2012年1月
Modification of the Glass Surface Property in PDMS-Glass Hybrid Microfluidic Devices
ANALYTICAL SCIENCES
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- 巻
- 28
- 号
- 1
- 開始ページ
- 39
- 終了ページ
- 44
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2116/analsci.28.39
- 出版者・発行元
- JAPAN SOC ANALYTICAL CHEMISTRY
This paper presents a simple method to change the hydrophilic nature of the glass surface in a poly(dimethylsiloxane) (PDMS)-glass hybrid microfluidic device to hydrophobic by an extra-heating step during the fabrication process. Glass substrates bonded to a native or oxygen plasma-treated PDMS chip having microchambers (12.5 mm diameter, 110 mu m height) were heated at 200 C for 3 h, and then the hydrophobicity of the glass surfaces on the substrate was evaluated by measuring the contact angle of water. By the extra-heating process, the glass surfaces became hydrophobic, and its contact angle was around 109, which is nearly the same as native PDMS surfaces. To demonstrate the usefulness of this surface modification method, a PDMS-glass hybrid microfluidic device equipped with microcapillary vent structures for pneumatic manipulation of droplets was fabricated. The feasibility of the microcapillary vent structures on the device with the hydrophobic glass surfaces are confirmed in practical use through leakage tests of the vent structures and liquid handling for the electrophoretic separation of DNA molecules.
- リンク情報
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- DOI
- https://doi.org/10.2116/analsci.28.39
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/22232222
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000299649800008&DestApp=WOS_CPL
- URL
- http://orcid.org/0000-0001-9873-2856
- ID情報
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- DOI : 10.2116/analsci.28.39
- ISSN : 0910-6340
- ORCIDのPut Code : 21841831
- PubMed ID : 22232222
- Web of Science ID : WOS:000299649800008