論文

査読有り 国際誌
2021年4月

Establishment of bioluminescent imaging model using murine T cell lymphoma susceptive to NK cell-dependent immune-surveillance

Journal of Immunological Methods
  • Toshiyuki Fujiwara
  • ,
  • Kiho Miyazato
  • ,
  • Kei Takahashi
  • ,
  • Yoshihiro Hayakawa

491
開始ページ
112993
終了ページ
112993
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jim.2021.112993

Although the importance of NK cells as immune effector cells in controlling growth and metastatic dissemination of tumor cells has been widely recognized, it is unclear whether NK cells in different organs similarly control tumor cell growth and metastasis. In the present study, we established a bioluminescent imaging model of mouse T cell lymphoma cells, which are highly susceptive to NK cell-dependent immune-surveillance, to monitor the dissemination of lymphoma cells using an in vivo imaging system. The use of this model is expected to be a highly sensitive method to examine the role of NK cells in controlling lymphoma dissemination in a variety of tissues.

リンク情報
DOI
https://doi.org/10.1016/j.jim.2021.112993
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33609531
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85101243280&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85101243280&origin=inward
ID情報
  • DOI : 10.1016/j.jim.2021.112993
  • ISSN : 0022-1759
  • eISSN : 1872-7905
  • PubMed ID : 33609531
  • SCOPUS ID : 85101243280

エクスポート
BibTeX RIS