脇田隆字 (Takaji Wakita) - 論文

Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies

Tetsuya Inoue, Yuichiro Yamamoto, Kaoru Sato, Yuko Okemoto-Nakamura, Yoshimi Shimizu, Motohiko Ogawa, Taishi Onodera, Yoshimasa Takahashi, Takaji Wakita, Mika K. Kaneko …

iScience 27(4) 109363-109363 2024年4月

Mpox Neutralizing Antibody Response to LC16m8 Vaccine in Healthy Adults.

Eriko Morino, Sohtaro Mine, Noriko Tomita, Yukari Uemura, Yosuke Shimizu, Sho Saito, Tetsuya Suzuki, Nobumasa Okumura, Haruka Iwasaki, Junko Terada …

NEJM evidence 3(3) EVIDoa2300290 2024年3月

Hepatocellular organellar abnormalities following elimination of hepatitis C virus.

Haruyo Aoyagi, Hiroko Iijima, Eman S Gaber, Takuma Zaitsu, Mami Matsuda, Kosho Wakae, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Jeffrey Kahn …

Liver international : official journal of the International Association for the Study of the Liver 43(8) 1677-1690 2023年8月

Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation.

Takayuki Abe, Yuki Marutani, Lin Deng, Chieko Matsui, Masayoshi Fukasawa, Ryosuke Suzuki, Takaji Wakita, Yoshiharu Matsuura, Ikuo Shoji

Journal of virology 97(6) e0065523 2023年6月5日

A Multicenter Randomized Controlled Trial To Evaluate the Efficacy and Safety of Nelfinavir in Patients with Mild COVID-19.

Taiga Miyazaki, Naoki Hosogaya, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Yoshihito Ozawa, Yuki Shiko, Yosuke Inaba …

Microbiology spectrum 11(3) e0431122 2023年5月4日

Oxaprozine analogue S169はin vitroでHBV感染を有意に抑制する(Oxaprozine analogue S169 significantly suppress HBV infection in vitro)

AlyIbrahim HusseinHassan, 加藤孝宣, 茶山一彰, 脇田隆字

肝臓 64(Suppl.1) A470-A470 2023年4月

N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx.

Takayuki Murata, Satoko Iwahori, Yusuke Okuno, Hironori Nishitsuji, Yusuke Yanagi, Koichi Watashi, Takaji Wakita, Hiroshi Kimura, Kunitada Shimotohno

International journal of molecular sciences 24(3) 2023年1月23日

Identification of neutralizing epitopes in the preS2 domain of the hepatitis B virus.

Keigo Yato, Mami Matsuda, Kento Fukano, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, Kunitada Shimotohno, Koji Tamura, Takaji Wakita, Masamichi Muramatsu …

Virus research 323 199014-199014 2023年1月2日

National seroepidemiological study of COVID‐19 after the initial rollout of vaccines: Before and at the peak of the Omicron‐dominant period in Japan

Takeshi Arashiro, Satoru Arai, Ryo Kinoshita, Kanako Otani, Sho Miyamoto, Daisuke Yoneoka, Taro Kamigaki, Hiromizu Takahashi, Hiromi Hibino, Mai Okuyama …

Influenza and Other Respiratory Viruses 17(2) 2023年1月査読有り

Direct Inhibition of SARS-CoV-2 Spike Protein by Peracetic Acid.

Yuichiro Yamamoto, Yoshio Nakano, Mana Murae, Yoshimi Shimizu, Shota Sakai, Motohiko Ogawa, Tomoharu Mizukami, Tetsuya Inoue, Taishi Onodera, Yoshimasa Takahashi …

International journal of molecular sciences 24(1) 2022年12月20日

Independent evolution of multi-dominant viral genome species observed in a hepatitis C virus carrier.

Tomomi Ando, Hideki Aizaki, Masaya Sugiyama, Tomoko Date, Kazuhiko Hayashi, Masatoshi Ishigami, Yoshiaki Katano, Hidemi Goto, Masashi Mizokami, Masamichi Muramatsu …

Biochemistry and biophysics reports 32 101327-101327 2022年12月

SEB genotyping: SmartAmp-Eprimer binary code genotyping for complex, highly variable targets applied to HBV

Diane Delobel, Yutaka Furutani, Sumiko Nagoshi, Akihito Tsubota, Akio Miyasaka, Koichi Watashi, Takaji Wakita, Tomokazu Matsuura, Kengo Usui

BMC Infectious Diseases 22(1) 2022年12月

A single mutation in the E2 glycoprotein of hepatitis C virus broadens the claudin specificity for its infection.

Yoshitaka Shirasago, Hidesuke Fukazawa, Shotaro Nagase, Yoshimi Shimizu, Tomoharu Mizukami, Takaji Wakita, Tetsuro Suzuki, Hideki Tani, Masuo Kondoh, Takuya Kuroda …

Scientific reports 12(1) 20243-20243 2022年11月24日

エンテカビル耐性B型肝炎ウイルスポリメラーゼの生化学的および構造学的性質

中嶋章悟, 渡士幸一, 加藤孝宣, 村松正道, 脇田隆字, 安武義晃, 豊田哲也

日本生化学会大会プログラム・講演要旨集 95回 2T08a-09 2022年11月

エンテカビル耐性B型肝炎ウイルスポリメラーゼの生化学的および構造学的性質

中嶋章悟, 渡士幸一, 加藤孝宣, 村松正道, 脇田隆字, 安武義晃, 豊田哲也

日本生化学会大会プログラム・講演要旨集 95回 2T08a-09 2022年11月

Development and Use of a Kinetical and Real-Time Monitoring System to Analyze the Replication of Hepatitis C Virus

Xiaoyu Li, Masahiko Ito, Haruyo Aoyagi, Asako Murayama, Hideki Aizaki, Masayoshi Fukasawa, Takanobu Kato, Takaji Wakita, Tetsuro Suzuki

International Journal of Molecular Sciences 23(15) 8711-8711 2022年8月5日

Genome-wide CRISPR screen for HSV-1 host factors reveals PAPSS1 contributes to heparan sulfate synthesis.

Takeshi Suzuki, Yoshitaka Sato, Yusuke Okuno, Fumi Goshima, Tadahisa Mikami, Miki Umeda, Takayuki Murata, Takahiro Watanabe, Koichi Watashi, Takaji Wakita …

Communications biology 5(1) 694-694 2022年7月19日

Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action

Masaaki Toyama, Koichi Watashi, Masanori Ikeda, Atsuya Yamashita, Mika Okamoto, Kohji Moriishi, Masamichi Muramatsu, Takaji Wakita, Ashoke Sharon, Masanori Baba

Antimicrobial Agents and Chemotherapy 2022年5月23日

Structural insights into the HBV receptor and bile acid transporter NTCP.

Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani …

Nature 606(7916) 1027-1031 2022年5月17日

Hepatitis C Virus-Induced ROS/JNK Signaling Pathway Activates the E3 Ubiquitin Ligase Itch to Promote the Release of HCV Particles via Polyubiquitylation of VPS4A.

Lin Deng, Yujiao Liang, Adi Ariffianto, Chieko Matsui, Takayuki Abe, Masamichi Muramatsu, Takaji Wakita, Masatoshi Maki, Hideki Shibata, Ikuo Shoji

Journal of virology 96(6) e0181121 2022年3月23日

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