高橋-山城恵生 (Kei Takahashi-Yamashiro) - マイポータル

Tissue clearing method in visualization of cancer progression and metastasis

Kei Takahashi-Yamashiro, Kohei Miyazono

Upsala Journal of Medical Sciences 129 2024年4月9日査読有り

High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate.

Saaya Hario, Giang N T Le, Hikaru Sugimoto, Kei Takahashi-Yamashiro, Suguru Nishinami, Hirofumi Toda, Selene Li, Jonathan S Marvin, Shinya Kuroda, Mikhail Drobizhev …

ACS central science 10(2) 402-416 2024年2月28日査読有り

Biosensor Optimization Using a Förster Resonance Energy Transfer Pair Based on mScarlet Red Fluorescent Protein and an mScarlet-Derived Green Fluorescent Protein.

Khyati Gohil, Sheng-Yi Wu, Kei Takahashi-Yamashiro, Yi Shen, Robert E Campbell

ACS sensors 2023年1月24日査読有り

The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria

Arthur Bassot, Junsheng Chen, Kei Takahashi-Yamashiro, Megan C. Yap, Christine Silvia Gibhardt, Giang N.T. Le, Saaya Hario, Yusuke Nasu, Jack Moore, Tomas Gutiérrez …

Cell Reports 42(1) 111899-111899 2023年1月査読有り

Quantification of Intracellular Citrate Concentrations with Genetically Encoded Biosensors

Yufeng Zhao, Kei Takahashi-Yamashiro, Yi Shen, Robert E. Campbell

Methods in Molecular Biology 247-258 2022年9月16日

An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis.

Kei Takahashi, Ko Abe, Shimpei I Kubota, Noriaki Fukatsu, Yasuyuki Morishita, Yasuhiro Yoshimatsu, Satoshi Hirakawa, Yoshiaki Kubota, Tetsuro Watabe, Shogo Ehata …

Nature communications 13(1) 5239-5239 2022年9月12日査読有り筆頭著者

Visualization of the cancer cell cycle by tissue‐clearing technology using the Fucci reporter system

Kei Takahashi, Ryo Tanabe, Shogo Ehata, Shimpei I. Kubota, Yasuyuki Morishita, Hiroki R. Ueda, Kohei Miyazono

Cancer Science 112(9) 3796-3809 2021年7月7日査読有り筆頭著者

Establishment of bioluminescent imaging model using murine T cell lymphoma susceptive to NK cell-dependent immune-surveillance

Toshiyuki Fujiwara, Kiho Miyazato, Kei Takahashi, Yoshihiro Hayakawa

Journal of Immunological Methods 491 112993-112993 2021年4月査読有り

Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing

Shimpei I. Kubota, Kei Takahashi, Tomoyuki Mano, Katsuhiko Matsumoto, Takahiro Katsumata, Shoi Shi, Kazuki Tainaka, Hiroki R. Ueda, Shogo Ehata, Kohei Miyazono

Communications Biology 4(1) 2021年3月5日査読有り

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation

Sau Yee Kok, Hiroko Oshima, Kei Takahashi, Mizuho Nakayama, Kazuhiro Murakami, Hiroki R. Ueda, Kohei Miyazono, Masanobu Oshima

Nature Communications 12(1) 2021年2月8日査読有り

Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing

Kei Takahashi, Shimpei I. Kubota, Shogo Ehata, Hiroki R. Ueda, Kohei Miyazono

STAR Protocols 1(3) 100191-100191 2020年12月18日査読有り筆頭著者

Neurotensin receptor 1 signaling promotes pancreatic cancer progression

Kei Takahashi, Shogo Ehata, Kensuke Miyauchi, Yasuyuki Morishita, Keiji Miyazawa, Kohei Miyazono

Molecular Oncology 15(1) 151-166 2020年11月20日査読有り筆頭著者

Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis

Jun Nishida, Yusaku Momoi, Kosuke Miyakuni, Yusuke Tamura, Kei Takahashi, Daizo Koinuma, Kohei Miyazono, Shogo Ehata

Nature Cell Biology 22(4) 465-475 2020年3月23日査読有り

Tyrosine kinase Eph receptor A6 sensitizes glioma-initiating cells towards bone morphogenetic protein-induced apoptosis

Erna Raja, Masato Morikawa, Jun Nishida, Ryo Tanabe, Kei Takahashi, Howard J. Seeherman, Nobuhito Saito, Tomoki Todo, Kohei Miyazono

Cancer Science 110(11) 3486-3496 2019年11月1日査読有り

Palbociclib enhances activin‐SMAD‐induced cytostasis in estrogen receptor‐positive breast cancer

Mayumi Harada, Masato Morikawa, Takayuki Ozawa, Mai Kobayashi, Yusuke Tamura, Kei Takahashi, Masahiko Tanabe, Keiichiro Tada, Yasuyuki Seto, Kohei Miyazono …

Cancer Science 110(1) 209-220 2018年11月16日査読有り

Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents

Kazuki Tainaka, Tatsuya C. Murakami, Etsuo A. Susaki, Chika Shimizu, Rie Saito, Kei Takahashi, Akiko Hayashi-Takagi, Hiroshi Sekiya, Yasunobu Arima, Satoshi Nojima …

Cell Reports 24(8) 2196-2210.e9 2018年8月21日査読有り

Lung‐resident natural killer cells control pulmonary tumor growth in mice

Yutaka Yamamoto, Kiho Miyazato, Kei Takahashi, Naoki Yoshimura, Hideaki Tahara, Yoshihiro Hayakawa

Cancer Science 109(9) 2670-2676 2018年7月12日査読有り

Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells

Kei Takahashi, Shogo Ehata, Daizo Koinuma, Yasuyuki Morishita, Manabu Soda, Hiroyuki Mano, Kohei Miyazono

Oncogene 37(21) 2757-2772 2018年5月1日査読有り筆頭著者

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y 12 in platelets

Miki Kamiyama, Toshiaki Shirai, Shogo Tamura, Katsue Suzuki-Inoue, Shogo Ehata, Kei Takahashi, Kohei Miyazono, Yoshihiro Hayakawa, Takehiro Sato, Kohsuke Takeda …

Cell Death and Differentiation 24(12) 2066-2076 2017年12月1日査読有り

Proteasome Inhibitor–Loaded Micelles Enhance Antitumor Activity Through Macrophage Reprogramming by NF-κB Inhibition

Hailiang Wu, Anqi Tao, John D. Martin, Sabina Quader, Xueying Liu, Kei Takahashi, Louise Hespel, Yutaka Miura, Yoshihiro Hayakawa, Tatsuro Irimura …

Journal of Pharmaceutical Sciences 106(9) 2438-2446 2017年9月査読有り

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