Alzheimer's disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice.

Ghazaleh Eskandari-Sedighi, Madeline Crichton, Sameera Zia, Erik Gomez-Cardona, Leonardo M Cortez, Zain H Patel, Kei Takahashi-Yamashiro, Chris D St Laurent, Gaurav Sidhu, Susmita Sarkar …

Molecular neurodegeneration 19(1) 42-42 2024年5月27日査読有り

Tissue clearing method in visualization of cancer progression and metastasis

Kei Takahashi-Yamashiro, Kohei Miyazono

Upsala Journal of Medical Sciences 129 2024年4月9日査読有り

High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate.

Saaya Hario, Giang N T Le, Hikaru Sugimoto, Kei Takahashi-Yamashiro, Suguru Nishinami, Hirofumi Toda, Selene Li, Jonathan S Marvin, Shinya Kuroda, Mikhail Drobizhev …

ACS central science 10(2) 402-416 2024年2月28日査読有り

Biosensor Optimization Using a Förster Resonance Energy Transfer Pair Based on mScarlet Red Fluorescent Protein and an mScarlet-Derived Green Fluorescent Protein.

Khyati Gohil, Sheng-Yi Wu, Kei Takahashi-Yamashiro, Yi Shen, Robert E Campbell

ACS sensors 2023年1月24日査読有り

The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria

Arthur Bassot, Junsheng Chen, Kei Takahashi-Yamashiro, Megan C. Yap, Christine Silvia Gibhardt, Giang N.T. Le, Saaya Hario, Yusuke Nasu, Jack Moore, Tomas Gutiérrez …

Cell Reports 42(1) 111899-111899 2023年1月査読有り

Quantification of Intracellular Citrate Concentrations with Genetically Encoded Biosensors

Yufeng Zhao, Kei Takahashi-Yamashiro, Yi Shen, Robert E. Campbell

Methods in Molecular Biology 247-258 2022年9月16日

An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis.

Kei Takahashi, Ko Abe, Shimpei I Kubota, Noriaki Fukatsu, Yasuyuki Morishita, Yasuhiro Yoshimatsu, Satoshi Hirakawa, Yoshiaki Kubota, Tetsuro Watabe, Shogo Ehata …

Nature communications 13(1) 5239-5239 2022年9月12日査読有り筆頭著者

Visualization of the cancer cell cycle by tissue‐clearing technology using the Fucci reporter system

Kei Takahashi, Ryo Tanabe, Shogo Ehata, Shimpei I. Kubota, Yasuyuki Morishita, Hiroki R. Ueda, Kohei Miyazono

Cancer Science 112(9) 3796-3809 2021年7月7日査読有り筆頭著者

Establishment of bioluminescent imaging model using murine T cell lymphoma susceptive to NK cell-dependent immune-surveillance

Toshiyuki Fujiwara, Kiho Miyazato, Kei Takahashi, Yoshihiro Hayakawa

Journal of Immunological Methods 491 112993-112993 2021年4月査読有り

Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing

Shimpei I. Kubota, Kei Takahashi, Tomoyuki Mano, Katsuhiko Matsumoto, Takahiro Katsumata, Shoi Shi, Kazuki Tainaka, Hiroki R. Ueda, Shogo Ehata, Kohei Miyazono

Communications Biology 4(1) 2021年3月5日査読有り

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation

Sau Yee Kok, Hiroko Oshima, Kei Takahashi, Mizuho Nakayama, Kazuhiro Murakami, Hiroki R. Ueda, Kohei Miyazono, Masanobu Oshima

Nature Communications 12(1) 2021年2月8日査読有り

Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing

Kei Takahashi, Shimpei I. Kubota, Shogo Ehata, Hiroki R. Ueda, Kohei Miyazono

STAR Protocols 1(3) 100191-100191 2020年12月18日査読有り筆頭著者

高橋-山城恵生

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