山田恭央 (Takahiro Yamada) - マイポータル

基本情報

所属: Yale University School of Medicine Department of Immunobiology Associate Research Scientist

ORCID iD: https://orcid.org/0000-0003-2613-5600
J-GLOBAL ID: 202301004788299552
researchmap会員ID: R000062120

腸内微生物と宿主の相互作用と、それを解き明かすための手法の開発に興味を持っています。

研究キーワード

研究分野

経歴

2026年4月 - 現在

Yale School of Medicine, Department of Immunobiology, Associate Research Scientist
2023年1月 - 2026年3月

Yale School of Medicine, Department of Immunobiology, Postdoctoral associate
2022年1月 - 2023年1月

Yale School of Medicine, Department of Immunobiology, Postdoctoral fellow
2020年4月 - 2021年12月

慶應義塾大学, 薬学部薬科学科, 特任助教

学歴

2015年4月 - 2020年3月

慶應義塾大学, 薬学研究科
2011年4月 - 2015年3月

慶應義塾大学, 薬学部, 薬科学科

受賞

論文

Human immunodeficiency virus-associated gut microbiome impacts systemic immunodeficiency and susceptibility to opportunistic gut infection.

Stavros Bashiardes, Melina Heinemann, Lorenz Adlung, Rafael Valdés-Mas, Jemal Ali Mahdi, Samuel P Nobs, Timur Tuganbaev, Takahiro Yamada, Max Horn, Uria Mor …

Nature microbiology 11(3) 690-703 2026年3月
A host-centric view of the microbiota metabolome.

Takahiro Yamada, Noah W Palm

Immunity 58(12) 2940-2956 2025年12月9日
AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine

Ryohtaroh Matsumoto, Kosuke Ogata, Daisuke Takahashi, Yusuke Kinashi, Takahiro Yamada, Ryo Morita, Keisuke Tanaka, Kouya Hattori, Mayumi Endo, Yumiko Fujimura …

Cellular and Molecular Life Sciences 81(1) 2024年10月5日査読有り
Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice

Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki …

eBioMedicine 106 105256-105256 2024年8月
Skate-skin mucin, rich in sulfated sugars and threonine, promotes proliferation of Akkermansia muciniphila in feeding tests in rats and in vitro fermentation using human feces

Takaaki Miyata, Takayasu Mizushima, Nobuyuki Miyamoto, Takahiro Yamada, Koji Hase, Michihiro Fukushima, Naomichi Nishimura, Shingo Hino, Tatsuya Morita

Bioscience, Biotechnology, and Biochemistry 2022年2月24日
Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice

Ryo Aoki, Masayoshi Onuki, Koya Hattori, Masato Ito, Takahiro Yamada, Kohei Kamikado, Yun-Gi Kim, Nobuhiro Nakamoto, Ikuo Kimura, Julie M. Clarke …

Microbiome 2021年12月
Safety and tolerability of medicinal parasite ova (Trichuris suis) in healthy Japanese volunteers: A randomized, double-blind, placebo-controlled trial

Tokio Hoshina, Tatsuya Sakurai, Hidetoshi Ichimura, Kenji Ishiwata, En Shitan, Takahiro Yamada, Lee Kwangyole, Akihiro Shimizu, Koji Hase, Hirotaka Kanuka

Parasitology International 102441-102441 2021年8月
Profiling of tumour-associated microbiota in human hepatocellular carcinoma.

Seiga Komiyama, Takahiro Yamada, Nobuyuki Takemura, Norihiro Kokudo, Koji Hase, Yuki I Kawamura

Scientific reports 2021年5月19日
Gut microbiota, determined by dietary nutrients, drive modification of the plasma lipid profile and insulin resistance.

Yoshiyuki Watanabe, Shiho Fujisaka, Kazutaka Ikeda, Masaki Ishikawa, Takahiro Yamada, Allah Nawaz, Tomonobu Kado, Takahide Kuwano, Ayumi Nishimura, Muhammad Bilal …

iScience 2021年4月16日
Polyamines polarized Th2/Th9 cell-fate decision by regulating GATA3 expression

Atsuo Nakamura, Daisuke Takahashi, Yutaka Nakamura, Takahiro Yamada, Mitsuharu Matsumoto, Koji Hase

Archives of Biochemistry and Biophysics 693 108587-108587 2020年10月
Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells

Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa …

EBioMedicine 2020年8月
Mucin-Derived O-Glycans Act as Endogenous Fiber and Sustain Mucosal Immune Homeostasis via Short-Chain Fatty Acid Production in Rat Cecum

Shingo Hino, Takayasu Mizushima, Katsunori Kaneko, Erika Kawai, Takashi Kondo, Tomomi Genda, Takahiro Yamada, Koji Hase, Naomichi Nishimura, Tatsuya Morita

The Journal of Nutrition 2020年4月
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Ikuo Kimura, Junki Miyamoto, Ryuji Ohue-Kitano, Keita Watanabe, Takahiro Yamada, Masayoshi Onuki, Ryo Aoki, Yosuke Isobe, Daiji Kashihara, Daisuke Inoue …

Science 367(6481) 2020年2月
Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity

Shunsuke Kimura, Yutaka Nakamura, Nobuhide Kobayashi, Katsuyuki Shiroguchi, Eiryo Kawakami, Mami Mutoh, Hiromi Takahashi-Iwanaga, Takahiro Yamada, Meri Hisamoto, Midori Nakamura …

Nature Communications 11(1) 2020年1月
Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis

Takahiro Yamada, Shingo Hino, Hideki Iijima, Tomomi Genda, Ryo Aoki, Ryuji Nagata, Kyu-Ho Han, Masato Hirota, Yusuke Kinashi, Hiroyuki Oguchi …

EBioMedicine 48 513-525 2019年10月
Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses

Motoyoshi Nagai, Ryotaro Noguchi, Daisuke Takahashi, Takayuki Morikawa, Kouhei Koshida, Seiga Komiyama, Narumi Ishihara, Takahiro Yamada, Yuki I. Kawamura, Kisara Muroi …

Cell 178(5) 1072-1087.e14 2019年8月
Therapeutic effect of vitamin D3-containing nanostructured lipid carriers on inflammatory bowel disease

Khadijah Zai, Masato Hirota, Takahiro Yamada, Narumi Ishihara, Takeshi Mori, Akihiro Kishimura, Koichiro Suzuki, Koji Hase, Yoshiki Katayama

Journal of Controlled Release 286 94-102 2018年9月
A partial agonist for retinoid X receptor mitigates experimental colitis

Masayoshi Onuki, Masaki Watanabe, Narumi Ishihara, Koichiro Suzuki, Kei Takizawa, Masato Hirota, Takahiro Yamada, Aiko Egawa, Osamu Shibahara, Midori Nishii …

International Immunology 31(4) 251-262 2018年
Intestinal Epithelial Cell-specific Deletion of α-Mannosidase II Ameliorates Experimental Colitis

Koichiro Suzuki, Takahiro Yamada, Keiko Yamazaki, Masato Hirota, Narumi Ishihara, Mizuki Sakamoto, Daisuke Takahashi, Hideki Iijima, Koji Hase

Cell Structure and Function 43(1) 25-39 2018年
The diet-microbiota-metabolite axis regulates the host physiology

Takahiro Yamada, Daisuke Takahashi, Koji Hase

Journal of Biochemistry 160(1) 1-10 2016年3月11日

MISC

炎症性腸疾患における腸内代謝物の異常とそのメカニズム

山田恭央長谷耕二

腸内細菌-宿主のクロストークとこれを修飾する食事要因 2019年5月
腸内エコロジーを支える生物間代謝経路

山田恭央, 長谷耕二

実験医学 36(18) 3064-3069 2018年11月筆頭著者

山田恭央

基本情報

研究キーワード

研究分野

経歴

学歴

受賞

論文

MISC

メニュー

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