2015
Micrometer-sized network structure of novel DNA-lipid conjugates induced by heat stimulation
SOFT MATTER
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- Volume
- 11
- Number
- 35
- First page
- 7053
- Last page
- 7058
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1039/c5sm01456e
- Publisher
- ROYAL SOC CHEMISTRY
We have developed a novel lipid-bearing DNA that forms hairpin modules, including a single RNA monomer; this can be used to create micrometer-sized structures from nanometer-sized building blocks during breakage at the RNA site. In the presence of divalent metal ions and heat stimulation, we observed transition of the self-assembly, which results in the formation of a three-dimensional network structure. To our knowledge, this is also the first report of heat-induced micrometer-sized molecular self-assembly of molecules that carry biological information.
- Link information
- ID information
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- DOI : 10.1039/c5sm01456e
- ISSN : 1744-683X
- eISSN : 1744-6848
- Web of Science ID : WOS:000360460400017